메뉴 건너뛰기




Volumn 140, Issue 6, 1998, Pages 1395-1405

Processivity of the motor protein kinesin requires two heads

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; KINESIN;

EID: 0032559822     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.140.6.1395     Document Type: Article
Times cited : (251)

References (44)
  • 2
    • 0028899953 scopus 로고
    • Failure of a single-headed kinesin to track parallel to microtubule protofilaments
    • Berliner, E., E.C. Young, K. Anderson, U.K. Mahtani, and J. Gelles. 1995. Failure of a single-headed kinesin to track parallel to microtubule protofilaments. Nature. 373:718-721.
    • (1995) Nature , vol.373 , pp. 718-721
    • Berliner, E.1    Young, E.C.2    Anderson, K.3    Mahtani, U.K.4    Gelles, J.5
  • 3
    • 0025222347 scopus 로고
    • Bead movement by single kinesin molecules studied with optical tweezers
    • Block, S.M., L.S. Goldstein, and B.J. Schnapp. 1990. Bead movement by single kinesin molecules studied with optical tweezers. Nature. 348:348-352.
    • (1990) Nature , vol.348 , pp. 348-352
    • Block, S.M.1    Goldstein, L.S.2    Schnapp, B.J.3
  • 4
    • 0029449733 scopus 로고
    • Motor proteins 1: Kinesins
    • Bloom, G.S., and S.A. Endow. 1995. Motor proteins 1: kinesins. Protein Profile. 2:1105-1171.
    • (1995) Protein Profile , vol.2 , pp. 1105-1171
    • Bloom, G.S.1    Endow, S.A.2
  • 5
    • 0023944514 scopus 로고
    • Native structure and physical properties of bovine brain kinesin and identification of the ATP-binding subunit polypeptide
    • Bloom, G.S., M.C. Wagner, K.K. Pfister, and S.T. Brady. 1988. Native structure and physical properties of bovine brain kinesin and identification of the ATP-binding subunit polypeptide. Biochemistry. 27:3409-3416.
    • (1988) Biochemistry , vol.27 , pp. 3409-3416
    • Bloom, G.S.1    Wagner, M.C.2    Pfister, K.K.3    Brady, S.T.4
  • 7
    • 0028917410 scopus 로고
    • Sedimentation studies on the kinesin motor domain constructs K401, K366, and K341
    • Correia, J.J., S.P. Gilbert, M.L. Moyer, and K.A. Johnson. 1995. Sedimentation studies on the kinesin motor domain constructs K401, K366, and K341. Biochemistry. 34:4898-1907.
    • (1995) Biochemistry , vol.34 , pp. 4898-11907
    • Correia, J.J.1    Gilbert, S.P.2    Moyer, M.L.3    Johnson, K.A.4
  • 8
  • 9
    • 0027533269 scopus 로고
    • Flexural rigidity of microtubules and actin filaments measured from thermal fluctuations in shape
    • Gittes, F., B. Mickey, J. Nettleton, and J. Howard. 1993. Flexural rigidity of microtubules and actin filaments measured from thermal fluctuations in shape. J. Cell Biol. 120:923-934.
    • (1993) J. Cell Biol. , vol.120 , pp. 923-934
    • Gittes, F.1    Mickey, B.2    Nettleton, J.3    Howard, J.4
  • 10
    • 1542353988 scopus 로고
    • Kinesin ATPasc: Rate limiting ADP release
    • Hackney, D.D. 1988. Kinesin ATPasc: Rate limiting ADP release. Proc. Natl. Acad. Sci. USA. 85:6314-6318.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 6314-6318
    • Hackney, D.D.1
  • 11
    • 0028200793 scopus 로고
    • Evidence for alternating head catalysis by kinesin during microtubule-stimulated ATP hydrolysis
    • Hackney, D.D. 1994. Evidence for alternating head catalysis by kinesin during microtubule-stimulated ATP hydrolysis. Proc. Natl. Acad. Sci. USA. 91: 6865-6869.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 6865-6869
    • Hackney, D.D.1
  • 12
    • 0029156511 scopus 로고
    • Highly processive microtubule-stimulated ATP hydrolysis by dimeric kinesin head domains
    • Hackney, D.D. 1995. Highly processive microtubule-stimulated ATP hydrolysis by dimeric kinesin head domains. Nature. 377:448-450.
    • (1995) Nature , vol.377 , pp. 448-450
    • Hackney, D.D.1
  • 14
    • 0001145764 scopus 로고
    • The combination of hemoglobin with oxygen and with carbon monoxide
    • Hill, A.V. 1913. The combination of hemoglobin with oxygen and with carbon monoxide. Biochem. J. 7:471-480.
