Protease action and generation of β-thromboglobulin-like protein followed by platelet activation

Thrombosis Research

Volumn 106, Issue 4-5, 2002, Pages 229-236

  Resmi, K R ^a   Krishnan, L K ^a  

^a SREE CHITRA TIRUNAL INSTITUTE FOR MEDICAL SCIENCES AND TECHNOLOGY   (India)

Author keywords

Granule secretion; thromboglobulin; Metal dependent proteases; Platelet activation

Indexed keywords

ADENOSINE DIPHOSPHATE; BENZYLSULFONYL FLUORIDE; BETA THROMBOGLOBULIN; CHELATING AGENT; EDETIC ACID; EGTAZIC ACID; PROTEINASE; THROMBOCYTE ACTIVATING FACTOR; METAL; METALLOPROTEINASE; PROTEIN PRECURSOR;

ARTICLE; CELL STIMULATION; CONTROLLED STUDY; ENZYME INHIBITION; HUMAN; HYBRIDOMA; KINETICS; MOLECULAR WEIGHT; MOUSE; NONHUMAN; NORMAL HUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN SECRETION; THROMBOCYTE ACTIVATION; WESTERN BLOTTING; BIOSYNTHESIS; ENZYMOLOGY; METABOLISM; SECRETORY VESICLE; THROMBOCYTE; ULTRASTRUCTURE;

BETA-THROMBOGLOBULIN; BLOOD PLATELETS; CHELATING AGENTS; ENDOPEPTIDASES; HUMANS; METALLOENDOPEPTIDASES; METALS; MOLECULAR WEIGHT; PLATELET ACTIVATION; PROTEIN PRECURSORS; SECRETORY VESICLES;

EID: 0037092642     PISSN: 00493848     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0049-3848(02)00135-4     Document Type: Article

References (26)

1. Moore S., Pepper D.S., Cash J.D. The isolation and characterization of a platelet-specific β-globulin (β-thromboglobulin) and detection of antiurokinase and antiplasmin released from thrombin aggregated washed human platelets. Biochim. Biophys. Acta. 379:1975;360-369.
2. Begg G.S., Pepper D.S., Chesterman C.N., Morgan F.J. Complete covalent structure of human β-thromboglobulin. Biochemistry. 17(9):1978;1739-1744.
3. Niewiarowski S., Paul D. Platelet granule proteins with mitogenic and antiheparin activity. Gordon J.L. Platelets in Biology and Pathology. 1981;91-103 Elsevier, Amsterdam.
4. Kaplan K.L., Broekman M.J., Chernoff A., Lesznik G.R., Drillings M. Platelet α-granule proteins: studies on release and subcellular localization. Blood. 53(4):1979;604-618.
5. Niewiarowski D.A., Daniel A., James P., Rucinski B., Kueppers F. Identification and separation of secreted platelet proteins by isoelectric focusing. Evidence that LA-PF4 is converted to β-TG by limited proteolysis. Blood. 55:1980;453-456.
6. Kaplan K.L., Niewiarowski S. Nomenclature of secreted platelet proteins - report of the working party on secreted platelet proteins of the subcommittee on platelets. Thromb. Haemost. 53:1985;282-284.
7. Brandt E., Ludwig A., Petersen F., Flad H.D. Platelet-derived CXC chemokines: old players in new games. Immunol. Rev. 177:2000;204-216.
8. Wenger R.H., Hameister H., Clemetson K.J. Human platelet basic protein/CTAP III maps in a gene cluster on chromosome 4q12-q13 along with other genes of the beta-TG superfamily. Hum. Genet. 87(3):1991;367-368.
9. Castor C.W., Miller J.W., Walz D.A. Structural and biological characteristics of connective tissue activating peptide (CTAP-III), a major human platelet-derived growth factor. Proc. Natl. Acad. Sci. U. S. A. 80(3):1983;765-769.
10. Hjemdahl P., Perneby C., Theodorsson E.N., Egberg, Larsso P.T. A new assay for β-thromboglobulin in urine. Thromb. Res. 64:1991;33-43.
11. Senior R.M., Griffin G.L., Huang J.S., Walz D.A., Deuel J. Chemotactic activity of platelet alpha granule proteins for fibroblasts. J. Cell Biol. 96:1983;382.
12. Brandt E., Peterson F., Ludwig A., Ehlert J.E.et al. The beta-thromboglobulin and platelet factor-4 blood platelet derived CXC chemokines with divergent roles in early neutrophil regulation. J. Leukoc. Biol. 67(4):2000;471-478.
13. Fox J.E.B. Identification of actin binding protein as the protein linking the membrane skeleton to glycoproteins on platelet plasma membranes. J. Biol. Chem. 260:1985;11970-11977.
14. Tangen O., Berman H.J., Marphy P. Gel filtration. A new technique for separation of blood platelets from plasma. Thromb. Diath. Haemorrh. 25:1971;268-278.
15. Lowry O.H., Rosebrough N.J., Farr A.L., Randall R.J. Protein measurement with the folin phenol reagent. J. Biol. Chem. 193:1951;265-275.
16. Laemmli U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature. 227:1970;680-685.
17. Morrissey J.H. Silver staining of proteins in polyacrylamide gels: a modified procedure with enhanced uniform sensitivity. Anal. Biochem. 117:1981;307-310.
18. Rucinski B., Niewiarowski S., James P., Walz D.A., Budzynski A.Z. Antiheparin proteins secreted by human platelets: purification, characterization and radioimmunoassay. Blood. 53:1979;47-62.
19. Kohn J., Wilchek M. Procedures for analysis of cyanogens bromide-activated sepharose or sephadex by quantitative determination of cyanate esters and imidocarbonates. Anal. Biochem. 115:1981;375-382.
20. Kohn J., Wilchek M. A new approach (cyano transfer) for cyanogen bromide activation of sepharose at neutral pH, which yields activated resins, free of interfering nitrogen derivatives. Biochem. Biophys. Res. Commun. 107:1982;878-884.
21. Hager D.A., Burgess R.R. Elution of proteins from sidium dodycylsulphate p-polyacrylamide gels, removal of sodium dodycyl sulphate, and renaturation of enzymatic activity; results with sigma subunit of E. coli RNA polymerase, wheat germ DNA topoisomerase and other enzymes. Anal. Biochem. 109:1980;76-86.
22. Harlow E., Lane D. Antibodies. A Laboratory Manual. 1988;139-238 Cold Spring Harbor Laboratory, US.
23. Hallam T.J., Rink T.J. Agonists stimulate divalent cation channels in the plasma membrane of human platelets. FEBS Lett. 186:1985;175-179.
24. 2+-dependent protease in human platelets. J. Biol. Chem. 252:1977;5602-5605.
25. Ogston D.M., Murray J., Douglas A.S. Br. J. Haematol. 24:1973;665-666.
26. Holt J.C., Niewiarowski S. Biochemistry of alpha granule proteins. Semin. Hematol. 22(2):1985;151-163.