Pick's disease is associated with mutations in the tau gene

Annals of Neurology

Volumn 48, Issue 6, 2000, Pages 859-867

  Pickering Brown, Stuart ^a   Baker, Matt ^f   Yen, Shu Hui ^g   Liu, Wan Kyng ^g   Hasegawa, Masato ^b   Cairns, Nigel ^c   Lantos, Peter L ^c   Rossor, Martin ^c   Iwatsubo, Takeshi ^g   Davies, Yvonne ^d   Allsop, David ^d   Furlong, Rob ^e   Owen, Frank ^a   Hardy, John ^f   Mann, David ^a   Hutton, Mike ^f  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b KING'S COLLEGE LONDON   (United Kingdom)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

^d LANCASTER UNIVERSITY   (United Kingdom)

^e UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^f MAYO CLINIC   (United States)

^g UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; CALPAIN; GLYCINE; LYSINE; TAU PROTEIN; THREONINE;

ADULT; ARTICLE; CLINICAL ARTICLE; CODON; DISEASE ASSOCIATION; DISEASE CLASSIFICATION; ELECTRON MICROSCOPY; FEMALE; FRONTOTEMPORAL DEMENTIA; GENE MUTATION; GENETIC ANALYSIS; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MICROTUBULE ASSEMBLY; PICK PRESENILE DEMENTIA; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION;

EID: 0033669232     PISSN: 03645134     EISSN: None     Source Type: Journal    
DOI: 10.1002/1531-8249(200012)48:6<859::AID-ANA6>3.0.CO;2-1     Document Type: Article

References (20)

1. Frontotemporal lobar degeneration: A consensus on clinical diagnostic criteria
2. Association of missense and 5'-splice-site mutations in tau with the inherited dementia FTDP-17
3. Mutation in the tau gene in familial multisystem tauopathy with presenile dementia
4. Tau is a candidate gene for chromosome 17 frontotemporal dementia
5. Dementia of frontal lobe type - Neuropathology and immunohistochemistry
6. Vulnerable neuronal subsets in Alzheimer's and Pick's disease are distinguished by their τ isoform distribution and phosphorylation
7. Mutation-specific functional impairments in distinct tau isoforms of hereditary FTDP-17
8. Frontotemporal degeneration, Pick disease and corticobasal degeneration: One entity or 3?
9. Frontotemporal degeneration, Pick disease and corticobasal degeneration: One entity or 3?
10. Tau proteins with FTDP-17 mutations have a reduced ability to promote microtubule assembly
11. Tau gene mutation G389R causes a tauopathy with abundant pick body-like inclusions and axonal deposits
12. Protein sequence and mass spectrometric analyses of tau in the Alzheimer's disease brain
13. Heterogeneity of tau proteins in Alzheimer's disease. Evidence for increased expression of an isoform and preferential distribution of a phosphorylated isoform in neurites
14. FTDP-17 tau mutations decrease the susceptibility of tau to calpain I digestion
15. PTL-1, a microtubule-associated protein with tau-like repeats from the nematode Caenorhabditis elegans
16. Frontotemporal dementia and corticobasal degeneration in a family with a P301S mutation in tau
17. New phosphorylation sites identified in hyperphosphorylated tau (paired helical filament-tau) from Alzheimer's disease brain using nanoelectrospray mass spectrometry
18. Tau pathology in two Dutch families with mutations in the microtubule-binding region of tau
19. Frontotemporal dementia and parkinsonism linked to chromosome 17: A consensus conference
20. Fatal familial insomnia and familial Creutzfeldt-Jakob disease: Disease pheno-type determined by a DNA polymorphism