UVR-induced oxidative stress in human skin in vivo: Effects of oral vitamin C supplementation

Free Radical Biology and Medicine

Volumn 33, Issue 10, 2002, Pages 1355-1362

  McArdle, F ^a   Rhodes, L E ^a   Parslew, R ^a   Jack, C I A ^a   Friedmann, P S ^a   Jackson, M J ^a  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

Author keywords

Antioxidants; Ascorbic acid; Free radicals; Reactive oxygen species; Transcription factors

Indexed keywords

ANTIOXIDANT; ASCORBIC ACID; CATALASE; GLUTATHIONE; MALONALDEHYDE; THIOL DERIVATIVE; TRANSCRIPTION FACTOR AP 1; ALPHA TOCOPHEROL; DNA; FATTY ACID; FREE RADICAL; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR;

ADULT; ARTICLE; BIOAVAILABILITY; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; OXIDATION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DNA BINDING; RADIATION EXPOSURE; RADIATION INJURY; SKIN; SKIN CELL; SKIN INJURY; TISSUE LEVEL; ULTRAVIOLET B RADIATION; ULTRAVIOLET RADIATION; VITAMIN BLOOD LEVEL; VITAMIN SUPPLEMENTATION; VOLUNTEER; BIOPSY; DIET SUPPLEMENTATION; ERYTHEMA; METABOLISM; PROTEIN BINDING; TIME;

MURINAE;

ADULT; ASCORBIC ACID; BIOPSY; CATALASE; DIETARY SUPPLEMENTS; DNA; ERYTHEMA; FATTY ACIDS; FEMALE; FREE RADICALS; GLUTATHIONE; HUMANS; MALE; MALONDIALDEHYDE; OXIDATIVE STRESS; PROTEIN BINDING; REACTIVE OXYGEN SPECIES; SKIN; SULFHYDRYL COMPOUNDS; TIME FACTORS; TRANSCRIPTION FACTOR AP-1; TRANSCRIPTION FACTORS; ULTRAVIOLET RAYS; VITAMIN E;

EID: 0037111370     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(02)01042-0     Document Type: Article

References (40)

