Time-programmed pulsatile release of dextran from calcium-alginate gel beads coated with carboxy-n-propylacrylamide copolymers

Journal of Controlled Release

Volumn 80, Issue 1-3, 2002, Pages 57-68

  Iskakov, Rinat M ^a   Kikuchi, Akihiko ^a   Okano, Teruo ^a  

^a TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

Author keywords

Calcium alginate gel beads; Copolymer coating; Macromolecular drugs; Poly(carboxy n propylacrylamide co dimethylacrylamide); Pulsatile drug release system; Time programmed release

Indexed keywords

ACRYLAMIDE DERIVATIVE; ALGINIC ACID; CALCIUM ALGINATE; CALCIUM ION; COPOLYMER; DRUG CARRIER; FLUORESCEIN ISOTHIOCYANATE DEXTRAN; SODIUM ION;

ARTICLE; CONTROLLED RELEASE FORMULATION; DELAYED RELEASE FORMULATION; DISSOCIATION; DRUG DIFFUSION; DRUG RELEASE; GEL; MOLECULAR WEIGHT; OSMOTIC PRESSURE; PRIORITY JOURNAL; PULSATILE DRUG RELEASE; REGULATORY MECHANISM;

ACRYLIC RESINS; ALGINATES; ANTICOAGULANTS; BIOCOMPATIBLE MATERIALS; DELAYED-ACTION PREPARATIONS; DEXTRANS; GELS; GLUCURONIC ACID; HEXURONIC ACIDS; POLYMERS;

EID: 0037161340     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(01)00551-X     Document Type: Article

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