A pH-sensitive histidine residue as control element for ligand release from HLA-DR molecules

Proceedings of the National Academy of Sciences of the United States of America

Volumn 99, Issue 26, 2002, Pages 16946-16950

  Rötzschke, Olaf ^a,b   Lau, Julie M ^a   Hofstätter, Maria ^b   Falk, Kirsten ^a,b   Strominger, Jack L ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

HISTIDINE; HLA DR ANTIGEN; IMIDAZOLE; LIGAND; PEPTIDE; TYROSINE; VALINE;

AMINO ACID ANALYSIS; AMINO ACID SUBSTITUTION; ARTICLE; CONFORMATION; CORRELATION ANALYSIS; HALF LIFE TIME; HYDROPHOBICITY; PH; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; REGULATORY MECHANISM; SOLUBILITY; TITRIMETRY;

AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, DIFFERENTIATION, B-LYMPHOCYTE; HISTIDINE; HISTOCOMPATIBILITY ANTIGENS CLASS II; HLA-D ANTIGENS; HLA-DP ANTIGENS; HLA-DQ ANTIGENS; HLA-DR ANTIGENS; HUMANS; HYDROGEN-ION CONCENTRATION; LIGANDS; MICE; MOLECULAR SEQUENCE DATA;

EID: 0037168548     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.212643999     Document Type: Article

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