1. Pathak M.A., Fitzpatrick T.B. Preventive treatment of sunburn, dermatoheliosis, and skin cancer with sun-protective agents. Fitzpatrick T.B., Eisen A.Z., Wolff K., Freedburg I.M., Austen K.F., Dermatology in general medicine. 4th ed:1993;1689-1716 McGraw-Hill, Inc, New York.
2. Miyachi Y. Reactive oxygen species in photodermatology. Hayashi O., Imamura S., Miyachi Y., The biological role of reactive oxygen species in skin. 1987;37-41 Elsevier Science, New York.
3. Kligman L.H., Kligman A.M. The nature of photoaging its prevention and repair . Photodermatology. 3:1986;215-227.
4. Frederick J.E. Ultraviolet sunlight reaching the earth's surface a review of recent research . Photochem. Photobiol. 57:1993;175-178.
5. Black H.S. Potential involvement of free radical reactions in ultraviolet light-mediated cutaneous damage. Photochem. Photobiol. 46:1987;213-221.
6. Tyrrell R.M. Ultraviolet radiation and free radical damage to skin. Biochem. Soc. Trans. 61:1996;47-53.
7. Meewes C., Brenneisen P., Wenk J., Kuhr L., Ma W., Alikoski J., Poswig A., Krieg T., Schaffetter-Kochanek K. Adaptive antioxidant response protects dermal fibroblasts from UVA-induced phototoxicity. Free Radic. Biol. Med. 30:2001;238-247.
8. Soriani M., Hejmadi V., Tyrrell R.M. Modulation of c-jun and c-fos transcription by UVB and UVA radiations in human dermal fibroblasts and KB cells. Photochem. Photobiol. 71:2000;551-558.
9. Moysan A., Marquis I., Gaboriau F., Santus R., Dubertret L., Morliere P. Ultraviolet A-induced lipid peroxidation and antioxidant defense systems in cultured human skin fibroblasts. J. Invest. Dermatol. 100:1993;692-698.
10. Shindo Y., Witt E., Han D., Packer L. Dose-response effects of acute ultraviolet irradiation on antioxidants and molecular markers of oxidation in murine epidermis and dermis. J. Invest. Dermatol. 102:1994;470-475.
11. Lopez-Torres M., Thiele J.J., Shindo Y., Han D., Packer L. Topical application of α-tocopherol modulates the antioxidant network and diminishes ultraviolet-induced oxidative damage in murine skin. Br. J. Dermatol. 138:1998;207-215.
12. Connor M.J., Wheeler L.A. Depletion of cutaneous glutathione by ultraviolet radiation. Photochem. Photobiol. 46:1987;239-245.
13. Gonzalez S., Pathak M.A. Inhibition of ultraviolet-induced formation of reactive oxygen species, lipid peroxidation, erythema and skin photosensitization by Polypodium leucotomos. Photodermatol. Photoimmunol. Photomed. 12:1996;45-56.
14. Tyrell R.M., Pidoux M. Correlation between endogenous glutathione content and the sensitivity of cultured human skin cells to radiation at defined wavelengths in the solar UV range. Photochem. Photobiol. 47:1988;405-412.
15. Jones S.A., McArdle F., Jack C.I.A., Jackson M.J. Effect of antioxidant supplementation on the adaptive response of human skin fibroblasts to UV-induced oxidative stress. Redox Rep. 4:1999;291-299.
16. Schallreuter K.A., Wood J.M. Thioredoxin reductase - its role in epidermal redox status. J. Photochem. Photobiol. B. 64:2001;179-184.
17. Katiyar S.K., Afaq F., Pewrez A., Mukhtar H. Green tea polyphenol (-)-epigallocatechin-3-gallate treatment of human skin inhibits ultraviolet radiation-induced oxidative stress. Carcinogenesis. 22:2001;287-294.
18. Tyrell R.M. Activation of mammalian genes by the UV component of sunlight - from models to reality. Bioessays. 18:1996;139-148.
19. Nachbar F., Korting H.C. The role of vitamin E in normal and damaged skin. J. Mol. Med. 73:1995;7-17.
20. Fuchs J., Kern H. Modulation of UV-light induced skin inflammation by d-alpha-tocopherol and l-ascorbic acid a clinical study using solar-simulated radiation . Free Radic. Biol. Med. 25:1998;1006-1012.
21. Stewart M.S., Cameron G.S., Pence B.C. Antioxidant nutrients protect against UVB-induced oxidative damage to DNA of mouse keratinocytes in culture. J. Invest. Dermatol. 106:1996;1976-1989.
22. Tebbe B., Wu S., Geilen C.C., Eberle J., Kodelija V., Orfanos C.E. L-ascorbic acid inhibits UVA-induced lipid peroxidation and secretion of IL-1α and IL-6 in cultured human keratinocytes in vitro. J. Invest. Dermatol. 108:1997;302-306.
23. Dunham W.B., Zuckerkandl E., Reynolds R., Willoughby R., Marcuson R., Barth R., Pauling L. Effects of intake of L-ascorbic acid (vitamin C) on the incidence of dermal neoplasms induced in mice by ultraviolet light. Proc. Natl. Acad. Sci. USA. 79:1982;7532-7536.
24. Claiborne A. Catalase activity. Greenwald R.A., CRC handbook of methods for oxygen radical research. 1985;283-284 CRC Press, Boca Raton, FL.
25. Fukunaga K., Suzuki T., Takama K. Highly sensitive high-performance liquid chromatography for the measurement of malondialdehyde in biological samples. J. Chromatogr. 621:1993;77-81.
26. Anderson M.E. Measurement of antioxidants glutathione . Punchard N.A., Kelly F.J., Free radicals, a practical approach. 1996;213-226 IRL Press, Oxford.
27. 2+ homeostasis. Arch. Biochem. Biophys. 235:1984;343-350.
28. Smith P.K., Krohn R.I., Hermanson G.T., Mallia A.K., Gartner F.H., Provenzano M.D., Fujimoto E.K., Goeke N.M., Olson B.J., Klenk D.C. Measurement of protein using bicinchoninic acid. Anal. Biochem. 150:1985;76-85.
29. Folch J., Lees M., Stanley G.S.H. A simple method for the isolation and purification of total lipids from animal tissues. J. Biol. Chem. 226:1957;497-503.
30. Metcalf L.D., Schmitz A.A. Boron-trifluoride method for the derivitisation of fatty acids. Anal. Chem. 33:1961;363-370.
31. Mohr D., Stocker R. Selective and sensitive measurement of vitamin C, ubiquinol-10, and other low molecular weight antioxidants. Punchard N.A., Kelly F.J., Free radicals, a practical approach. 1996;271-285 IRL Press, Oxford.
32. Catignani G.L., Bieri J.G. Rat liver alpha-tocopherol binding protein. Biochim. Biophys. Acta. 497:1983;349-357.
33. Shindo Y., Packer L. Antioxidant defense mechanisms in murine epidermis and dermis and their responses to ultraviolet light. J. Invest. Dermatol. 100:1993;260-265.
34. Reimer D., Bailley J., Singh S. Complete cDNA and 5′genomic sequence and multilevel regulation of the mouse catalase gene. Genomics. 15:1994;325-336.
35. Halliwell B., Gutteridge J.M.C. Free radicals in biology and medicine. 1989;Oxford University Press, Oxford, UK.
36. Rhodes L.E., O'Farrell S., Jackson M.J., Friedmann P.S. Dietary omega-3 fatty acids reduce UVB-induced erythema while increasing lipid peroxidation. J. Invest. Dermatol. 103:1994;151-154.
37. Jackson M.J., McArdle A., McArdle F. Antioxidant micronutrients and gene expression. Proc. Nutr. Soc. 57:1988;301-305.
38. Packer J.E., Slater T., Wilson R.L. Direct observation of a free radical interaction between vitamin E and vitamin C. Nature. 278:1979;737-738.
39. Fuchs J. Potentials and limitations of the natural antioxidants RRR-alpha-tocopherol, L-ascorbic acid and b-carotene in cutaneous photoprotection. Free Radic. Biol. Med. 25:1998;848-873.
40. Eberlin-Konig B., Placzek M., Przybilla B. Protective effect against sunburn of combined systemic ascorbic acid (vitamin C) and d-α-tocopherol (vitamin E). J. Am. Acad. Dermatol. 38:1998;45-48.