Sp/Krüppel-like transcription factors are essential for the expression of mitochondrial glycerol phosphate dehydrogenase promoter B

Gene

Volumn 296, Issue 1-2, 2002, Pages 221-234

  Hasan, Noaman M ^a   MacDonald, Michael J ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

Eukaryotic promoter; Gene expression; Insulinoma INS 1 cell; Transcription factor

Indexed keywords

BASIC KRUPPEL LIKE FACTOR; BINDING PROTEIN; DNA; ERYTHROID KRUPPEL LIKE FACTOR; GLUCOSE; GLYCEROL 3 PHOSPHATE DEHYDROGENASE; OLIGONUCLEOTIDE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR PU 1; TRANSCRIPTION FACTOR SP1; TRANSCRIPTION FACTOR SP3; UNCLASSIFIED DRUG; DNA BINDING PROTEIN; ERYTHROID KRUPPEL-LIKE FACTOR; GA BINDING PROTEIN; HYBRID PROTEIN; KLF3 PROTEIN, HUMAN; KRUPPEL LIKE FACTOR; LUCIFERASE; ONCOPROTEIN; PROTO ONCOGENE PROTEIN SPI 1; PROTO-ONCOGENE PROTEIN SPI-1; REPRESSOR PROTEIN; SP3 PROTEIN, HUMAN; SP3 PROTEIN, RAT; SP4 PROTEIN, HUMAN; TRANSACTIVATOR PROTEIN; TRANSCRIPTION FACTOR SP4;

ANIMAL CELL; ARTICLE; BINDING SITE; CELL; CELL LINE; CONTROLLED STUDY; DNA BINDING; DROSOPHILA; GENE ACTIVATION; GENE CONTROL; GENE DELETION; GENE EXPRESSION REGULATION; GENE SEQUENCE; GENETIC ANALYSIS; GENETIC TRANSFECTION; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; ANIMAL; CELL CULTURE; ENZYMOLOGY; GEL MOBILITY SHIFT ASSAY; GENETICS; HELA CELL; HUMAN; METABOLISM; MITOCHONDRION; MOLECULAR GENETICS; MUTAGENESIS; MUTATION; NUCLEOTIDE SEQUENCE; PROTEIN BINDING; RAT;

EUKARYOTA;

ANIMALS; BASE SEQUENCE; BINDING SITES; CELL LINE; DNA; DNA-BINDING PROTEINS; ELECTROPHORETIC MOBILITY SHIFT ASSAY; GA-BINDING PROTEIN TRANSCRIPTION FACTOR; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLYCEROLPHOSPHATE DEHYDROGENASE; HELA CELLS; HUMANS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; LUCIFERASES; MITOCHONDRIA; MOLECULAR SEQUENCE DATA; MUTAGENESIS; MUTAGENESIS, INSERTIONAL; MUTATION; OLIGONUCLEOTIDES; PROMOTER REGIONS (GENETICS); PROTEIN BINDING; PROTO-ONCOGENE PROTEINS; RATS; RECOMBINANT FUSION PROTEINS; REPRESSOR PROTEINS; SEQUENCE DELETION; SP1 TRANSCRIPTION FACTOR; SP3 TRANSCRIPTION FACTOR; SP4 TRANSCRIPTION FACTOR; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0037151776     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1119(02)00865-X     Document Type: Article

References (27)

