Pharmacogenetics place in modern medical science and practice

Life Sciences

Volumn 70, Issue 13, 2002, Pages 1471-1480

  Roses, Allen D ^a  

^a GLAXOSMITHKLINE   (United States)

Author keywords

Mapping; Pharmaceuticals; Pharmacogenetics; Targets

Indexed keywords

ABACAVIR; ABACAVIR PLUS LAMIVUDINE PLUS ZIDOVUDINE; APOLIPOPROTEIN C1; APOLIPOPROTEIN E3; APOLIPOPROTEIN E4;

CLINICAL TRIAL; COST; DNA SCREENING; DNA SEQUENCE; DRUG FORMULATION; DRUG INDUSTRY; DRUG TARGETING; GENE MAPPING; GENETIC VARIABILITY; GENOTYPE; HUMAN; HYPERSENSITIVITY; MEDICAL PRACTICE; MEDICINE; PHARMACOGENETICS; RISK BENEFIT ANALYSIS; SCREENING; SHORT SURVEY; SINGLE NUCLEOTIDE POLYMORPHISM;

EID: 0037083874     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0024-3205(01)01532-6     Document Type: Review

References (23)

1. Drug discovery: A historical perspective
2. Alternative strategies in drug development: Clinical pharmacological aspects
3. Apolipoprotein E alleles as risk factors in Alzheimer's disease
4. Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease
5. Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease
6. Genomics in the real world
7. Apolipoprotein E is a relevant susceptibility gene that affects the rate of expression of Alzheimer's disease
8. The essence of SNPs
9. Single nucleotide polymorphisms: From the evolutionary past
10. Specificity, sensitivity, and predictive value of apolipoprotein-E genotyping for sporadic Alzheimer's disease
11. Genetic epidemiology of single-nucleotide polymorphisms
12. A 4-Mb high-density single nucleotide polymorphism-based map around human APOE
13. SNPing away at complex diseases: Analysis of single-nucleotide polymorphisms around APOE in Alzheimer disease
14. Pharmacogenetics and the practice of medicine
15. Identification of a psoriasis susceptibility candidate gene by linkage disequilibrium mapping with a localised single nucleotide polymorphism map
16. Single nucleotide polymorphism (SNP) alleles in the Insulin Receptor (INSR) gene confer susceptibility to migraine
17. Prospects for whole-genome linkage disequilibrium mapping of common disease genes
18. Pharmacogenetics and future drug development and delivery
19. A map of human genome sequence variation containing 1.42 million single nucleotide polymorphisms
20. Abacavir
21. Genomic medicine and the future of health care
22. Influence of the susceptibility genes apolipoprotein E-epsilon 4 and apolipoprotein E-epsilon 2 on the rate of disease expressivity of late-onset Alzheimer's disease