The effects of unilateral removal of the cerebellar hemispheres on motor functions and weight gain in rats

Brain Research

Volumn 950, Issue 1-2, 2002, Pages 231-238

  Colombel, C ^a   Lalonde, R ^a   Caston, J ^a  

^a UNIVERSITÉ DE ROUEN   (France)

Author keywords

Cerebellum; Motor learning: lateralization; Motor skill

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANOREXIA; ARTICLE; BODY GROWTH; BRAIN REGION; CEREBELLECTOMY; CEREBELLUM INJURY; CONTROLLED STUDY; DYSPRAXIA; GROWTH RATE; HEMISPHERIC DOMINANCE; MALE; MORTALITY; MOTOR COORDINATION; MOTOR PERFORMANCE; NONHUMAN; PRIORITY JOURNAL; RAT; TASK PERFORMANCE; WEIGHT GAIN;

ANIMALS; CEREBELLUM; FUNCTIONAL LATERALITY; MALE; MOTOR ACTIVITY; MOTOR CORTEX; MOTOR SKILLS; RATS; SURVIVAL RATE; WEIGHT GAIN;

EID: 0037144213     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(02)03043-3     Document Type: Article

References (36)

1. Aiba A., Kano M., Chen C., Stanton M.E., Fox G.D., Herrup K., Zwingman T.A., Tonegawa S. Deficient cerebellar long-term depression and impaired motor learning in mGluR1 mutant mice. Cell. 79:1994;377-388.
2. Auvray N., Caston J., Reber A., Stelz T. Role of the cerebellum in the ontogenesis of equilibrium behavior in the young rat: a behavioral study. Brain Res. 505:1989;291-301.
3. Caston J., Delhaye-Bouchaud N., Mariani J. Motor behavior of heterozygous staggerer mutant (+/sg) versus normal (+/+) mice during aging. Behav. Brain Res. 72:1996;97-102.
4. Caston J., Devulder B., Jouen F., Lalonde R., Delhaye-Bouchaud N., Mariani J. Role of an enriched environment on the restoration of behavioral deficits in Lurcher mutant mice. Dev. Psychobiol. 35:1999;291-303.
5. Caston J., Jones N., Stelz T. Role of preoperative and postoperative sensorimotor training on restoration of the equilibrium behavior in adult mice following cerebellectomy. Neurobiol. Learn. Mem. 64:1995;195-202.
6. Caston J., Lalonde R., Delhaye-Bouchaud N., Mariani J. The cerebellum and postural sensorimotor learning in mice and rats. Behav. Brain Res. 95:1998;17-22.
7. Caston J., Vasseur F., Stelz T., Chianale C., Delhaye-Bouchaud N., Mariani J. Differential roles of cerebellar cortex and deep cerebellar nuclei in the learning of the equilibrium behavior: studies in intact and cerebellectomized lurcher mutant mice. Dev. Brain Res. 86:1995;311-316.
8. Chen C., Kano M., Abeliovich A., Chen L., Bao S., Kim J.J., Hashimoto K., Thompson R.F., Tonegawa S. Impaired motor co-ordination correlates with persistent multiple climbing fiber innervation in PKCγ mutant mice. Cell. 83:1995;1233-1242.
9. Dada M.O., Campbell G.T., Horacek M.J., Blake C.A. Intraperitoneal injection of chloral hydrate causes intra-abdominal adhesions and unilateral testicular atrophy in golden Syrian hamsters. Life Sci. 51:1992;29-35.
10. Dahhaoui M., Caston J., Auvray N., Reber A. Role of the cerebellum in an avoidance conditioning task in the rat. Physiol. Behav. 47:1990;1175-1180.
11. Dailey A.T., McKhann G.M., Berger M.S. The pathophysiology of oral pharyngeal apraxia and mutism following posterior fossa tumor resection in children. J. Neurosurg. 83:1995;467-475.
12. Di Lazzaro V., Restuccia D., Nardone R., Leggio M.G., Oliviero A., Profice P., Tonali P., Molinari M. Motor cortex changes in a patient with hemicerebellectomy. Electroencephalogr. Clin. Neurophysiol. 97:1995;259-263.
13. Gerlai R., Millen K.J., Herrup K., Fabien K., Joyner A.L., Roder J. Impaired motor learning performance in cerebellar En-2 mutant mice. Behav. Neurosci. 110:1996;126-133.
14. Guastavino J.M., Sotelo C., Damez-Kinselle I. Hot-foot murine mutation: behavioral effects and neuroanatomical alterations. Brain Res. 523:1990;199-210.
15. Guillaumin S., Dahhaoui M., Caston J. Cerebellum and memory: an experimental study in the rat using a passive avoidance conditioning task. Physiol. Behav. 49:1991;507-511.
16. Haines D.E., Dietrichs E. A HRP study of hypothalamo-cerebellar and cerebello-hypothalamic connections in squirrel monkey (Saimiri sciureus). J. Comp. Neurol. 229:1984;559-575.
