Linkage disequilibrium between dopamine D1 receptor gene (DRD1) and bipolar disorder

Biological Psychiatry

Volumn 52, Issue 12, 2002, Pages 1144-1150

  Ni, Xingqun ^a   Trakalo, Joseph M ^a   Mundo, Emanuela ^b   Macciardi, Fabio M ^b   Parikh, Sagar ^b   Lee, Lisa ^a   Kennedy, James L ^b  

^a CENTRE FOR ADDICTION AND MENTAL HEALTH   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

Bipolar disorder; Dopamine D1 receptor gene; Genetics; Haplotype transmission disequilibrium test; Linkage; Transmission disequilibrium test

Indexed keywords

DOPAMINE 1 RECEPTOR;

ALLELE; ARTICLE; BIPOLAR I DISORDER; BIPOLAR II DISORDER; CALCULATION; CONTROLLED STUDY; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOTYPE; HAPLOTYPE; HUMAN; MAJOR CLINICAL STUDY; PRIORITY JOURNAL;

ADULT; ALLELES; ANALYSIS OF VARIANCE; BIPOLAR DISORDER; DNA PRIMERS; FEMALE; GENE FREQUENCY; GENOTYPE; HUMANS; LINKAGE DISEQUILIBRIUM; MALE; POLYMORPHISM, GENETIC; RECEPTORS, DOPAMINE D1;

EID: 0037115051     PISSN: 00063223     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3223(02)01433-6     Document Type: Article

References (46)