    • (1913) Biochem. J. , vol.7 , pp. 471-480
    • Hill, A.V.1
  • 15
    • 0024591237 scopus 로고
    • Submolecular domains of bovine brain kinesin identified by electron microscopy and monoclonal antibody decoration
    • Hirokawa, N., K.K. Pfister, H. Yorifuji, M.C. Wagner, S.T. Brady, and G.S. Bloom. 1989. Submolecular domains of bovine brain kinesin identified by electron microscopy and monoclonal antibody decoration. Cell. 56:867-878.
    • (1989) Cell , vol.56 , pp. 867-878
    • Hirokawa, N.1    Pfister, K.K.2    Yorifuji, H.3    Wagner, M.C.4    Brady, S.T.5    Bloom, G.S.6
  • 16
    • 0029960345 scopus 로고    scopus 로고
    • The movement of kinesin along microtubules
    • Howard, J. 1996. The movement of kinesin along microtubules. Annu. Rev. Physiol. 58:703-729.
    • (1996) Annu. Rev. Physiol. , vol.58 , pp. 703-729
    • Howard, J.1
  • 17
    • 0030773824 scopus 로고    scopus 로고
    • Molecular motors: Structural adaptations to cellular functions
    • Howard, J. 1997. Molecular motors: structural adaptations to cellular functions. Nature. 389:561-567.
    • (1997) Nature , vol.389 , pp. 561-567
    • Howard, J.1
  • 18
    • 0027728131 scopus 로고
    • Preparation of marked microtubules for the assay of the polarity of microtubule-based motors by fluorescence microscopy
    • Howard, J., and A.A. Hyman. 1993. Preparation of marked microtubules for the assay of the polarity of microtubule-based motors by fluorescence microscopy. Methods Cell Biol. 39:105-113.
    • (1993) Methods Cell Biol. , vol.39 , pp. 105-113
    • Howard, J.1    Hyman, A.A.2
  • 19
    • 0024463944 scopus 로고
    • Movement of microtubules by single kinesin molecules
    • Howard, J., A.J. Hudspeth, and R.D. Vale. 1989. Movement of microtubules by single kinesin molecules. Nature. 342:154-158.
    • (1989) Nature , vol.342 , pp. 154-158
    • Howard, J.1    Hudspeth, A.J.2    Vale, R.D.3
  • 20
    • 0027736955 scopus 로고
    • Assay of microtubule movement driven by single kinesin molecules
    • Howard, J., A.J. Hunt, and S. Baek. 1993. Assay of microtubule movement driven by single kinesin molecules. Methods Cell Biol. 39:137-147.
    • (1993) Methods Cell Biol. , vol.39 , pp. 137-147
    • Howard, J.1    Hunt, A.J.2    Baek, S.3
  • 21
    • 0030844286 scopus 로고    scopus 로고
    • Coupling of kinesin steps to ATP hydrolysis
    • Hua, W., E.C. Young, M.L. Fleming, and J. Gelles. 1997. Coupling of kinesin steps to ATP hydrolysis. Nature. 388:390-393.
    • (1997) Nature , vol.388 , pp. 390-393
    • Hua, W.1    Young, E.C.2    Fleming, M.L.3    Gelles, J.4
  • 22
    • 0028363764 scopus 로고
    • Drosophila kinesin minimal motor domain expressed in Escherichia coli
    • Huang, T., and D.D. Hackney. 1994. Drosophila kinesin minimal motor domain expressed in Escherichia coli. J. Biol. Chem. 269:16493-16501.
    • (1994) J. Biol. Chem. , vol.269 , pp. 16493-16501
    • Huang, T.1    Hackney, D.D.2
  • 23
    • 0028363765 scopus 로고
    • Drosophila kinesin motor domain extending to amino acid position 392 is dimeric when expressed in Escherichia coli
    • Huang, T.G., J. Suhan, and D.D. Hackney. 1994. Drosophila kinesin motor domain extending to amino acid position 392 is dimeric when expressed in Escherichia coli. J. Biol. Chem. 269:16502-16507.
    • (1994) J. Biol. Chem. , vol.269 , pp. 16502-16507
    • Huang, T.G.1    Suhan, J.2    Hackney, D.D.3
  • 24
    • 0027133242 scopus 로고
    • Kinesin swivels to permit microtubule movement in any direction
    • Hunt, A.J., and J. Howard. 1993. Kinesin swivels to permit microtubule movement in any direction. Proc. Natl. Acad. Sci. USA. 90:11653-11657.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 11653-11657
    • Hunt, A.J.1    Howard, J.2
  • 27
    • 0029989974 scopus 로고    scopus 로고
    • Crystal structure of the kinesin motor domain reveals a structural similarity to myosin
    • Kull, F.J., E.P. Sahlin, R. Lau, R.J. Fletterick, and R.D. Vale. 1996. Crystal structure of the kinesin motor domain reveals a structural similarity to myosin. Nature. 380:550-555.
