A simplified route to the synthesis of new 99mTc-specific tetradentate ligands

Tetrahedron Letters

Volumn 43, Issue 51, 2002, Pages 9295-9297

  Le Gal, Julien ^a   Benoist, Eric ^a   Gressier, Marie ^a   Coulais, Yvon ^b   Dartiguenave, Michèle ^a  

^a UNIVERSITÉ PAUL SABATIER   (France)

^b CHU PURPAN   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CYSTEINE; LIGAND; TECHNETIUM 99M;

ARTICLE; DRUG SYNTHESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VIVO STUDY; RADIOCHEMISTRY;

EID: 0037121599     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(02)02385-7     Document Type: Article

References (15)

1. Parker D. Chem. Soc. Rev. 19:1990;271-291.
2. Dilworth J.R., Parrot S.J. Chem. Soc. Rev. 27:1998;43-55.
3. Benoist E., Fourteau L., Coulais Y., Dartiguenave M. J. labelled cpd. Radiopharm. 44:2001;S521-S523.
4. Jurisson S., Lydon J.D. Chem. Rev. 99:1999;2205-2218.
5. Fourteau L., Benoist E., Dartiguenave M. Synlett. 1:2001;126-128.
6. De Sousa A.S., Croft G.J.B., Wagner C.A., Mickael J.P., Hancock R.D. Inorg. Chem. 30:1991;3525-3529.
7. De Sousa A.S., Hancock R.D. J. Chem. Soc., Chem. Commun. 1995;415-416.
8. Jackson A.E., Johnstone R.A.W. Synthesis. 1976;685-686.
9. Bermejo M.R., Gonzalez A.M., Fondo M., Garcia-Deibe A., Maneiro M., Sanmartin J., Hoyos O.L., Watkinson M. New J. Chem. 24:2000;235-241.
10. Schneider R.F., Subramanian G., Feld T.A., McAfee J.G., Zapf-longo C., Palladino E., Thomas F.D. J. Nucl. Med. 25:1984;223-229.
11. Bell R.A., Hughes D.W., Lock C.J.L., Valliant J.F. Can. J. Chem. 74:1996;1503-1511.
12. Noveron J.C., Olmstead M.M., Mascharak P.K. J. Am. Chem. Soc. 123:2001;3242-3259.
13. +).
14. 2)=17.00 min. Electrophoresis of each purified complex showed that both are negatively charged complexes.
15. 2)=0.25.