1. Diagnostic and Statistical Manual of Mental Disorders. 4th ed:1994;American Psychiatric Press, Washington, DC.
2. Bellivier F., Golmard J.-L., Henry C., Leboyer M., Schurhoff F. Admixture analysis of age at onset in bipolar I affective disorder. Arch Gen Psychiatry. 58:2001;510-512.
3. Blackwood D., Muir W. Molecular genetics and the epidemiology of bipolar disorder. Ann Med. 33:2001;242-247.
4. Cichon S., Nothen M.M., Erdmann J., Propping P. Detection of four polymorphic sites in the human dopamine D1 receptor gene (DRD1). Hum Mol Genet. 209:1994;3.
5. Cichon S., Nothen M.M., Rietschel M., Korner J., Propping P. Single-strand conformation analysis (SSCA) of the dopamine D1 receptor gene (DRD1) reveals no significant mutation in patients with schizophrenia and manic depression. Biol Psychiatry. 36:1994;850-853.
6. Cichon S., Nothen M.M., Stober G., Schroers R., Albus M., Maier W., et al. Systematic screening for mutations in the 5′-regulatory region of the human dopamine D1 receptor (DRD1) gene in patients with schizophrenia and bipolar affective disorder. Am J Med Genet. 67:1996;424-428.
7. Civelli O., Bunzow J.R., Grandy D.C., Zhou Q.-Y., van Tol H.H.M. Molecular biology of the dopamine receptors. Eur J Pharmacol. 207:1991;277-286.
8. Clayton D. A generalization of the transmission/disequilibrium test for uncertain-haplotype transmission. Am J Hum Genet. 65:1999;1170-1177.
9. Clayton D., Johns H.B. Transmission/disequilibrium test for extended marker haplotypes. Am J Hum Genet. 65:1999;1161-1169.
10. Coon H., Jensen S., Hoff M., Holik J., Plaetke R., Reimherr F., et al. A genome-wide search for genes predisposing to manic-depression, assuming autosomal dominant inheritance. Am J Hum Genet. 56:1993;1234-1249.
11. Crowe R.R., Vieland V. Report of the Chromosome 5 Workshop of the Sixth World Congress on Psychiatric Genetics. Am J Med Genet. 88:1999;229-232.
12. Dearry A., Gingrich J.A., Falardeau P., Fremeau R.T., Bates M.D., Caron M.G. Molecular cloning and expression of the gene for a human D1 dopamine receptor. Nature. 347:1990;72-75.
13. Edenberg H.J., Foroud T., Conneally P.M., Sorbel J.J., Carr K., Crose C., et al. Initial genomic scan of the NIMH genetics initiative bipolar pedigrees Chromosomes 3, 5, 15, 16, 17, and 22 . Am J Med Genet. 74:1997;238-246.
14. Fallin D., Cohen A., Essioux L., Chumakov I., Blumenfeld M., Cohen D., Schork N.J. Genetic analysis of case/control data using estimated haplotype frequencies Application to APOE locus variation and Alzheimer's disease . Genome Res. 11:2001;143-151.
15. First M.B., Spitzer R.L., Williams J.B.W., Gibbon M. Structured Clinical Interview for DSM-IV (SCID-I) (User's Guide and Interview) Research Version. 1995;Biometrics Research Department, New York State Psychiatric Institute, New York.
16. Garner C., McInnes L.A., Service S.K., Spesny M., Fournier E., Leon P., Freimer N.B. Linkage analysis of a complex pedigree with severe bipolar disorder, using a Markov chain Monte Carlo method. Am J Hum Genet. 68:2001;1061-1064.
17. Goodwin F.K., Jamison K.R. Manic-Depression Illness. 1990;Oxford University Press, Oxford, UK.
18. Gottberg E., Montreuil B., Reader T.A. Acute effects of lithium on dopaminergic responses Iontophoretic studies in the rat visual cortex . Synapse. 2:1988;442-449.
19. Grandy D.K., Zhou Q.Y., Allen L., Litt R., Magenis R.E., Civelli O., Litt M. A human D1 dopamine receptor gene is located on chromosome 5 at q35.1 and identifies an EcoRI RFLP. Am J Hum Genet. 47:1990;828-834.
20. Hong K.S., McInnes L.A., Service S.K., Song T., Lucas J., Silva S., et al. Genetic mapping using haplotype and model-free linkage analysis supports previous evidence for a locus predisposing to severe bipolar disorder at 5q31-q33. Am J Hum Genet. 69:(suppl):2001;534.
21. Jensen S., Plaetke R., Holik J., Hoff M., O'Connell P., Reimherr F., et al. Linkage analysis of the D1 dopamine receptor gene and manic depression in six families. Hum Hered. 42:1992;269-275.
22. Knapp M. A note on power approximation for the transmission/disequilibrium test. Am J Hum Genet. 64:1999;1177-1185.
23. Kornberg J.R., Brown J.L., Sadovnick A.D., Remick R.A., Keck P.E. Jr, McElroy S.L., et al. Evaluating the parent-of-origin effect in bipolar affective disorder: Is a more penetrant subtype transmitted paternally? J Affect Disord. 59:2000;183-192.