1. Chen Y., Su M., Walia R.R., Hao Q., Covington J.W., Vaughan D.E. Sp1 sites mediate activation of the plasminogen activator inhibitor-1 promoter by glucose in vascular smooth muscle cells. J. Biol. Chem. 273:1998;8225-8231.
2. Courey A.J., Tjian R. Analysis of Sp1 in vivo reveals multiple transcriptional domains, including a novel glutamine-rich activation motif. Cell. 55:1988;887-898.
3. Courey A.J., Holtzaman D.A., Jackson S.P., Tjian R. Synergistic activation by the glutamine-rich domains of human transcription factor Sp1. Cell. 59:1989;827-836.
4. Crossley M., Whitelaw E., Perkins A., Williams G., Fujiwara Y., Orkin S.H. Isolation and characterization of the cDNA encoding BKLF/TEF-2, a major CACCC-box-binding protein in erythroid cells and selected other cells. Mol Cell Biol. 16:1996;1695-1705.
5. Daniel S., Zhang S., DePaoli-Roach A.A., Kim K. Dephosphorylation of Sp1 by protein phosphatase 1 is involved in the glucose-mediated activation of the acetyl-CoA carboxylase gene. J. Biol. Chem. 271:1996;14692-14697.
6. Dynan W.S., Tjian R. The promoter-specific transcription factor Sp1 binds to upstream sequences in the SV40 early promoter. Cell. 35:1983;79-87.
7. Feng W.C., Southwood C.M., Bieker J.J. Analyses of beta-thalassemia mutant DNA interactions with erythroid Kruppel-like factor (EKLF), an erythroid cell-specific transcription factor. J Biol. Chem. 269:1994;1493-1500.
8. Fernandez-Alvarez J., Conget I., Rasschaert J., Sener A., Gomis R., Malaisse W.J. Enzymatic, metabolic and secretory patterns in human islets of type 2 (non-insulin-dependent) diabetic patients. Diabetologia. 37:1994;177-181.
9. Fukuda H., Iritani N. Regulation of ATP citrate-lyase gene expression in hepatocytes and adipocytes in normal and genetically obese rats. J. Biochem. Tokyo. 126:1999;437-444.
10. Gill G., Pascal E., Tseng Z.H., Tjian R. A glutamine-rich hydrophobic patch in transcription factor Sp1 contacts the dTAF11110 component of the Drosophila TFIID complex and mediates transcriptional activation. Proc. Natl. Acad. Sci. USA. 91:1994;192-196.
11. Gong Q., Brown L.J., MacDonald M.J. Functional analysis of two promoters for the human mitochondrial glycerol phosphate dehydrogenase gene. J. Biol. Chem. 275:2000;38012-38021.
12. Hagen G., Muller S., Beato M., Suske G. Sp1-mediated transcriptional activation is repressed by Sp3. EMBO J. 13:1994;3843-3851.
13. Hata Y., Duh E., Zhang K., Robinson G.S., Aiello L.P. Transcription factors Sp1 and Sp3 alter vascular endothelial growth factor receptor expression through a novel recognition sequence. J. Biol. Chem. 273:1998;19294-19303.
14. Ihn H., LeRoy E.C., Trojanowska M. Oncostatin M stimulates transcription of the human alpha2(I) collagen gene via the Sp1/Sp3-binding site. J. Biol. Chem. 272:1997;24666-24672.
15. R′ promoter and its mutants. Gene. 81:1989;1-15.
16. MacDonald M.J. High content of mitochondrial glycerol-3-phosphate dehydrogenase in pancreatic islets and its inhibition by diazoxide. J. Biol. Chem. 256:1981;8287-8290.
17. MacDonald M.J. Elusive proximal signals of beta-cells for insulin secretion. Diabetes. 39:1990;1461-1466.
18. MacDonald M.J., Efendic S., Ostenson C.-G. Normalization by insulin treatment of low mitochondrial glycerol phosphate dehydrogenase and pyruvate carboxylase in pancreatic islets of the GK rat. Diabetes. 45:1996;886-890.
19. Merika M., Orkin S.H. Functional synergy and physical interactions of the erythroid transcription factor GATA-1 with the Krüppel family proteins Sp1 and EKLF. Mol. Cell. Biol. 15:1995;2437-2447.
20. Miller I.J., Bieker J.J. A novel, erythroid cell-specific murine transcription factor that binds to the CACCC element and is related to the Kruppel family of nuclear proteins. Mol. Cell. Biol. 13:1993;2776-2786.
21. Rosmarin A.G., Luo M., Caprio D.G., Shang J., Simkevich C.P. Sp1 cooperates with the ets transcription factor, GABP, to activate the CD18 (2 leukocyte integrin) promoter. J. Biol. Chem. 273:1998;13097-13103.
22. Sawada J., Simizu N., Suzuki F., Sawa C., Goto M., Hasegawa M., Imai T., Watanabe H., Handa H. Synergistic transcriptional activation by hGABP and select members of the activation transcription factor/cAMP response element-binding protein family. J. Biol. Chem. 274:1999;35475-35482.
23. Suske G. The Sp-family of transcription factors. Gene. 238:1999;291-300.
24. Turner J., Crossley M. Cloning and characterization of mCtBP2, a co-repressor that associates with basic Krüppel-like factor and other mammalian transcriptional regulators. EMBO J. 17:1998;5129-5140.
25. Turner J., Crossley M. Basic Kruppel-like factor functions within a network of interacting haematopoietic transcription factors. Int. J. Biochem. Cell. Biol. 31:1999;1169-1174.
26. Weitzel J.M., Grott S., Radtke C., Kutz S., Seitz H.J. Multiple promoters direct the tissue-specific expression of rat mitochondrial glycerol-3-phosphate dehydrogenase. Biol. Chem. 381:2000;611-614.
27. Zhang P., Klenk E.S., Lazzaro M.A., Williams L.B., Considine R.V. Hexosamines regulate leptin production in 3T3-L1 adipocytes through transcriptional mechanisms. Endocrinology. 143:2002;99-106.