Deletion allele of the angiotensin-converting enzyme gene as a risk factor for pneumonia in elderly patients

American Journal of Medicine

Volumn 112, Issue 2, 2002, Pages 89-94

  Morimoto, Shigeto ^a,b   Okaishi, Kohya ^a   Onishi, Miyuki ^a   Katsuya, Tomohiro ^a   Yang, Jin ^a   Okuro, Masashi ^a   Sakurai, Shoroku ^a   Onishi, Toshio ^a   Ogihara, Toshio ^a  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DIPEPTIDYL CARBOXYPEPTIDASE;

AGED; ALLELE; ARTICLE; CONTROLLED STUDY; FEMALE; FOLLOW UP; GENE DELETION; GENE FREQUENCY; GENETIC POLYMORPHISM; GENOTYPE; HOSPITAL PATIENT; HUMAN; INCIDENCE; LONG TERM CARE; MAJOR CLINICAL STUDY; MALE; PNEUMONIA; PRIORITY JOURNAL; RISK FACTOR;

AGED; AGED, 80 AND OVER; ALLELES; FEMALE; FOLLOW-UP STUDIES; GENE DELETION; GENE FREQUENCY; GENOTYPE; HUMANS; INCIDENCE; JAPAN; MALE; PEPTIDYL-DIPEPTIDASE A; PNEUMONIA; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; PROPORTIONAL HAZARDS MODELS; RISK FACTORS;

EID: 0037083236     PISSN: 00029343     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9343(01)01071-3     Document Type: Article

References (32)

1. Sensitivity of the cough reflex in young and elderly subjects
2. Lack of cough reflex in aspiration pneumonia
3. Role of substance P in cough
4. High incidence of silent aspiration in elderly patients with community-acquired pneumonia
5. Angiotensin converting enzyme and the cough reflex
6. Sputum substance P in aspiration pneumonia
7. Bradykinin-evoked sensitization of airway sensory nerves. A mechanism for ACE-inhibitor cough
8. Reduction of risk of pneumonia associated with use of angiotensin I converting enzyme inhibitors in elderly inpatients
9. ACE inhibitors, and pneumonia
10. ACE inhibitors, and pneumonia in elderly people
11. ACE inhibitors and prevention of aspiration pneumonia in elderly hypertensives
12. An insertion/deletion polymorphism in the angiotensin I-converting enzyme gene accounting for half the variance of serum enzyme levels
13. Identification of new polymorphisms of the angiotensin I-converting enzyme (ACE) gene, and study of their relationship to plasma ACE levels by two-QTL segregation-linkage analysis
14. ACE insertion/deletion genotype affects bradykinin metabolism
15. Angiotensin-I-converting enzyme gene polymorphism, and susceptibility to cough
16. Human ACE gene polymorphism and distilled water induced cough
17. The DD-ACE genotype and cardiovascular disease
18. High frequency of a deletion polymorphism of the angiotensin-converting enzyme gene in asthma
19. The angiotensin-converting enzyme DD gene is associated with poor prognosis in Finnish sarcoidosis patients
20. Risk factors for pneumonia in the elderly
21. CDC definitions for nosocomial infections
22. Risk factors for pneumonia and other lower respiratory tract infections in elderly residents of long-term care facilities
23. Mistyping ACE hetorozygotes
24. A prospective evaluation of an angiotensin-converting-enzyme gene polymorphism and the risk of ischemic heart disease
25. Rapid detection of the hypertension-associated Met235Thr allele of the human angiotensinogen gene
26. Angiotensin II type 1 receptor gene polymorphism is associated with increase of left ventricular mass but not with hypertension
27. Regression models and life tables
28. Simulation study of confounder-selection strategies
29. Deletion allele of angiotensin-converting enzyme gene increases risk of essential hypertension in Japanese men: The Suita study
30. Genetic associations with human longevity at the APOE and ACE loci
31. Clinical manifestations and consequences of influenza
32. Angiotensin I-converting enzyme, and plasminogen activator inhibitor-1 gene variants: Risk of mortality and fatal cardiovascular disease in an elderly population-based cohort