Multiple PU.1 sites cooperate in the regulation of p40phox transcription during granulocytic differentiation of myeloid cells

Blood

Volumn 99, Issue 12, 2002, Pages 4578-4587

  Li, Sen N ^a,b,c   Valante, Anthony J ^a,b,c   Qiang, Mei ^a,b,c   Schlegel, Werner ^a,b,c   Gamez, Maria ^a,b,c   Clark, Robert A ^a,b,c,d  

^a Mays Cancer Center at UT Health San Antonio   (United States)

^b SOUTH TEXAS VETERANS HEALTH CARE SYSTEM   (United States)

^c UNIVERSITY OF GENEVA   (Switzerland)

^d UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P40; TRANSCRIPTION FACTOR PU 1;

ARTICLE; BINDING AFFINITY; BINDING SITE; BONE MARROW CELL; CELL DIFFERENTIATION; GENE ACTIVITY; GENE DELETION; GENE EXPRESSION; GENE MUTATION; GENE OVEREXPRESSION; GRANULOPOIESIS; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA BINDING; TRANSCRIPTION REGULATION;

EID: 0037097733     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.V99.12.4578     Document Type: Article

References (70)

1. NADPH oxidase: An update
2. Activation of the neutrophil respiratory burst oxidase
3. Genetic, biochemical, and clinical teatures of chronic granulomatous disease
4. Oxygen metabolism and the toxic properties of phagocytes
5. Extracellular effects of the myeloperoxidase-hydrogen peroxide-halide system
6. Tissue destruction by neutrophils
7. Interactions between the components of the human NADPH oxidase: Intrigues in the phox family
8. Assembly of the phagocyte NADPH oxidase: Molecular interaction of oxidase proteins
9. Two cytosolic neutrophil oxidase components absent In autosomal chronic granutomatous disease
10. Two forms of autosomal chronic granulomatous disease lack distinct neutrophil cytosol factors
11. Cloning of the cDNA and functional expression of the 47 kilodalton cytosolic component of the human neutrophil respiratory burst oxidase
12. ract
13. 558-+ the flavin-binding component of the phagocyte NADPH oxidase
14. -245 is a flavocytochrome containing FAD and the NADPH-binding site of the microbicidal oxidase of phagocytes
15. Purification and characterization of Rac 2: A cytosotic GTP-binding protein that regulates human neutrophil NADPH oxidase
16. In vitro molecular reconstitution of the respiratory burst in B lymphoblasts from p47-phox-deficient chronic granulomatous disease
17. Peripheral blood progenitors as a target for genetic correction of p47 phox-deficient chronic granulomatous disease
18. 558 defective forms of chronic granulomatous disease
19. Retrovirus-mediated reconstitution of respiratory burst activity in X-linked chronic granulomatous disease cells
20. p22-phox-deficient chronic granulomatous disease: Reconstitution by retrovirus-mediated expression and identification of a biosynthetic intermediate of gp91-phox
21. Purification of the 260 kDa cytosolic complex involved in the superoxide production of guinea pig neutrophils
22. phox, a third cytosolic component of the activation complex of the NADPH oxidase to contain src homology 3 domains
23. phox
24. phox of the neutrophil oxidase complex using the two-hybrid system
25. phox
26. Topological organization of the cytosolic activating complex of the superoxide-generating NADPHoxidase: Pinpointing the sites of interaction between p47phox, p67phox and p40phox using the two-hybrid system
27. phox
28. phox
29. phox down-regulates NADPH oxidase activity through interactions with its SH3 domain
30. SH3 domain-mediated interactions involving the phox components of the NADPH oxidase
31. Rac1 disrupts p67phox/p40phox binding: A novel role for Rac in NADPH oxidase activation
32. 558
33. Cytosolic phox proteins interact with and regulate the assembly ot coronin in neutrophils
34. The 40-kDa component of the phagocyte NADPH oxidase (p40phox) is phosphorylated during activation in differentiated HL60 cells
35. phox phosphorylated on threonine 154 and serine 315 during activation of the phagocyte NADPH oxidase: Implication of a protein kinase C type kinase in the phosphorylation process
36. Genomic structure, chromosomal localization, start of transcription and tissue expression of the human p40-phox, a new component of the nicotinamide adenine dinucleotide phosphate-oxidase complex
37. phox, SH3-domain-containing proteins, involved in the phagocyte NADPH oxidase complex
38. Terminal myeloid gene expression and differentiation requires the transcription factor PU.1
39. Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages
40. Targeted disruption of the PU.1 gene results in multiple hematopoietic abnormalities
41. phox promoter activity in myeloid cells
42. The macrophage and B cellspecific transcription factor PU.1 is related to the ets oncogene
43. Analysis of the Bruton's tyrosine kinase gene promoter reveals critical PU.1 and SP1 sites
44. Subcellular localization of the b-cytochrome component of the human neutrophil microbicidal oxidase: Translocation during activation
45. c-Myc target gene specificity is determined by a post-DNA binding mechanism
46. Critical flanking sequences of PU.1 binding sites in myeloid-specific promoters
47. Normal functional characteristics of cultured human promyelocytic leukemia cells (HL-60) afer induction of differentiation by dimethyl sulfoxide
48. Analysis of commitment of human leukemia HL-60 cells to terminal granulocytic maturation
49. Induction of the respiratory burst in HL-60 cells: Correlation of function and protein expression
50. Evaluation of the expression of NADPH oxidase components during maturation of HL-60 cells to neutrophil lineage
51. The PU.1 transcription factor is the product of the putative oncogene Spi-1
52. Mouse beta-globin DNA-binding protein B1 is identical to a proto-oncogene, the transcription factor Spi-1/ PU.1, and is restricted in expression to hematopoietic cells and the testis
53. Hematopoietic lineage- and stage-restricted expression of the ETS oncogene family member PU.1
54. phox expression
55. phox gene in human peripheral neutrophils, monocytes, and B lymphocytes
56. phox via a promoter element mutated in a subset of chronic granulomatous disease patients
57. phox expression
58. Transcriptional regulalion o1 The p67phox gene: Role of AP-1 in concert with myeloid-specific transcription factors
59. phox promoter activity
60. 2 leukocyte integrin) promoter requires PU.1 transcription factor for myeloid activity
61. PU.1 (Spi-1) autoregulates its expression in myeloid cells
62. Regulation of B lymphocyte and macrophage development by graded expression of PU.1
63. 3 in monocytic U937 cells
64. phoX subunlts
65. Cellspecific expression of the macrophage scavenger receptor gene is dependent on PU.1 and a composite AP-1/ets motif
66. Pip, a novel IRF family member, is a lymphold-specific, PU.1-dependent transcriptional activator
67. Differential phosphorylations of Spi-B and Spi-1 transcription factors
68. Stimulation of macrophages by lipopolysaccharide alters the phosphorylation state, conformation, and function of PU.1 via activation of casein kinase II
69. Temporal mapping of gene expression levels during the differentiation of individual primary hematopoietic cells
70. Inhibition of hematopoiesis by competilive binding of Iranscription faclor PU.1