Highly enantioselective Rh-catalyzed intramolecular Alder-ene reactions for the syntheses of chiral tetrahydrofurans

Angewandte Chemie - International Edition

Volumn 41, Issue 18, 2002, Pages 3457-3460

  Lei, Aiwen ^a   He, Minsheng ^a   Wu, Shulin ^a   Zhang, Xumu ^a  

^a PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

Enantioselectivit; Heterocycles; Homogeneous catalysis; Rhodium; Synthetic methods

Indexed keywords

CATALYSIS; ORGANIC COMPOUNDS; THERMAL EFFECTS;

ROOM TEMPERATURE;

RHODIUM;

FURAN DERIVATIVE; RHODIUM; TETRAHYDROFURAN DERIVATIVE;

ARTICLE; CATALYST; CHEMICAL BOND; CHEMICAL REACTION; CHEMISTRY; CHIRALITY; ENANTIOSELECTIVITY; REACTION ANALYSIS; STEREOISOMERISM; SYNTHESIS; TEMPERATURE DEPENDENCE;

FURANS; RHODIUM; STEREOISOMERISM;

EID: 0037119647     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-3773(20020916)41:18<3457::AID-ANIE3457>3.0.CO;2-3     Document Type: Article

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23. 6 as additive, the reaction of 1a yielded 2a in less than 5% conversion within 20 min at room temperature. This was consistent with the low reactivity observed in ref. [4b].
24. [4] This clearly indicates the differences between our previous catalyst and the new catalytic system.