Priming effects of novel nonsteroidal progesterone receptor modulators CP8816 and CP8863 on the development of adenomyosis in the mouse uterus

Life Sciences

Volumn 71, Issue 5, 2002, Pages 527-535

  Mori, Takao ^a   Kurata, Yasushi ^b   Tabata, Yuji ^b   Niho, Naoko ^b,c   Matsuda, Manabu ^a   Zhou, Ying Fang ^a,d  

^a UNIVERSITY OF TOKYO   (Japan)

^b MEIJI SEIKA KAISHA LTD   (Japan)

^c NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

^d PEKING UNIVERSITY   (China)

Author keywords

Adenomyosis; Mice; Modulator; Nonsteroid; Progesterone

Indexed keywords

6 (N,N DIMETHYLAMINOCARBONYL)OXY 7 METHOXY 4A,5,6,7 TETRAHYDRO 1,3,4A,5 TETRAMETHYLBENZ[F]INDOL 2(4H) ONE; 7 HYDROXY 6 (N METHYLCARBAMOYL)OXY 4A,5,6,7 TETRAHYDRO 1,3,4A,5 TETRAMETHYLBENZ[F]INDOL 2(4H) ONE; COLCHICINE; CP 8816; CP 8863; ESTRADIOL; PROGESTERONE; PROGESTERONE RECEPTOR MODULATOR; UNCLASSIFIED DRUG;

ADENOHYPOPHYSIS; ADENOMYOSIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DIVISION; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; EPITHELIUM CELL; FEMALE; ISOGRAFT; MITOSIS RATE; MOUSE; NONHUMAN; STROMA CELL;

ANIMALS; ENDOMETRIOSIS; ESTRADIOL; FEMALE; FURANS; HUMANS; INDOLES; LIGANDS; MALE; MICE; NAPHTHOLS; OVARIECTOMY; PITUITARY GLAND, ANTERIOR; PROGESTERONE; RECEPTORS, PROGESTERONE; SESQUITERPENES; UTERUS;

EID: 0037150770     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0024-3205(02)01727-7     Document Type: Article

References (29)

1. Progestin regulation of cellular proliferation
2. Reproductive phenotypes of the progesterone receptor null mutant mouse
3. Progesterone and estradiol interaction in the regulation of rat uterine weight and estrogen receptor concentration
4. Oestrogen-gestagen interactions on mitosis in target tissues
5. Cellular aspects of ovum implantation and decidualization in the rat
6. The effect of progesterone and progestins on endometrial proliferation
7. Mifepristone (RU486): A review
8. Endometrial cancer and combined oral contraceptives: The WHO Collaborative Study of Neoplasia and Steroid Contraceptives
9. Progesterone receptor modulator and progesterone antagonists in women's health
10. Progestins: Present and future
11. Adenomyosis: Current perspectives
12. The induction of adenomyosis in mice by intrauterine pituitary isografts
13. Effects of prenatal exposure of mice to "low-dose" diethylstilbestrol and the development of adenomyosis associated with evidence of hyperprolactinemia
14. Mechanisms of development of prolactin-induced adenomyosis in mice
15. Ectopic pituitary grafts in mice: Hormone levels, effects on fertility, and the development of adenomyosis uteri, prolactinomas, and mammary carcinomas
16. Prolactin and uterine adenomyosis in mice
17. Multiple endocrine syndrome in SHN mice: Mammary tumors and uterine adenomyosis
18. Increase of DNA synthesis in uterine adenomyosis in mice with ectopic pituitary isograft
19. Novel conservative medical therapy for uterine adenomyosis with a danazol-loaded intrauterine device
20. Suppression of development of uterine adenomyosis by danazol treatment in mice
21. PF1092A, B and C, new nonsteroidal progesterone receptor ligands produced by Penicillium oblatum. I. Taxonomy of producing strain, fermentation, isolation and biological activities
22. PF1092A, B and C, new nonsteroidal progesterone receptor ligands produced by Penicillium oblatum. II. Physico-chemical properties and structure elucidation
23. Hormone-dependent changes in A and B forms of progesterone receptor
24. Determinants for the repression of estrogen receptor transcriptional activity by ligand-occupied progestin receptors
25. Transit of normal rat uterine stromal cells through G1 phase of the cell cycle requires progesterone-growth factor interactions
26. Mechanisms of action and cross-talk between estrogen receptor and progesterone receptor pathways
27. The partial agonist activity of antagonist-occupied steroid receptors is controlled by a novel hinge domain-binding coactivator L7/SPA and the corepressors N-CoR or SMRT
28. Prevention of endometrial hyperplasia by progesterone during long-term estradiol replacement: Influence of bleeding pattern and secretory changes
29. Endometrial glandular proliferation and estrogen receptor content during the normal menstrual cycle