Determination of betamethasone disodium phosphate in the in vitro media of PLGA microspheres by high-performance liquid chromatography

Journal of Pharmaceutical and Biomedical Analysis

Volumn 28, Issue 3-4, 2002, Pages 629-635

  Wang, Ling ^a   Yang, Yi Yan ^a   Chung, Tai Shung ^a,b   Chen, Xue Qin ^a  

^a INSTITUTE OF MATERIALS RESEARCH AND ENGINEERING   (Singapore)

^b Department of Chemical and Environmental Engineering ^*  (Singapore)

Author keywords

Betamethasone disodium phosphate; High performance liquid chromatography; PLGA microspheres; Stability; Validation

Indexed keywords

ACETONITRILE; BETAMETHASONE SODIUM PHOSPHATE; MICROSPHERE; PHOSPHORIC ACID; POLYGLACTIN; POLYMER; WATER;

ACCURACY; ANALYTICAL EQUIPMENT; ARTICLE; CONCENTRATION (PARAMETERS); CORRELATION ANALYSIS; DRUG DETERMINATION; DRUG STABILITY; FLOW RATE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; INJECTION; INTERMETHOD COMPARISON; PARTICULATE MATTER; PH; PRIORITY JOURNAL; SUSTAINED RELEASE PREPARATION; TEMPERATURE; TIME; VALIDATION PROCESS;

ANTI-INFLAMMATORY AGENTS; BETAMETHASONE; CALIBRATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG STABILITY; EXCIPIENTS; HYDROGEN-ION CONCENTRATION; LACTIC ACID; MASS SPECTROMETRY; MICROSPHERES; POLYGLYCOLIC ACID; POLYMERS; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS;

EID: 0037093671     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0731-7085(01)00667-7     Document Type: Article

References (13)