Integration of reactive membrane extraction with lipase-hydrolysis dynamic kinetic resolution of naproxen 2,2,2-trifluoroethyl thioester in isooctane

Biotechnology and Bioengineering

Volumn 79, Issue 2, 2002, Pages 200-210

  Lu, Chu Hsun ^a   Cheng, Yu Chi ^a   Tsai, Shau Wei ^a  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

Author keywords

(S) naproxen; Dynamic kinetic resolution; Lipase; Reactive membrane extraction

Indexed keywords

BIOCATALYSTS; ENZYMES; ESTERS; EXTRACTION; HYDROLYSIS; PH EFFECTS;

RACEMIZATION;

BIOLOGICAL MEMBRANES;

NAPROXEN DERIVATIVE; OCTANE; TRIACYLGLYCEROL LIPASE; 2,2,4 TRIMETHYLPENTANE; 2,2,4-TRIMETHYLPENTANE; AMINE; DRUG DERIVATIVE; IMMOBILIZED ENZYME; NAPROXEN; NAPROXEN 2,2,2 TRIFLUOROETHYL THIOESTER; NAPROXEN 2,2,2-TRIFLUOROETHYL THIOESTER; POLYPROPYLENE; TRI-N-OCTYLAMINE; TRIOCTYLAMINE;

ARTICLE; BIOCATALYST; CHEMICAL REACTION KINETICS; DISSOCIATION; ENANTIOMER; ENZYME ACTIVATION; ENZYME STABILITY; EXTRACTION; HYDROLYSIS; IMMOBILIZATION; MOLECULAR DYNAMICS; NONHUMAN; PARTITION COEFFICIENT; PH MEASUREMENT; STEREOCHEMISTRY; ARTIFICIAL MEMBRANE; CATALYSIS; CHEMICAL MODEL; CHEMISTRY; COMPARATIVE STUDY; COMPUTER SIMULATION; PH; SENSITIVITY AND SPECIFICITY; STEREOISOMERISM; SYNTHESIS;

AMINES; CATALYSIS; COMPARATIVE STUDY; COMPUTER SIMULATION; ENZYMES, IMMOBILIZED; HYDROGEN-ION CONCENTRATION; HYDROLYSIS; MEMBRANES, ARTIFICIAL; MODELS, CHEMICAL; NAPROXEN; OCTANES; POLYPROPYLENES; SENSITIVITY AND SPECIFICITY; STEREOISOMERISM; SUPPORT, NON-U.S. GOV'T;

EID: 0037142780     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/bit.10274     Document Type: Article

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