Changes in rat frontal cortex gene expression following chronic cocaine

Molecular Brain Research

Volumn 104, Issue 1-2, 2002, Pages 11-20

  Freeman, Willard M ^a,b   Brebner, Karen ^a   Lynch, Wendy J ^a   Patel, Kruti M ^a   Robertson, Daniel J ^a   Roberts, David C S ^a   Vrana, Kent E ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

Activity regulated cytoskeletal protein; Gene expression; Mesocortical; Microarray; Nerve growth factor I B (NGFI B); Protein tyrosine kinase 2

Indexed keywords

COCAINE; COMPLEMENTARY DNA; CYTOSKELETON PROTEIN; MESSENGER RNA; NERVE GROWTH FACTOR; PROTEIN TYROSINE KINASE; ACTIVITY REGULATED CYTOSKELETAL ASSOCIATED PROTEIN; ACTIVITY REGULATED CYTOSKELETAL-ASSOCIATED PROTEIN; CELL RECEPTOR; DNA BINDING PROTEIN; DOPAMINE UPTAKE INHIBITOR; FOCAL ADHESION KINASE 2; NERVE PROTEIN; NUCLEAR RECEPTOR NUR77; PTK2B PROTEIN, RAT; STEROID RECEPTOR; TRANSCRIPTION FACTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA HYBRIDIZATION; DNA MICROARRAY; ENZYME SUBUNIT; FRONTAL CORTEX; GENE EXPRESSION; IMMUNOBLOTTING; IMMUNOREACTIVITY; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN INDUCTION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCREENING; ANIMAL; COCAINE DEPENDENCE; DRUG ADMINISTRATION; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; IN SITU HYBRIDIZATION; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; PREFRONTAL CORTEX; SPRAGUE DAWLEY RAT; UPREGULATION;

ANIMAL; COCAINE; COCAINE-RELATED DISORDERS; CYTOSKELETAL PROTEINS; DNA-BINDING PROTEINS; DOPAMINE UPTAKE INHIBITORS; DRUG ADMINISTRATION SCHEDULE; GENE EXPRESSION REGULATION; IMMUNOBLOTTING; IN SITU HYBRIDIZATION; MALE; NERVE TISSUE PROTEINS; PREFRONTAL CORTEX; PROTEIN-TYROSINE KINASE; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; SUPPORT, U.S. GOV'T, P.H.S.; TRANSCRIPTION FACTORS; UP-REGULATION; ANIMALS; FOCAL ADHESION KINASE 2; PROTEIN-TYROSINE KINASES; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, STEROID;

ANIMALIA;

EID: 0037099242     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-328X(02)00197-3     Document Type: Article

References (48)

1. Effects of chronic exposure to cocaine are regulated by the neuronal protein Cdk5
2. Hippocampal afferents to the rat prefrontal cortex: Synaptic targets and relation to dopamine terminals
3. Projections from the rat prefrontal cortex to the ventral tegmental area: Target specificity in the synaptic associations with mesoaccumbens and mesocortical neurons
4. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
5. Differential regulation of FAK+ and PYK2/Cakbeta, two related tyrosine kinases, in rat hippocampal slices: Effects of LPA, carbachol, depolarization and hyperosmolarity
6. Activation of arc, a putative 'effector' immediate early gene, by cocaine in rat brain
7. Cocaine-responsive gene expression changes in rat hippocampus
8. Chronic cocaine-mediated changes in non-human primate nucleus accumbens gene expression
9. Fundamentals of DNA hybridization arrays for gene expression analysis
10. Quantitative RT-PCR: Pitfalls and potential
11. Neuroadaptations in ionotropic and metabotropic glutamate receptor mRNA produced by cocaine treatment
12. FAK and PYK2/CAKbeta in the nervous system: A link between neuronal activity, plasticity and survival
13. Inhibition of activity-dependent arc protein expression in the rat hippocampus impairs the maintenance of long-term potentiation and the consolidation of long-term memory
14. Environment-specific expression of the immediate-early gene Arc in hippocampal neuronal ensembles
15. CAKbeta/Pyk2 kinase is a signaling link for induction of long-term potentiation in CA1 hippocampus
16. Pyk2 and FAK regulate neurite outgrowth induced by growth factors and integrins
17. Acquisition of a novel behavior induces higher levels of Arc mRNA than does overtrained performance
18. Expression of the transcription factor deltaFosB in the brain controls sensitivity to cocaine
19. A robust increase in expression of arc gene, an effector immediate early gene, in the rat brain after acute and chronic methamphetamine administration
20. Expression of c-fos, NGFI-A and secretogranin II mRNA in brain regions during initiation of cocaine self-administration in mice
21. Protein tyrosine kinase PYK2 involved in Ca(2+)-induced regulation of ion channel and MAP kinase functions
22. Both glutamate receptor antagonists and prefrontal cortex lesions prevent induction of cocaine sensitization and associated neuroadaptations
23. The expression of cocaine sensitization is not prevented by MK-801 or ibotenic acid lesions of the medial prefrontal cortex
24. The NGFI-B subfamily of the nuclear receptor superfamily
25. DNA-binding mechanism of the monomeric orphan nuclear receptor NGFI-B
26. Molecular basis of long-term plasticity underlying addiction
27. Use of image analysis to quantitate changes in form of mitochondrial DNA after x-irradiation
28. Ventral tegmental (A10) system: Neurobiology. 1. Anatomy and connectivity
29. A new mathematical model for relative quantification in real-time RT- PCR
30. Ibotenic acid lesions of the dorsal prefrontal cortex disrupt the expression of behavioral sensitization to cocaine
31. The organization of projections from the mediodorsal nucleus of the thalamus to orbital and medial prefrontal cortex in macaque monkeys
32. On the role of ascending catecholaminergic systems in intravenous self-administration of cocaine
33. Incentive-sensitization and addiction
34. Cocaine self-administration alters the morphology of dendrites and dendritic spines in the nucleus accumbens and neocortex
35. Alterations in the morphology of dendrites and dendritic spines in the nucleus accumbens and prefrontal cortex following repeated treatment with amphetamine or cocaine
36. Gamma-hydroxybutyrate and cocaine administration increases mRNA expression of dopamine D1 and D2 receptors in rat brain
37. 'Binge' cocaine administration induces a sustained increase of prodynorphin mRNA in rat caudate-putamen
38. The effects of acute and repeated cocaine injections on protein kinase C activity and isoform levels in dopaminergic brain regions
39. Synaptic activation causes the mRNA for the IEG Arc to localize selectively near activated postsynaptic sites on dendrites
40. A cellular mechanism for targeting newly synthesized mRNAs to synaptic sites on dendrites
41. Selective targeting of newly synthesized Arc mRNA to active synapses requires NMDA receptor activation
42. The activity-regulated cytoskeletal-associated protein arc is expressed in different striosome-matrix patterns following exposure to amphetamine and cocaine
43. Addiction, a disease of compulsion and drive: Involvement of the orbitofrontal cortex
44. Differential intracellular sorting of immediate early gene mRNAs depends on signals in the mRNA sequence
45. NGFI-B and Nor1 mRNAs are upregulated in brain reward pathways by drugs of abuse: Different effects in Fischer and Lewis rats
46. Differential patterns of induction of NGFI-B, Nor1 and c-fos mRNAs in striatal subregions by haloperidol and clozapine
47. Acute 'binge' cocaine increases mu-opioid receptor mRNA levels in areas of the rat mesolimbic mesocortical dopamine system