Regulation of dihydropyridine-sensitive Ca2+ channels during naloxone-induced opioid supersensitivity in rats

European Journal of Pharmacology

Volumn 451, Issue 3, 2002, Pages 271-277

  Gullapalli, Srinivas ^a   Ramarao, Poduri ^a  

^a NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH NIPER   (India)

Author keywords

Analgesia; Bmax; Morphine; Naloxone; Nimodipine; Supersensitivity; Tail flick test; 3H PN200 110 binding

Indexed keywords

CALCIUM CHANNEL L TYPE; DIHYDROPYRIDINE; ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; ISRADIPINE; MORPHINE; NALOXONE; NIMODIPINE; OPIATE;

ANALGESIA; ANIMAL TISSUE; ARTICLE; BINDING ASSAY; BRAIN MEMBRANE; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; DRUG POTENTIATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SUPERSENSITIVITY; TAIL FLICK TEST;

ANALGESIA; ANIMALS; BRAIN; CALCIUM CHANNEL BLOCKERS; DRUG INTERACTIONS; ENKEPHALIN, ALA(2)-MEPHE(4)-GLY(5)-; ISRADIPINE; MALE; MORPHINE; NALOXONE; NIMODIPINE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, OPIOID, MU;

EID: 0037144180     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(02)02153-2     Document Type: Article

References (28)

1. 2+ antagonists. Pharmacol. Res. Commun. 16:1984;1009-1018.
2. Carta F., Bianchi M., Argenton S., Cervi D., Marolla G., Tamburini M., Breda M., Fantoni A., Panerai A.E. Effect of nifedipine on morphine-induced analgesia. Anesth. Analg. 70:1990;493-498.
3. Chapman D.B., Way E.L. Metal ion interactions with opiates. Annu. Rev. Pharmacol. Toxicol. 20:1980;553-579.
4. 2+ channel antagonists increase morphine induced analgesia and antagonize morphine tolerance. Eur. J. Pharmacol. 148:1988;463-466.
5. D'Amour F.E., Smith D.L. A method for determining loss of pain sensation. J. Pharmacol. Exp. Ther. 72:1941;74-79.
6. 3H)Tyr-D-Ser-Gly-Phe-Leu-Thr: a specific probe for the δ-opiate receptor subtype in brain membrane. Eur. J. Pharmacol. 78:1982;385-387.
7. 2+ channels during opioid tolerance and supersensitivity in rats. J. Pharmacol. Exp. Ther. 274:1995;1538-1544.
8. Diaz A., Ruiz F., Florez J., Hurle M.A., Pazos A. Mu-opioid receptor regulation during opioid tolerance and supersensitivity in rat central nervous system. J. Pharmacol. Exp. Ther. 274:1995;1545-1551.
9. Dierssen M.M., Florez J., Hurle M.A. Calcium channel modulation by dihydropyridines modifies sufentanil-induced antinociception in acute and tolerant conditions. Naunyn-Schmiedeberg's Arch. Pharmacol. 342:1990;559-565.
10. 2+ channel modulation by dihydropyridines potentiates κ-opioid receptor agonist induced acute analgesia and inhibits development of tolerance in rats. Neuropharmacology. 42:2002;467-475.
11. 2+ channels in attenuated morphine antinociception in streptozotocin-diabetic rats. Eur. J. Pharmacol. 435:2002;187-194.
12. 2+ ion in the morphine analgesia. Jpn. J. Pharmacol. 14:1964;227-229.
13. Harris R.A., Loh H.H., Way E.L. Effects of divalent cations, cation chelators and an ionophore on morphine analgesia and tolerance. J. Pharmacol. Exp. Ther. 195:1975;488-498.
14. Lahti R.A., Collins R.J. Chronic naloxone results in a prolonged increase in opiate binding sites in brain. Eur. J. Pharmacol. 51:1978;185-186.
15. Lee S.C., Yoburn B.C. The effect of nimodipine on opioid antagonist-induced upregulation and supersensitivity. Pharmacol. Biochem. Behav. 66:2000;347-351.
16. Lowry O.H., Rosebrough N.F., Farr A.L., Randall R.J. Protein measurement with folin phenol reagent. J. Biol. Chem. 193:1951;265-275.
17. 2+ channel antagonists on morphine analgesia, tolerance and dependence, and on blood pressure in the rat. Eur. J. Pharmacol. 352:1998;189-197.
18. Morris B.J., Millan M.J., Herz A. Antagonist-induced opioid receptor upregulation: II. Regionally specific modulation of mu, delta and kappa binding sites revealed by quantitative autoradiography. J. Pharmacol. Exp. Ther. 247:1988;729-736.
19. Munson P., Rodbard D. Ligand: a versatile computerized approach for characterization of ligand-binding systems. Anal. Biochem. 107:1980;1247-1254.
20. 3H]nitrendipine binding sites in the brain in morphine-tolerant mice. Eur. J. Pharmacol. 102:1984;371-372.
21. Santillan R., Maestre J.M., Hurle M.A., Florez J. Nimodipine-enhanced opiate analgesia in cancer patients requiring morphine dose escalation: a double-blind, placebo-controlled study. Pain. 76:1998;17-26.
22. Smith F.L., Stevens D.L. Calcium modulation of morphine analgesia: role of calcium channels and intracellular pool calcium. J. Pharmacol. Exp. Ther. 272:1995;290-299.
23. Smith F.L., Dombrowski D.S., Dewey W.L. Involvement of intracellular calcium in morphine tolerance in mice. Pharmacol. Biochem. Behav. 62:1999;381-388.
24. Tang A.H., Collins R.J. Enhanced analgesic effect of morphine after chronic administration of naloxone in the rat. Eur. J. Pharmacol. 47:1978;473-474.
25. Tempel A., Zukin R.S., Gardner E.L. Supersensitivity of brain opiate receptor subtypes after chronic naltrexone treatment. Life Sci. 31:1982;1401-1404.
26. Vocci F.J., Welch S.P., Dewey W.L. Differential effects of divalent cations, cation chelators and an ionophore on morphine and dibutyryl guanosine 3′, 5′-cyclic monophosphate antinociception. J. Pharmacol. Exp. Ther. 214:1980;463-466.
27. Yoburn B.C., Goodman R.R., Cohen A.H., Pasternak G.W., Inturrisi C.E. Increased analgesic potency of morphine and increased brain opioid binding sites in the rat following chronic naltrexone treatment. Life Sci. 36:1985;2325-2332.
28. Zukin R.S., Sugarman J.R., Fitz-Syage M.L., Gardner E.L., Zukin S.R., Gintzler A.R. Naltrexone-induced opiate receptor supersensitivity. Brain Res. 245:1982;285-292.