24. Lahiri D.K., Nurnberger J.I. A rapid no-enzymatic method for the preparation of HMW DNA from blood for RFLP analysis. Nucl Acids Res. 19:1991;5444.
25. Martin E.R., Lai E.H., Gilbert J.R., Rogala A.R., Afshari A.J., Riley J., et al. SNPing away at complex diseases Analysis of single-nucleotide polymorphisms around APOE in Alzheimer disease . Am J Hum Genet. 67:2000;383-394.
26. McGinnis R. General equations for Pt, Ps, and the power of the TDT and the affected-sib-pair test. Am J Hum Genet. 67:2000;1340-1347.
27. McMahon F.J., Stine O.C., Meyers D.A., Simpson S.G., DePaulo J.R. Patterns of maternal transmission in bipolar affective disorder. Am J Hum Genet. 56:1995;1277-1286.
28. Minowa M.T., Minowa T., Monsma F.J., Sibley D.R., Mouradian M.M. Characterization off the 5′ flanking region of the human D1A dopamine receptor gene. Proc Natl Acad Sci U S A. 89:1992;3045-3049.
29. Mitchell P., Selbie L., Waters B., Donald J., Vivero C., Tully M., Shine J. Exclusion of close linkage of bipolar disorder to dopamine D1 and D2 receptor gene markers. J Affect Disord. 25:1992;1-12.
30. Mundo E., Walker M., Cate T., Macciardi F., Kennedy J.L. The role of serotonin transporter protein gene in antidepressant-induced mania in bipolar disorder Preliminary findings . Arch Gen Psychiatry. 58:2001;539-544.
31. Mundo E., Walker M., Tims H., Macciardi F., Kennedy J.L. Lack of linkage disequilibrium between serotonin transporter protein gene (SLC6A4) and bipolar disorder. Am J Med Genet. 96:2000;379-383.
32. Mundo E., Zai G., Lee L., Parikh S.V., Kennedy J.L. The 5HT1 Dbeta receptor gene in bipolar disorder A family-based association study . Neuropsychopharmacology. 25:2001;608-613.
33. Savoye C., Laurent C., Amadeo S., Gheysen F., Leboyer M., Lejeune J., et al. No association between dopamine D1, D2, and D3 receptor genes and manic-depressive illness. Biol Psychiatry. 44:1998;644-647.
34. Schurhoff F., Bellivier F., Jouvent R., Mouren-Simeoni M.C., Bouvard M., Allilaire J.F., Leboyer M. Early and late onset bipolar disorders Two different forms of manic-depressive illness? J Affect Disord. 58:2000;215-221.
35. Shah M., Coon H., Holik J., Hoff M., Helmer V., Panos P. Mutation scan of the D1 dopamine receptor gene in 22 cases of bipolar I disorder. Am J Med Genet. 60:1995;150-153.
36. Sham P.C., Curtis D. An extended transmission/disequilibrium test (TDT) for multi-allele marker loci . Ann Hum Genet. 59:1995;323-336.
37. Silverstone T., Romans-Clarkson G. Bipolar affective disorder Causes and prevention of relapse . Br J Psychiatry. 154:1989;321-335.
38. Spielman R.S., Ewens W.J. A sibship test for linkage in the presence of association The sib transmission/disequilibrium test . Am J Hum Genet. 62:1998;450-458.
39. Spielman R.S., McGinnis R.E., Ewens W.J. Transmission test for linkage disequilibrium The insulin gene region and insulin-dependent diabetes mellitus (IDDM) . Am J Hum Genet. 52:1993;506-516.
40. Stine O.C., Xu J., Koskela R., McMahon F.J., Gschwend M., Friddle C., et al. Evidence for linkage of bipolar disorder to chromosome 18 with a parent-of-origin effect. Am J Hum Genet. 57:1995;1384-1394.
41. Suhara T., Nakayama K., Inoue O., Fukuda H., Shimizu M., Mori A., Tateno Y. D1 dopamine receptor binding in mood disorders measured by positron emission tomography. Psychopharmacology. 106:1992;14-18.
42. Sunahara R.K., Niznik H.B., Weiner D.M., Stormann T.M., Brann M.R., Kenndy J.L., et al. Human dopamine D1 receptor encoded by an intronless gene on chromosome 5. Nature. 347:1990;80-83.
43. Suppes T., McElroy S.L., Gilbert J., Dessain E.C., Cole J.O. Clozapine in the treatment of dysphoric mania. Biol Psychiatry. 32:1992;270-280.
44. Winokur G., Reich T. Two genetic factors in manic-depressive disease. Compr Psychiatry. 11:1970;93-99.
45. Zhou Q.Y., Grandy D.K., Thambi L., Kushner J.A., Van Tol H.H.M., Cone R., et al. Cloning and expression of human and rat D1 dopamine receptors. Nature. 347:1990;76-79.
46. Zollner S., van Haeseler A. A coalescent approach to study linkage disequilibrium between single-nucleotide polymorphisms. Am J Hum Genet. 66:2000;615-628.