Translocation of lipid-linked oligosaccharides across the ER membrane requires Rft1 protein

Nature

Volumn 415, Issue 6870, 2002, Pages 447-450

  Helenius, Jonne ^a   Ng, Davis T W ^b   Marolda, Cristina L ^c   Walter, Peter ^d   Valvano, Miguel A ^c   Aebi, Markus ^a  

^a ETH ZURICH   (Switzerland)

^b PENNSYLVANIA STATE UNIVERSITY   (United States)

^c UNIVERSITY OF WESTERN ONTARIO   (Canada)

^d HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MEMBRANES; BIOSYNTHESIS; CELLS; POLYPEPTIDES; PROTEINS;

CONSERVED PATHWAY;

LIPIDS;

ASPARAGINE; FLIPPASE; GLYCOLIPID; LIPID; MEMBRANE PROTEIN; OLIGOSACCHARIDE; PROTEIN RFT1; UNCLASSIFIED DRUG;

BIOCHEMISTRY; EUKARYOTE; PROTEIN; TRANSLOCATION;

ARTICLE; BIOSYNTHESIS; CARBOHYDRATE SYNTHESIS; CARBOHYDRATE TRANSPORT; CATALYSIS; CHEMICAL REACTION; CONTROLLED STUDY; CYTOPLASM; ENDOPLASMIC RETICULUM; EUKARYOTIC CELL; NONHUMAN; PREDICTION; PRIORITY JOURNAL; PROTEIN GLYCOSYLATION; REACTION ANALYSIS; YEAST;

ASPARAGINE; BIOLOGICAL TRANSPORT; CARRIER PROTEINS; CONSERVED SEQUENCE; ENDOPLASMIC RETICULUM; GLYCOSYLATION; INTRACELLULAR MEMBRANES; LIPID METABOLISM; MEMBRANE GLYCOPROTEINS; MEMBRANE PROTEINS; OLIGOSACCHARIDES; PHOSPHOLIPID TRANSFER PROTEINS; POLYISOPRENYL PHOSPHATE OLIGOSACCHARIDES; RECOMBINANT FUSION PROTEINS; SACCHAROMYCES CEREVISIAE PROTEINS;

EUKARYOTA;

EID: 0037165138     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/415447a     Document Type: Article

References (28)

1. Assembly of asparagine-linked oligosaccharides
2. From peptidoglycan to glycoproteins: Common features of lipid-linked oligosaccharide biosynthesis
3. Flip-flop: The transmembrane translocation of lipids
4. How proteins move lipids and lipids move proteins
5. Transport of fatty acids and metabolites across the peroxisomal membrane
6. ABC transporters in lipid transport
7. Topography of glycosylation reactions in the endoplasmic reticulum
8. The dolichol pathway of N-glycosylation
9. Topography of glycosylation reactions in the rough endoplasmic reticulum membrane
10. Transmembrane movement of oligosaccharide-lipids during glycoprotein synthesis
11. Paramagnetic isoprenoid carrier lipids. 1. Chemical synthesis and incorporation into model membranes
12. The topological orientation of N, N′-diacetylchitobiosylpyrophosphoryldolichol in artificial and natural membranes
13. Yeast mutants deficient in protein glycosylation
14. The Yeast ALG11 gene specifies addition of the terminal alpha 1,2-Man to the Man5GlcNAc2-PP-dolichol N-glycosylation intermediate formed on the cytosolic side of the endoplasmic reticulum
15. The unfolded protein response regulates multiple aspects of secretory and membrane protein biogenesis and endoplasmic reticulum quality control
16. Glycobiology of Plasmodium falciparum
17. Carbohydrate moiety of carboxypeptidase Y and perturbation of its biosynthesis
18. Cloning and characterization of the ALG3 gene of Saccharomyces cerevisiae
19. Dolichol phosphate mannose synthase is required in vivo for glycosyl phosphatidylinositol membrane anchoring, O-mannosylation, and N-glycosylation of protein in Saccharomyces cerevisiae
20. Analysis of glycoproteins from Saccharomyces cerevisiae
21. 9GlcNAc
22. Transmembrane movement of a water-soluble analogue of mannosylphosphoryldolichol is mediated by an endoplasmic reticulum protein
23. Molecular cloning of human plasma membrane phospholipid scramblase. A protein mediating transbilayer movement of plasma membrane phospholipids
24. Expression cloning and characterization of a novel adipocyte long chain fatty acid transport protein
25. The activity of a putative polyisoprenol-linked sugar translocase (Wzx) involved in Escherichia coli O antigen assembly is independent of the chemical structure of the O repeat
26. Guide to yeast genetics and molecular biology
27. STT 3, a highly conserved protein required for yeast oligosaccharyltransferase activity in vitro