Nuclear distribution of porphobilinogen deaminase (PBGD) in glioma cells: A regulatory role in cancer transformation?

British Journal of Cancer

Volumn 86, Issue 6, 2002, Pages 1006-1011

  Greenbaum, L ^a   Gozlan, Y ^a   Schwartz, D ^a   Katcoff, D J ^a   Malik, Z ^a  

^a BAR ILAN UNIVERSITY   (Israel)

Author keywords

Differentiation; Glioma c6; Porphobilinogen deaminase; Protoporphyrin

Indexed keywords

GREEN FLUORESCENT PROTEIN; PORPHOBILINOGEN DEAMINASE;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL ACTIVITY; CELL CYCLE G1 PHASE; CELL DIFFERENTIATION; CELLULAR DISTRIBUTION; ENZYME ACTIVITY; GLIOMA CELL; IMMUNOLOCALIZATION; MALIGNANT TRANSFORMATION; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT; REGULATORY MECHANISM; WESTERN BLOTTING;

ANIMALS; CELL NUCLEUS; CELL TRANSFORMATION, NEOPLASTIC; GLIOMA; HYDROXYMETHYLBILANE SYNTHASE; RATS; TUMOR CELLS, CULTURED;

EID: 0037128670     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjc.6600173     Document Type: Article

References (41)

1. Autofluorescence imaging and spectroscopy of normal and malignant mucosa in patients with head and neck cancer
2. Differentiation-related mechanisms which suppress DNA replication
3. Regulation of the G1 phase of the mammalian cell cycle
4. A regulatory role for porphobilinogen deaminase (PBGD) in delta-aminolaevulinic acid (deha-ALA)-induced photosensitization?
5. 240-kDa proteasome inhibitor (CF-2) is identical to delta-aminolevulinic acid dehydratase
6. Effect of delta-aminolevulinic acid on protoporphyrin IX accumulation in tumor cells transfected with plasmids containing porphobilinogen deaminase DNA
7. Assessment of 5-aminolevulinic acid-induced porphyrin fluorescence in patients with peritoneal endometriosis
8. Biochemical basis of 5-aminolaevulinic acid-induced protoporphyrin IX accumulation: A study in patients with (pre)malignant lesions of the oesophagus
9. Porphyrin biosynthesis in human Barrett's oesophagus and adenocarcinoma after ingestion of 5-aminolaevulinic acid
10. Activity and immunohistochemical localization of porphobilinogen deaminase in rat tissues
11. Endogenous protoporphyrin IX, a clinically useful photosensitizer for 5-Aminolevulinic acid-based photodynamic therapy: Principles and experimental research
12. Photodynamic therapy with endogenous protoporphyrin IX: Basic principles and present clinical experience
13. Heme-biosynthetic enzyme activities and porphyrin accumulation in normal liver and hepatoma cell line of rats
14. Detection of early bladder cancer by 5-aminolevulinic acid induced porphyrin fluorescence
15. 5-Aminolevulinic acid-induced fluorescence endoscopy for the detection of lower urinary tract tumors
16. Activity of porphobilinogen deaminase in peripheral blood mononuclear cells of patients with metastatic cancer
17. Initial experience in the treatment of oral leukoplakia with high-dose vitamin A and follow-up 5-aminolevulinic acid induced protoporphyrin IX fluorescence
18. A pilot series demonstrating fluorescence staining of laryngeal papilloma using 5-aminolevulinic acid
19. Motor neuropathy in porphobilinogen deaminase-deficient mice imitates the peripheral neuropathy of human acute porphyria
20. Imaging of human skin lesions using multipixel Fourier transform spectroscopy
21. Fourier transform multipixel spectroscopy and spectral imaging of protoporphyrin and Photofrin in single melanoma cells
22. Inactivation of erythropoietic, lymphopoietic and myelocytic leukemic cells by photoexcitation of endogenous porphyrins
23. Destruction of erythroleukemic cells by photoactivation of endogenous porphyrins
24. Multiple biological responses activated by nuclear protein kinase
25. Photodynamic therapy of cutaneous lymphoma using 5-aminolevulinic acid topical application
26. The kinetics of protoporphyrin fluorescence during ALA-PDT in human malignant skin tumors
27. Temperature monitoring during photodynamic therapy of skin tumors with topical 5-aminolevulinic acid application
28. Photodynamic therapy of malignant lesions of the skin mediated by topical application of 5-aminolevulinic acid in combination with DMSO and EDTA
29. Transdifferentiation of C6 glial cells in culture
30. 5-Aminolevulinic acid-based photodynamic therapy. Clinical photodynamic therapy
31. 5-Aminolevulinic acid-based photodynamic therapy. Clinical research and future challenges
32. Lens crystallins. Innovation associated with changes in gene regulation
33. Porphyrin porphobilinogen and amino ketone levels in tumor tissue
34. Nucleoside diphosphate kinase (Nm23-R1/NDPK) is associated with intermediate filaments and becomes upregulated upon camp induced differentiation of rat C6 glioma
35. Regulation of the genes for heme pathway enzymes in erythroid and in non-erythroid cells
36. Growth rate determines activity of porphobilinogen deaminase both in nonmalignant and malignant cell lines
37. Cylic AMP decreases the expression of a neuronal marker (GAD 67) and increases the expression of an astroglial marker (GFAP) in C6 cells
38. Fluorescence endoscopy of gastrointestinal diseases: Basic principles, techniques, and clinical experience
39. Technical principles for protoporphyrin-IX-fluorescence guided microsurgical resection of malignant glioma tissue
40. Intraoperative detection of malignant gliomas by 5-aminolevulinic acid induced porphyrin fluorescence
41. Cell growth suppression of astrocytoma C6 cells by glial fibrillary acidic protein cDNA transfection