Synthesis and evaluation of new antimalarial analogues of quinoline alkaloids derived from Cinchona ledgeriana moens ex trimen

Bioorganic and Medicinal Chemistry Letters

Volumn 12, Issue 10, 2002, Pages 1351-1355

  Park, Byeoung Soo ^a   Kim, Dae Young ^a   Rosenthal, Philip J ^b   Huh, Sun Chul ^a   Lee, Belinda J ^b   Park, Eun Ju ^a   Kim, Sung Min ^a   Kim, Jang Eok ^c   Kim, Mi Hee ^a   Huh, Tae Lin ^c   Choi, Young Jae ^a   Suh, Ki Hyung ^a   Choi, Won Sik ^a   Lee, Sung Eun ^c  

^a Soonchunhyang University   (South Korea)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c Kyungpook National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALOID; ANTIMALARIAL AGENT; CINCHONIDINE; N (3,5 DI TERT BUTYL 4 METHOXYBENZYL)QUININIUM BROMIDE; N (4 METHOXY 3,5 DI TERT BUTYLBENZYL)CINCHONIDINIUM BROMIDE; O BENZYL N (3,5 DI TERT BUTYL 4 METHOXYBENZYL)CINCHONIDINIUM BROMIDE; OSL 14; OSL 5; OSL 7; QUININE; QUINOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIMALARIAL ACTIVITY; ARTICLE; CINCHONA; CONTROLLED STUDY; DRUG ACTIVITY; DRUG POTENCY; DRUG SCREENING; DRUG SYNTHESIS; NONHUMAN; PLASMODIUM FALCIPARUM; STRUCTURE ANALYSIS;

ANIMALS; ANTIMALARIALS; CHLOROQUINE; CINCHONA ALKALOIDS; DRUG DESIGN; DRUG RESISTANCE; ERYTHROCYTES; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR CONFORMATION; PLASMODIUM; QUINOLINES; STRUCTURE-ACTIVITY RELATIONSHIP;

CINCHONA; CINCHONA CALISAYA; PLASMODIUM FALCIPARUM;

EID: 0037140882     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(02)00173-7     Document Type: Article

References (15)