7-Hydroxytryptophan, a novel, specific, cytotoxic agent for carcinoids and other serotonin-producing tumors

Cancer

Volumn 94, Issue 12, 2002, Pages 3135-3140

  Walther, Diego J ^a   Peter, Jens Uwe ^a   Bader, Michael ^a  

^a MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

Author keywords

7 Hydroxytryptophan; Carcinoid tumor; Small cell lung carcinoma; Suicide prodrug; Tryptophan hydroxylase

Indexed keywords

5,7 DIHYDROXYTRYPTAMINE; 7 HYDROXYTRYPTOPHAN; CYCLOPHOSPHAMIDE; CYTOTOXIC AGENT; DOXORUBICIN; FENCLONINE; FLUOROURACIL; SEROTONIN; SEROTONIN ANTAGONIST; STREPTOZOCIN; TRYPTOPHAN HYDROXYLASE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; AUTOCRINE EFFECT; CANCER CELL CULTURE; CANCER CHEMOTHERAPY; CARCINOID; CENTRAL NERVOUS SYSTEM DISEASE; CONTROLLED STUDY; DRUG EFFICACY; DRUG METABOLISM; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; LUNG NON SMALL CELL CANCER; PRIORITY JOURNAL; PROTEIN EXPRESSION; TREATMENT OUTCOME;

5,6-DIHYDROXYTRYPTAMINE; 5,7-DIHYDROXYTRYPTAMINE; ANIMALS; ANTINEOPLASTIC AGENTS; CARCINOID TUMOR; CARCINOMA, SMALL CELL; COS CELLS; HUMANS; LUNG NEOPLASMS; PANCREATIC NEOPLASMS; SEROTONIN; TRYPTOPHAN; TRYPTOPHAN HYDROXYLASE; TUMOR CELLS, CULTURED;

EID: 0037096856     PISSN: 0008543X     EISSN: None     Source Type: Journal    
DOI: 10.1002/cncr.10592     Document Type: Article

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