17. Haines D.E., May P.J., Dietrichs E. Neuronal connections between the cerebellar nuclei and hypothalamus in Macaca fascicularis: cerebello-visceral circuits. J. Comp. Neurol. 299:1990;106-122.
18. Hilber P., Caston J. Motor skills and motor learning in Lurcher mutant mice during ageing. Neuroscience. 102:2001;615-623.
19. Jones N., Stelz T., Batini C., Caston J. Effects of lesion of the inferior olivary complex in learning of the equilibrium behavior in the young rat during ontogenesis. I. Total lesion of the inferior olive by 3-acetylpyridine. Brain Res. 697:1995;216-224.
20. Joyal C.C., Meyer C., Jacquart G., Mahler P., Caston J., Lalonde R. Effects of midline and lateral cerebellar lesions on motor coordination and spatial orientation. Brain Res. 739:1996;1-11.
21. Lalonde R., Strazielle C. Motor performance of spontaneous murine mutations with cerebellar atrophy. Crusio W.E., Gerlai R.T., Handbook of Molecular-Genetic Techniques for Brain and Behavior Research. 1999;627-637 Elsevier, Amsterdam.
22. Lalonde R., Filali M., Bensoula A.N., Lestienne F. Sensorimotor learning in three cerebellar mutant mice. Neurobiol. Learn. Mem. 65:1996;113-120.
23. Le Marec N., Caston J., Lalonde R. Impaired motor skills on static and mobile beams in Lurcher mutant mice. Exp. Brain Res. 116:1997;131-138.
24. Le Marec N., Stelz T., Delhaye-Bouchaud N., Mariani J., Caston J. Effect of cerebellar granule cell depletion on learning of the equilibrium behaviour: study in postnatally X-irradiated rats. Eur. J. Neurosci. 9:1997;2472-2478.
25. Mahler P., Guastavino J.M., Jacquart G., Strazielle C. An unexpected role of the cerebellum: involvement in nutritional organization. Physiol. Behav. 54:1993;1063-1067.
26. Molinari M., Petrosini L., Gremoli T. Hemicerebellectomy and motor behaviour in rats. II. Effects of cerebellar lesion performed at different developmental stages. Exp. Brain Res. 82:1990;483-492.
27. Panksepp J. Central metabolic and humoral factors involved in the neural regulation of feeding. Pharmacol. Biochem. Behav. 32:(Suppl. 1):1975;107-119.
28. Parsons L.M., Bower J.M., Gao J.H., Xiong J., Li J., Fox P.T. Lateral cerebellar hemispheres actively support sensory acquisition and discrimination rather than motor control. Learn. Mem. 4:1997;49-62.
29. Pellegrino L.J., Altman J. Effects of differential interference with postnatal cerebellar neurogenesis on motor performance, activity level, and maze learning of rats: a developmental study. J. Comp. Physiol. Psychol. 93:1979;1-33.
30. Petrosini L., Molinari M., Gremoli T. Hemicerebellectomy and motor behaviour in rats. I. Development of motor function after neonatal lesion. Exp. Brain Res. 82:1990;472-482.
31. Rondi-Reig L., Delhaye-Bouchaud N., Mariani J., Caston J. Role of the inferior olivary complex in motor skills and motor learning in the adult rat. Neuroscience. 77:1997;955-963.
32. Scalera G. Effects of corticocerebellar lesions on taste preferences, body weight gain, food and fluid intake in the rat. J. Physiol. (Paris). 85:1991;214-222.
33. Shibuki K., Gomi H., Chen L., Bao S., Kim J.J., Wakatsuki H., Fujisaki T., Fujimoto K., Katoh A., Ikeda T., Chen C., Thompson R.F., Itohara S. Deficient cerebellar long-term depression, impaired eyeblink conditioning, and normal motor co-ordination in GFAP mutant mice. Neuron. 16:1996;587-599.
34. Silverman J., Muir W.W. III. A review of laboratory animal anesthesia with chloral hydrate and chloralose. Lab. Anim. Sci. 43:1993;210-216.
35. Vachon P., Faubert S., Blais D., Comtois A., Bienvenu J.G. A pathophysiological study of abdominal organs following intraperitoneal injections of chloral hydrate in rats: comparison between two anaesthesia protocols. Lab. Anim. 34:2000;84-90.
36. Zion C., Auvray N., Caston J., Reber A., Stelz T. Effects of cerebellectomy at day 15 on the ontogenesis of the equilibrium behavior in the rat. Brain Res. 515:1990;104-110.