Optimization of L-phenylalanine production of Corynebacterium glutamicum under product feedback inhibition by elevated oxygen transfer rate

Biotechnology and Bioengineering

Volumn 77, Issue 2, 2002, Pages 131-141

  Shu, Chin Hang ^a   Liao, Chii Cherng ^b  

^a NATIONAL CENTRAL UNIVERSITY   (Taiwan)

^b FOOD INDUSTRY RESEARCH AND DEVELOPMENT INSTITUTE   (Taiwan)

Author keywords

Corynebacterium glutamicum; Oxygen supply; Phenylalanine; Product inhibition

Indexed keywords

CELLS; ENZYME INHIBITION; FERMENTATION; GROWTH KINETICS; OXYGEN;

CELL GROWTH;

AMINO ACIDS;

PHENYLALANINE;

ARTICLE; BACTERIUM CULTURE; BIOMASS FERMENTATION; CORYNEBACTERIUM GLUTAMICUM; CULTURE MEDIUM; FERMENTATION TECHNIQUE; KINETICS; NONHUMAN; OXYGEN SUPPLY;

CORYNEBACTERIUM; FEEDBACK; FERMENTATION; OXYGEN; PHENYLALANINE;

CHAETODON; CORYNEBACTERIUM; CORYNEBACTERIUM GLUTAMICUM;

EID: 0037137888     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/bit.10125     Document Type: Article

References (29)

1. Effect of oxygen supply on L-phenylalanine, L-proline, L-glutamine and L-arginine fermentations
2. Effect of oxygen supply on L-lysine, L-threonine and L-isoleucine fermentations
3. Genetic engineering of metabolic pathways applied to the production of phenylalanine
4. Fermentation exhaust gas analysis using mass spectrometry
5. Cloning of m-fluorophenylalanine resistant gene and mutational analysis of feekback-resistant prephenate dehydratase from Corynebaterium glutamicum
6. Continuous production of phenylalanine using an Escherichia coli regulatory mutant
7. Phenylalanine production from recombinant Escherichia coli strain in fed-batch culture
8. Pilot-scale production of L-phenylalanine from D-glucose
9. L-Tyrosine production by analogue-resistant mutants derived from a phenylalanine auxotrophy of Corynebacterium glutamicum
10. L-Phenylalanine production by analogue resistant mutants of Corynebacterium glutamicum
11. The biosynthetic control in aromatic amino acid producing mutants of Corynebacterium glutamicum
12. L-tryptophan production by analogue-resistant derived from a phenylalanine and tyrosine double auxotroph of Corynebacterium glutamicum
13. Biochemical effects of oxygen supply and carbon dioxide removal
14. The fermentation process of L-phenylalanine production using an auxotrophic regulatory mutant of Escherichia coli
15. Molecular breeding of a Brevibacterium lactofermentum L-phenylalanine producer using a cloned prephenate dehydratase gene
16. Metabolic engineering to produce tyrosine or phenylalanine in a tryptophan-producing Corynebacterium glutamicum strain
17. A balanced DO-stat and its application to the control of acetic acid excretion by recombinant Escherichia coli
18. Physiologically motivated strategies for control of the fed-batch cultivation of recombinant Escherichia coli for phenylalanine production
19. Changes in yeast amino acid pool with respiratory versus fermentative metabolism
20. Studies on the rate of lysine production by Brevibacterium lactofermentum from glucose
21. Cloning of the genes concerned in phenylalanine biosynthesis in Corynebacterium glutamicum and its application to breeding of a phenylalanine producing strain
22. Phenylalanine production by periodic induction of gene expression using a temperature-distributed dual fermentor system
23. Regulation of aromatic amino acid biosynthesis and production of tyrosine and phenylalanine in Brevibacterium flavum
24. Expression of pheA gene using PR-PI tandem promoter of bacteriophage lambda
25. Control of L-phenylalanine production by dual feeding of glucose and L-tyrosine
26. Amino acid biosynthesis and its regulation
27. An useful substrate feeding strategy - Oxystat for L-phenylalanine fermentation by Corynebacterium glutamicum
28. Increased phenylalanine production by growing and non-growing Escherichia coli strain CWML2