Novel piperidinium and pyridinium agents as water-soluble acetylcholinesterase inhibitors for the reversal of neuromuscular blockade

Bioorganic and Medicinal Chemistry Letters

Volumn 12, Issue 18, 2002, Pages 2569-2572

  Palin, Ronald ^a   Clark, John K ^a   Cowley, Phill ^a   Muir, Alan W ^a   Pow, Eleanor ^a   Prosser, Alan B ^a   Taylor, Robert ^a   Zhang, Ming Qiang ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLINESTERASE INHIBITOR; PIPERIDINIUM; PYRIDINIUM DERIVATIVE; UNCLASSIFIED DRUG; VECURONIUM; WATER;

ANESTHESIA; ARTICLE; CONTROLLED STUDY; DRUG SYNTHESIS; IC 50; IN VITRO STUDY; IN VIVO STUDY; NEUROMUSCULAR BLOCKING; NONHUMAN; SOLUBILITY; SURGICAL TECHNIQUE;

ACETYLCHOLINESTERASE; ANIMALS; CHOLINESTERASE INHIBITORS; CRICETINAE; DIAPHRAGM; NEUROMUSCULAR NONDEPOLARIZING AGENTS; PIPERIDINES; PYRIDINES; SOLUBILITY; VECURONIUM BROMIDE; WATER;

EID: 0037119759     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(02)00483-3     Document Type: Article

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