A polymorphism within intron 11 of the tau gene is not increased in frequency in patients with sporadic Alzheimer's disease, nor does it influence the extent of tau pathology in the brain

Neuroscience Letters

Volumn 324, Issue 2, 2002, Pages 113-116

  Green, E K ^a   Thaker, U ^b   McDonagh, A M ^b   Iwatsubo, T ^c   Lambert, J C ^d   Chartier Harlin, M C ^d   Harris, J M ^a   Pickering Brown, S M ^b   Lendon, C L ^a   Mann, D M A ^b,e  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

^c UNIVERSITY OF TOKYO   (Japan)

^d INSTITUT PASTEUR DE LILLE   (France)

^e HOPE HOSPITAL   (United Kingdom)

Author keywords

Apolipoprotein E genotype; Image analysis; Neurofibrillary pathology; Tau gene; Tau haplotypes

Indexed keywords

APOLIPOPROTEIN E; TAU PROTEIN;

ADULT; AGED; ALLELE; ALZHEIMER DISEASE; ARTICLE; AUTOPSY; CONTROLLED STUDY; DISEASE DURATION; DISEASE SEVERITY; DNA POLYMORPHISM; FEMALE; FRONTAL CORTEX; GENE OVEREXPRESSION; GENOTYPE; HAPLOTYPE; HUMAN; HUMAN TISSUE; INTRON; MAJOR CLINICAL STUDY; MALE; MUTATION RATE; NEURITE; NEUROFIBRILLARY TANGLE; NEUROPATHOLOGY; NEUROPIL THREAD; ONSET AGE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

ADULT; AGE OF ONSET; AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; APOLIPOPROTEIN E4; APOLIPOPROTEINS E; BRAIN; DNA MUTATIONAL ANALYSIS; FEMALE; GENE FREQUENCY; GENETIC MARKERS; GENETIC PREDISPOSITION TO DISEASE; GENETIC SCREENING; HAPLOTYPES; HUMANS; INTRONS; LINKAGE DISEQUILIBRIUM; MALE; MIDDLE AGED; MUTATION; NEURONS; POLYMORPHISM, GENETIC; TAU PROTEINS;

EID: 0037123705     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(02)00190-8     Document Type: Article

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