Isolation and characterization of modified species of a mutated (Cys125-Ala) recombinant human interleukin-2

Journal of Chromatography A

Volumn 971, Issue 1-2, 2002, Pages 129-142

  Moya, Galina ^a   González, Luis Javier ^a   Huerta, Vivian ^a   García, Yairet ^a   Morera, Vivian ^a   Pérez, Danny ^a   Breña, Fidel ^a   Araña, Manuel ^a  

^a CENTER FOR GENETIC ENGINEERING AND BIOTECHNOLOGY   (Cuba)

Author keywords

Interleukins; Peptides

Indexed keywords

AMINO ACIDS; CHEMICAL BONDS; GENETIC ENGINEERING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ION EXCHANGE; MUTAGENESIS;

EDMAN DEGRADATION;

PROTEINS;

ACETONITRILE; ALANINE; CYSTEINE; RECOMBINANT INTERLEUKIN 2; THREONINE;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; COVALENT BOND; DRUG ISOLATION; DRUG PURIFICATION; HYDROPHOBICITY; ION EXCHANGE CHROMATOGRAPHY; MASS SPECTROMETRY; OXIDATION; PEPTIDE MAPPING; PRIORITY JOURNAL; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

ALANINE; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, ION EXCHANGE; CYSTEINE; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HUMANS; INTERLEUKIN-2; MOLECULAR SEQUENCE DATA; RECOMBINANT PROTEINS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 0037144220     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0021-9673(02)00845-2     Document Type: Article

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