Expression of somatostatin receptor subtypes 2 and 4 in human benign prostatic hyperplasia and prostatic cancer

Prostate

Volumn 53, Issue 1, 2002, Pages 50-59

  Hansson, Jens ^a   Bjartell, Anders ^a   Gadaleanu, Virgil ^a   Dizeyi, Nishtman ^a   Abrahamsson, Per Anders ^a  

^a LUND UNIVERSITY   (Sweden)

Author keywords

Growth substances; In situ hybridization; Neurosecretory systems pathology; Prostatic cancer; Receptors, somatostatin

Indexed keywords

FLUORESCEIN; GROWTH PROMOTOR; MESSENGER RNA; RECEPTOR SUBTYPE; SOMATOSTATIN; SOMATOSTATIN RECEPTOR;

ADULT; AGED; ARTICLE; CANCER CELL; CONTROLLED STUDY; HUMAN; HUMAN TISSUE; IN SITU HYBRIDIZATION; MALE; NEUROSECRETION; NUCLEOTIDE SEQUENCE; PATHOLOGY; PRIORITY JOURNAL; PROSTATE CANCER; PROSTATE EPITHELIUM; PROSTATE HYPERTROPHY; PROTEIN EXPRESSION; STROMA CELL; TISSUE DISTRIBUTION;

CARCINOMA; DNA PRIMERS; GENE EXPRESSION REGULATION; HUMANS; IN SITU HYBRIDIZATION; MALE; MEMBRANE PROTEINS; PROSTATIC HYPERPLASIA; PROSTATIC NEOPLASMS; RECEPTORS, SOMATOSTATIN; RNA, MESSENGER; UP-REGULATION;

EID: 0037106043     PISSN: 02704137     EISSN: None     Source Type: Journal    
DOI: 10.1002/pros.10121     Document Type: Article

References (52)

1. Hormones and carcinogenesis
2. Normal human mammary epithelial cells spontaneously escape senescence and acquire genomic changes
3. Neuroendocrine cells in tumour growth of the prostate
4. Inability of complete androgen blockade to increase survival of patients with advanced prostatic cancer as compared to standard hormonal therapy
5. Activation of the androgen receptor by polypeptide growth factors and cellular regulators
6. Androgens, androgen receptors, antiandrogens and the treatment of prostate cancer
7. Neuroendocrine differentiation in prostatic carcinoma: An update
8. Androgen-independent growth is induced by neuropeptides in human prostate cancer cell lines
9. Somatostatin and/or somatostatin-like immunoreactive endocrine-paracrine cells in the human prostate gland
10. Somatostatin and its receptor family
11. Direct inhibitory effect of somatostatin on the growth of the human prostatic cancer cell line LNCaP: Possible mechanism of action
12. Somatostatin analog RC-160 and bombesin/gastrin-releasing peptide antagonist RC-3095 inhibit the growth of androgen-independent DU-145 human prostate cancer line in nude mice
13. Targeted cytotoxic analogue of somatostatin AN-238 inhibits growth of androgen-independent Dunning R-3327-AT-1 prostate cancer in rats at nontoxic doses
14. High expression of somatostatin receptors and messenger ribonucleic acid for its receptor subtypes in organ-confined and locally advanced human prostate cancers
15. Development of selective antibodies against the human somatostatin receptor subtypes sst1-sst5
16. Localization and mRNA expression of somatostatin receptor subtypes in human prostatic tissue and prostate cancer cell lines
17. Somatostatin receptors in human prostate and prostate cancer
18. [111In-DTPA-D-Phe1]-octreotide scintigraphy in patients with hormone-refractory prostatic adenocarcinoma can predict therapy outcome with octreotide treatment: A pilot study
19. Metastatic hormone-refractory prostatic adenocarcinoma expresses somatostatin receptors and is visualized in vivo by [111In]-labeled DTPA-D-[Phe1]-octreotide scintigraphy
20. Expression of somatostatin receptors in human prostatic cell lines
21. Different expression patterns of somatostatin receptor subtypes in cultured epithelial cells from human normal prostate and prostate cancer
22. Cloning and functional characterization of a family of human and mouse somatostatin receptors expressed in brain, gastrointestinal tract, and kidney
23. Cloning and characterization of a fourth human somatostatin receptor
24. Differential expression of five somatostatin receptor subtypes, SSTR1-5, in the CNS and peripheral tissue
25. Synthesis of cRNA probes from PCRgenerated DNA
26. Somatostatin receptors, an expanding gene family: Cloning and functional characterization of human SSTR3, a protein coupled to adenylyl cyclase
27. Cloning, functional expression and pharmacological characterization of a fourth (hSSTR4) and a fifth (hSSTR5) human somatostatin receptor subtype
28. Differential expression of peroxisome proliferator-activated receptors (PPARs): Tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat
29. Somatostatin receptor subtypes sst1, sst2, sst3, and sst5 expression in human pituitary, gastroentero-pancreatic and mammary tumors: Comparison of mRNA analysis with receptor autoradiography
30. Somatostatin receptors present knowledge and future directions
31. Receptors for dopamine and somatostatin: Formation of hetero-oligomers with enhanced functional activity
32. Subtypes of the somatostatin receptor assemble as functional homo- and heterodimers
33. Phase I-II study of the somatostatin analogue lanreotide in hormone-refractory prostate cancer
34. Cyclin E as a coactivator of the androgen receptor
35. sst2 somatostatin receptor mediates cell cycle arrest and induction of p27(Kip1). Evidence for the role of SHP-1
36. Somatostatin interferes with thyrotropin-induced G1-S transition mediated by cAMP-dependent protein kinase and phosphatidylinositol 3-kinase. Involvement of RhoA and cyclin E x cyclin-dependent kinase 2 complexes
37. Somatostatin inhibits Akt phosphorylation and cell cycle entry, but not p42/p44 mitogen-activated protein (MAP) kinase activation in normal and tumoral pancreatic acinar cells
38. Androgen receptor signalling in the prostate
39. Androgen receptor activation in prostatic tumor cell lines by insulin-like growth factor-I, keratinocyte growth factor, and epidermal growth factor
40. Characterization of the role of IL-6 in the progression of prostate cancer
41. Modulation of cytokine production in activated human monocytes by somatostatin
42. Insulin-like growth factor-I is an autocrine regulator of chromogranin A secretion and growth in human neuroendocrine tumor cells
43. The effect of somatostatin analogue SMS 201-995 on serotonin levels in the medium of primary carcinoid cell cultures
44. Somatostatin inhibits the secretion of bombesin-like peptides from small cell lung cancer cells
45. Caspase-8-mediated intracellular acidification precedes mitochondrial dysfunction in somatostatin-induced apoptosis
46. Effect of somatostatin and octreotide on proliferation and vascular endothelial growth factor secretion from murine endothelial cell line (HECa10) culture
47. Association between immunohistochemical expression of vascular endothelial growth factor (VEGF), VEGF-expressing neuroendocrine-differentiated tumor cells, and outcome in prostate cancer patients subjected to watchful waiting
48. Insulin-like growth factor I stimulates angiogenesis and the production of vascular endothelial growth factor
49. Rapid identification of subtype-selective agonists of the somatostatin receptor through combinatorial chemistry
50. New somatostatin analogues for radiotherapy of somatostatin receptor expressing tumours
51. Growth inhibition of human prostatic carcinoma cell lines by serotonin antagonists