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Volumn 41, Issue 28, 2002, Pages 8899-8906

DNA adducts formed from 4-hydroxytamoxifen are more mutagenic than those formed by α-acetoxytamoxifen in a shuttle vector target gene replicated in human Ad293 cells

(7) McLuckie, Keith I E a Routledge, Michael N b Brown, Karen a Gaskell, Margaret a Farmer, Peter B a Roberts, Gordon C K c Martin, Elizabeth A a,d

a UNIVERSITY OF LEICESTER (United Kingdom)

b UNIVERSITY OF LEEDS (United Kingdom)

c UNIVERSITY OF LEICESTER (United Kingdom)

d ASTRAZENECA (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

MUTATIONAL HOTSPOTS;

BACTERIA; BIOASSAY; CELLS; DRUG PRODUCTS; GENES; MUTAGENESIS; TISSUE; TUMORS;

DNA;

4 HYDROXYTAMOXIFEN; ALPHA ACETOXYTAMOXIFEN; TAMOXIFEN DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CANCER CELL; CONTROLLED STUDY; DNA ADDUCT; DNA DAMAGE; GENE REPLICATION; HUMAN; HUMAN CELL; MUTAGENICITY; MUTATION; NUCLEIC ACID BASE SUBSTITUTION; PLASMID; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS;

ADENOSINE TRIPHOSPHATE; ANIMALS; BASE SEQUENCE; CARCINOGENS; CELL LINE; CELL SURVIVAL; DNA ADDUCTS; GENES, SUPPRESSOR; GENETIC VECTORS; HUMANS; ISOMERISM; MOLECULAR SEQUENCE DATA; PLASMIDS; RATS; RECOMBINANT PROTEINS; RNA, TRANSFER; TAMOXIFEN;

RODENTIA; UNIDENTIFIED SHUTTLE VECTOR;

EID: 0037118685 PISSN: 00062960 EISSN: None Source Type: Journal
DOI: 10.1021/bi025575i Document Type: Article

Times cited : (22)

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