Cooperative binding of Sox10 to DNA: Requirements and consequences

Nucleic Acids Research

Volumn 30, Issue 24, 2002, Pages 5509-5516

  Schlierf, Beate ^a   Ludwig, Andreas ^a   Klenovsek, Karin ^a   Wegner, Michael ^a  

^a Institut für Biochemie   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; DIMER; DNA; MONOMER; MYELIN PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR SOX10; UNCLASSIFIED DRUG;

ALPHA HELIX; ANIMAL CELL; BINDING SITE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DNA CONFORMATION; GENE TARGETING; GLIA CELL; HIGH MOBILITY GROUP BOX DOMAIN; HUMAN; HUMAN CELL; NEURAL CREST CELL; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA BINDING; PROTEIN FUNCTION; REGULATORY MECHANISM; REVIEW;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; COS CELLS; DNA; DNA-BINDING PROTEINS; ELECTROPHORETIC MOBILITY SHIFT ASSAY; HIGH MOBILITY GROUP PROTEINS; LUCIFERASES; MICE; MOLECULAR SEQUENCE DATA; MUTATION; OLIGONUCLEOTIDES; PROMOTER REGIONS (GENETICS); PROTEIN BINDING; RATS; RECOMBINANT FUSION PROTEINS; REGULATORY SEQUENCES, NUCLEIC ACID; SEQUENCE HOMOLOGY, AMINO ACID; TRANSCRIPTION FACTORS; TUMOR CELLS, CULTURED;

ANIMALIA;

EID: 0037115822     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/gkf690     Document Type: Review

References (24)

