Evaluation of the acute and subacute toxicity of a choleretic phloracetophenone in experimental animals

Toxicology Letters

Volumn 129, Issue 1-2, 2002, Pages 123-132

  Piyachaturawat, Pawinee ^a   Tubtim, Chatsuda ^a   Chuncharunee, Aporn ^b   Komaratat, Prayad ^a   Suksamrarn, Apichart ^c  

^a Mahidol University   (Thailand)

^b MAHIDOL UNIVERSITY   (Thailand)

^c RAMKHAMHAENG UNIVERSITY   (Thailand)

Author keywords

Acute toxicity; Cholestasis; Phloracetophenone; Subacute toxicity

Indexed keywords

2,4,6 TRIHYDROXYACETOPHENONE; ALANINE; ALKALINE PHOSPHATASE; AMINOTRANSFERASE; ASPARTIC ACID; BILIRUBIN; BROMSULFOPHTHALEIN; CHOLERETIC AGENT; ETHINYLESTRADIOL; NITROGEN; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; UREA;

ACUTE TOXICITY; AGE; ALKALINE PHOSPHATASE BLOOD LEVEL; AMINO ACID BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BILIRUBIN BLOOD LEVEL; BODY WEIGHT; CELL DEGENERATION; CHOLESTASIS; CONTROLLED STUDY; DOSE RESPONSE; DRUG ACTIVITY; DRUG EFFECT; DRUG MEGADOSE; DRUG SCREENING; ENZYME BLOOD LEVEL; EXPERIMENTAL ANIMAL; FEMALE; HAMSTER; LD 50; LIVER CELL; LIVER CLEARANCE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT; SEX; SPECIES DIFFERENCE; TOXICITY; TRIACYLGLYCEROL BLOOD LEVEL; UREA NITROGEN BLOOD LEVEL;

ACETOPHENONES; ADENOSINE TRIPHOSPHATASES; ANIMALS; BILE; CHOLAGOGUES AND CHOLERETICS; CRICETINAE; DOSE-RESPONSE RELATIONSHIP, DRUG; ETHINYL ESTRADIOL; FEMALE; LETHAL DOSE 50; LIVER; MALE; MESOCRICETUS; MICE; RATS; RATS, WISTAR;

ANIMALIA; CRICETINAE;

EID: 0037165492     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4274(02)00006-1     Document Type: Article

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