    • (1996) Nature , vol.380 , pp. 550-555
    • Kull, F.J.1    Sahlin, E.P.2    Lau, R.3    Fletterick, R.J.4    Vale, R.D.5
  • 28
    • 0027426228 scopus 로고
    • Skeletal muscle myosin light chains are essential for physiological speeds of shortening
    • Lowey, S., G.S. Waller, and K.M. Trybus. 1993. Skeletal muscle myosin light chains are essential for physiological speeds of shortening. Nature. 365:454-456.
    • (1993) Nature , vol.365 , pp. 454-456
    • Lowey, S.1    Waller, G.S.2    Trybus, K.M.3
  • 29
    • 0031021473 scopus 로고    scopus 로고
    • Interacting head mechanism of microlubule-kinesin ATPase
    • Ma, Y.Z., and E.W. Taylor. 1997. Interacting head mechanism of microlubule-kinesin ATPase. J. Biol. Chem. 272:724-730.
    • (1997) J. Biol. Chem. , vol.272 , pp. 724-730
    • Ma, Y.Z.1    Taylor, E.W.2
  • 30
    • 0028843342 scopus 로고
    • The force generated by a single kinesin molecule against an elastic load
    • Meyhöfer, E., and J. Howard. 1995. The force generated by a single kinesin molecule against an elastic load. Proc. Natl. Acad. Sci. USA. 92:574-578.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 574-578
    • Meyhöfer, E.1    Howard, J.2
  • 31
    • 0028641560 scopus 로고
    • KIF1B, a novel microtubule plus end-directed monomeric motor protein for transport of mitochondria
    • Nangaku, M., Y.-R. Sato, Y. Okada, Y. Noda, R. Takemura, H. Yamazaki, and N. Hirokawa. 1994. KIF1B, a novel microtubule plus end-directed monomeric motor protein for transport of mitochondria. Cell. 79:1209-1220.
    • (1994) Cell , vol.79 , pp. 1209-1220
    • Nangaku, M.1    Sato, Y.-R.2    Okada, Y.3    Noda, Y.4    Takemura, R.5    Yamazaki, H.6    Hirokawa, N.7
  • 32
    • 0029051298 scopus 로고
    • The neuron-specific kinesin superfamily protein KIF1A is a unique monomeric motor for anterograde axonal transport of synaptic vesicle precursors
    • Okada, Y., H. Yamazaki, A.-Y. Sekine, and N. Hirokawa. 1995. The neuron-specific kinesin superfamily protein KIF1A is a unique monomeric motor for anterograde axonal transport of synaptic vesicle precursors. Cell. 81:769-780.
    • (1995) Cell , vol.81 , pp. 769-780
    • Okada, Y.1    Yamazaki, H.2    Sekine, A.-Y.3    Hirokawa, N.4
  • 33
    • 0027211908 scopus 로고
    • Kinesin follows the microtubule's protofilament axis
    • Ray, S., E. Meyhöfer, R.A. Milligan, and J. Howard. 1993. Kinesin follows the microtubule's protofilament axis. J. Cell Biol. 121:1083-1093.
    • (1993) J. Cell Biol. , vol.121 , pp. 1083-1093
    • Ray, S.1    Meyhöfer, E.2    Milligan, R.A.3    Howard, J.4
  • 34
    • 0025647064 scopus 로고
    • Delayed start-up of kinesin-driven microtubule gliding following inhibition hy adenosine 5′-[β,γ-imido]triphosphate
    • Schnapp, B.J., B. Crise, M.P. Sheetz, T.S. Reese, and S. Khan. 1990. Delayed start-up of kinesin-driven microtubule gliding following inhibition hy adenosine 5′-[β,γ-imido]triphosphate. Proc: Natl. Acad. Sci. USA. 87:10053-10057.
    • (1990) Proc: Natl. Acad. Sci. USA , vol.87 , pp. 10053-10057
    • Schnapp, B.J.1    Crise, B.2    Sheetz, M.P.3    Reese, T.S.4    Khan, S.5
  • 35
    • 0030744142 scopus 로고    scopus 로고
    • Kinesin hydrolyzes one ATP per 8-nm step
    • Schnitzer, M.J., and S.M. Block. 1997. Kinesin hydrolyzes one ATP per 8-nm step. Nature. 388:386-390.
