A strategy for examining complex mixtures of deoxyoligonucleotides using ion-pair-reverse-phase high-performance liquid chromatography, matrix-assisted laser desorption ionization time-of-flight mass spectrometry, and informatics

Analytical Biochemistry

Volumn 304, Issue 2, 2002, Pages 257-265

  Vallone, Peter M ^a   Devaney, Joseph M ^b   Marino, Michael A ^b   Butler, John M ^a  

^a NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY   (United States)

^b TRANSGENOMIC INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOINFORMATICS; DESORPTION; DRUG PRODUCTS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INDUCTIVELY COUPLED PLASMA; INFORMATICS; IONIZATION OF LIQUIDS; NUCLEIC ACIDS;

COMPUTATIONAL ALGORITHM; DIGESTION PRODUCTS; INTEGRATED STRATEGY; ION-PAIR REVERSE-PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MATRIX-ASSISTED LASER DESORPTION-IONIZATION TIME-OF-FLIGHT MASS; NUCLEIC ACID OLIGOMERS; PARTIAL SEQUENCES; SEQUENCE IDENTITY;

MASS SPECTROMETRY;

OLIGODEOXYNUCLEOTIDE;

ANALYTIC METHOD; ANIMAL CELL; ARTICLE; COMPLEX FORMATION; DIAGNOSTIC TEST; DNA DETERMINATION; INFORMATION SCIENCE; MASS SPECTROMETRY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; METHODOLOGY; NONHUMAN; PRIORITY JOURNAL; QUALITY CONTROL; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SCREENING; TECHNIQUE;

EID: 0037092985     PISSN: 00032697     EISSN: None     Source Type: Journal    
DOI: 10.1006/abio.2002.5641     Document Type: Article

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