Mutations in the runt homology domain of CBFα2 in myeloid malignancies with acquired trisomy 21 [2]

Cancer Genetics and Cytogenetics

Volumn 136, Issue 2, 2002, Pages 151-152

  Snaddon, Jennifer ^a   Neat, Michael ^a   Fitzgibbon, Jude ^a   Smith, Matthew L ^a   Rohatiner, Ama Z ^a   Lister, T Andrew ^a   Amess, John A ^a  

^a ST BARTHOLOMEW S HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CORE BINDING FACTOR; DNA; TRANSCRIPTION FACTOR RUNX; UNCLASSIFIED DRUG;

ACUTE GRANULOCYTIC LEUKEMIA; ANALYTIC METHOD; BLAST CELL; BLOOD CELL; BONE MARROW CELL; CANCER CLASSIFICATION; CELL COUNT; CHROMOSOME TRANSLOCATION; CLINICAL ARTICLE; CLONE; CONTROLLED STUDY; CRYOPRESERVATION; CYTOGENETICS; DNA EXTRACTION; DNA SEQUENCE; FEMALE; GENE MUTATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; KARYOTYPE; LETTER; MALE; MUTATIONAL ANALYSIS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; SEQUENCE HOMOLOGY; TRISOMY 21;

AGED; DOWN SYNDROME; FEMALE; HUMANS; MUTATION; NEOPLASM PROTEINS; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; TRANSCRIPTION FACTORS;

EID: 0037101568     PISSN: 01654608     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-4608(02)00525-3     Document Type: Letter

References (6)

1. Osato M., Asou N., Abdalla E., Hoshino K., Yamasaki H., Okubo T., Suzushima H., Takatsuki K., Kanno T., Shigesada K., Ito Y. Biallelic and heterozygous point mutations in the runt domain of the AML1/PEBP2alphaB gene associated with myeloblastic leukemia. Blood. 93:1999;1817-1824.
2. Preudhomme C., Warot-Loze D., Roumier C., Grardel-Duflos N., Garand R., Lai J.L., Dastugue N., Macintyre E., Denis C., Bauters F., Kerckaert J.P., Cosson A., Fenaux P. High incidence of biallelic point mutations in the Runt domain of the AML1/PEBP2 alpha B gene in M0 acute myeloid leukemia and in myeloid malignancies with acquired trisomy 21. Blood. 96:2000;2862-2869.
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