    • (1997) Nature , vol.388 , pp. 386-390
    • Schnitzer, M.J.1    Block, S.M.2
  • 36
    • 0027405349 scopus 로고
    • Recombinant kinesin motor domain binds to β tubulin and decorates microtubules with a B surface lattice
    • Sung, Y.-H., and E. Mandelkow. 1993. Recombinant kinesin motor domain binds to β tubulin and decorates microtubules with a B surface lattice. Proc. Natl. Acad. Sci. USA. 90:1671-1675.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 1671-1675
    • Sung, Y.-H.1    Mandelkow, E.2
  • 37
    • 0027279053 scopus 로고
    • Direction of microtubule movement is an intrinsic property of the motor domains of kinesin heavy chain und Drosophila ncd protein
    • Stewart, R.J., J.P. Thaler, and L.S. Goldstein. 1993. Direction of microtubule movement is an intrinsic property of the motor domains of kinesin heavy chain und Drosophila ncd protein. Proc. Natl. Acad. Sci. USA. 90:5209-5213.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 5209-5213
    • Stewart, R.J.1    Thaler, J.P.2    Goldstein, L.S.3
  • 38
    • 0028362896 scopus 로고
    • Force and velocity measured for single kinesin molecules
    • Svoboda, K., and S.M. Block. 1994. Force and velocity measured for single kinesin molecules. Cell. 77:773-784.
    • (1994) Cell , vol.77 , pp. 773-784
    • Svoboda, K.1    Block, S.M.2
  • 39
    • 0027453868 scopus 로고
    • Direct observation of kinesin stepping by optical trapping interferometry
    • Svoboda, K., C.F. Schmidt, B.J. Schnapp, and S.M. Block. 1993. Direct observation of kinesin stepping by optical trapping interferometry. Nature. 365:721-727.
    • (1993) Nature , vol.365 , pp. 721-727
    • Svoboda, K.1    Schmidt, C.F.2    Schnapp, B.J.3    Block, S.M.4
  • 40
    • 0029913456 scopus 로고    scopus 로고
    • The neck region of the myosin motor domain acts as a lever arm to generate movement
    • Uyeda, T.Q., P.D. Ahramson, and J.A. Spudich. 1996. The neck region of the myosin motor domain acts as a lever arm to generate movement. Proc. Natl. Acad. Sci. USA. 93:4459-1464.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 4459-11464
    • Uyeda, T.Q.1    Ahramson, P.D.2    Spudich, J.A.3
  • 41
    • 0029879228 scopus 로고    scopus 로고
    • Direct observation of single kinesin molecules moving along microtubules
    • Vale, R.D., T. Funatsu, D.W. Pierce, L. Romberg, Y. Harada, and T. Yanagida. 1996. Direct observation of single kinesin molecules moving along microtubules. Nature. 380:415-453.
    • (1996) Nature , vol.380 , pp. 415-453
    • Vale, R.D.1    Funatsu, T.2    Pierce, D.W.3    Romberg, L.4    Harada, Y.5    Yanagida, T.6
  • 42
    • 0024550571 scopus 로고
    • A three-domain structure of kinesin heavy chain revealed by DNA sequence and microtubule binding analyses
    • Yang, J.T., R.A. Laymon, and L.S. Goldstein. 1989. A three-domain structure of kinesin heavy chain revealed by DNA sequence and microtubule binding analyses. Cell. 56:879-889.
    • (1989) Cell , vol.56 , pp. 879-889
    • Yang, J.T.1    Laymon, R.A.2    Goldstein, L.S.3
  • 43
    • 0025362646 scopus 로고
    • Evidence that the head of kinesin is sufficient for force generation and motility in vitro
    • Yang, J.T., W.M. Saxton, R.J. Stewart, E.C. Raff, and L.S. Goldstein. 1990. Evidence that the head of kinesin is sufficient for force generation and motility in vitro. Science. 249:42-17.
    • (1990) Science , vol.249 , pp. 42-117
    • Yang, J.T.1    Saxton, W.M.2    Stewart, R.J.3    Raff, E.C.4    Goldstein, L.S.5
  • 44
    • 0028928670 scopus 로고
    • Subunit interactions in dimeric kinesin heavy chain derivatives that lack the kinesin rod
    • Young, E.C., E. Berliner, H.K. Mahtani, B. Perez-Ramirez, and J. Gelles. 1995. Subunit interactions in dimeric kinesin heavy chain derivatives that lack the kinesin rod. J. Biol. Chem. 270:3926-3931.
    • (1995) J. Biol. Chem. , vol.270 , pp. 3926-3931
    • Young, E.C.1    Berliner, E.2    Mahtani, H.K.3    Perez-Ramirez, B.4    Gelles, J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.