1. Bowles,J., Schepers,G. and Koopman,P. (2000) Phylogeny of the SOX family of developmental transcription factors based on sequence and structural indicators. Dev. Biol., 227, 239-255.
2. Wegner,M. (1999) From head to toes: the multiple facets of Sox proteins. Nucleic Acids Res., 27, 1409-1420.
3. Werner,M.H., Huth,J.R., Gronenborn,A.M. and Clore,G.M. (1995) Molecular basis of human 46X,Y sex reversal revealed from the three-dimensional solution strucutre of the human SRY-DNA complex. Cell, 81, 705-714.
4. Giese,K., Cox,J. and Grosschedl,R. (1992) The HMG domain of lymphoid enhancer factor 1 bends DNA and facilitates assembly of functional nucleoprotein structures. Cell, 69, 185-196.
5. Kuhlbrodt,K., Herbarth,B., Sock,E., Hermans-Borgmeyer,I. and Wegner,M. (1998) Sox10, a novel transcriptional modulator in glial cells. J. Neurosci., 18, 237-250.
6. Herbarth,B., Pingault,V., Bondurand,N., Kuhlbrodt,K., Hermans-Borgmeyer,I., Puliti,A., Lemort,N., Goossens,M. and Wegner,M. (1998) Mutation of the Sry-related Sox10 gene in Dominant megacolon, a mouse model for human Hirschsprung disease. Proc. Natl Acad. Sci. USA, 95, 5161-5165.
7. Southard-Smith,E.M., Kos,L. and Pavan,W.J. (1998) Sox10 mutation disrupts neural crest development in Dom Hirschsprung mouse model. Nature Genet., 18, 60-64.
8. Britsch,S., Goerich,D.E., Riethmacher,D., Peirano,R.I., Rossner,M., Nave,K.A., Birchmeier,C. and Wegner,M. (2001) The transcription factor Sox10 is a key regulator of peripheral glial development. Genes Dev., 15, 66-78.
9. Stolt,C.C., Rehberg,S., Ader,M., Lommes,P., Riethmacher,D., Schachner,M., Bartsch,U, and Wegner,M. (2002) Terminal differentiation of myelin-forming oligodendrocytes depends on the transcription factor Sox10. Genes Dev., 16, 165-170.
10. Bondurand,N., Girard,M., Pingault,V., Lemort,N., Dubourg,O. and Goossens,M. (2001) Human Connexin 32, a gap junction protein altered in the X-linked form of Charcot-Marie-Tooth disease, is directly regulated by the transcription factor SOX10. Hum. Mol. Genet., 10, 2783-2795.
11. Peirano,R.I., Goerich,D.E., Riethmacher,D. and Wegner,M. (2000) Protein zero expression is regulated by the glial transcription factor Sox10. Mol. Cell. Biol., 20, 3198-3209.
12. Peirano,R.I. and Wegner,M. (2000) The glial transcription factor Sox10 binds to DNA both as monomer and dimer with different functional consequences. Nucleic Acids Res., 28, 3047-3055.
13. Kuhlbrodt,K., Schmidt,C., Sock,E., Pingault,V., Bondurand,N., Goossens,M. and Wegner,M. (1998) Functional analysis of Sox10 Mutations found in human Waardenburg-Hirschsprung patients. J. Biol. Chem, 273, 23033-23038.
14. Kuhlbrodt,K., Herbarth,B., Sock,E., Enderich,J., Hermans-Borgmeyer,I. and Wegner,M. (1998) Cooperative function of POU proteins and Sox proteins in glial cells. J. Biol. Chem., 273, 16050-16057.
15. Kim,J., Zwieb,C., Wu,C. and Adhya,S. (1989) Bending of DNA by gene-regulatory proteins: construction and use of a DNA bending vector. Gene, 85, 15-23.
16. Sock,E., Renner,K., Feist,D., Leger,H. and Wegner,M. (1996) Functional comparison of PML-type and archetype strains of JC virus. J. Virol., 70, 1512-1520.
17. van Houte,L.P.A., Chuprina,V.P., van der Wetering,M., Boelens,R., Kaptein,R. and Clevers,H. (1995) Solution structure of the sequence-specific HMG box of the lymphocyte transcriptional activator Sox-4. J. Biol. Chem, 270, 30516-30524.
18. Lefebvre,V., Li,P. and de Crombrugghe,B. (1998) A new long form of Sox5 (L-Sox5), Sox6 and Sox9 are coexpressed in chondrogenesis and cooperatively activate the type II collagen gene. EMBO J., 17, 5718-5733.
19. Inoue,K., Tanabe,Y. and Lupski,J.R. (1999) Myelin deficiencies in both the central and peripheral nervous system associated with a SOX10 mutation. Ann. Neurol., 46, 313-318.
20. Pingault,V., Bondurand,N., Kuhlbrodt,K., Goerich,D.E., Prehu,M.-O., Puliti,A., Herbarth,B., Hermans-Borgmeyer,I., Legius,E., Matthijs,G., Amiel,J., Lyonnet,S., Ceccherini,I., Romeo,G., Smith,J.C., Read,A.P., Wegner,M. and Goossens,M. (1998) Sox10 mutations in patients with Waardenburg-Hirschsprung disease. Nature Genet., 18, 171-173.
21. Touraine,R.L., Attie-Bitach,T., Manceau,E., Korsch,E., Sarda,P., Pingault,V., Encha-Razavi,F., Pelet,A., Auge,J., Nivelon-Chevailier,A., Holschneider,A.M., Munnes,M., Doerfler,W., Goossens,M., Munnich,A., Vekemans,M. and Lyonnet,S. (2000) Neurological phenotype in Waardenburg syndrome type 4 correlates with novel SOX10 truncating mutations and expression in developing brain. Am. J. Hum. Genet., 66, 1496-1503.
22. Werner,M.H. and Burley,S.K. (1997) Architectural transcription factors: proteins that remodel DNA. Cell, 88, 733-736.
23. Privalov,P.L., Jelesarov,I., Read,C.M., Dragan,A.I. and Crane-Robinson,C. (1999) The energetics of HMG box interactions with DNA: thermodynamics of the DNA binding of the HMG box from mouse sox-5. J. Mol. Biol., 294, 997-1013.
24. Scaffidi,P. and Bianchi,M.E. (2001) Spatially precise DNA bending is an essential activity of the sox2 transcription factor. J. Biol. Chem., 276, 47296-47302.