Infection and nitric oxide

Journal of Infectious Diseases

Volumn 185, Issue SUPPL. 1, 2002, Pages

  Hibbs Jr , John B ^a  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; CYTOKINE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE;

CELLULAR IMMUNITY; CITRIC ACID CYCLE; CONFERENCE PAPER; CYTOTOXICITY; ELECTRON TRANSPORT; LISTERIA MONOCYTOGENES; MACROPHAGE ACTIVATION; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; TOXOPLASMA GONDII;

ANIMALS; CYTOKINES; HISTORY, 20TH CENTURY; INFECTION; MACROPHAGE ACTIVATION; MACROPHAGES, PERITONEAL; MICE; MICE, INBRED BALB C; MICE, INBRED C3H; NITRIC OXIDE;

EID: 0037083160     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/338005     Document Type: Conference Paper

References (48)

1. Resistance to intracellular infection
2. Immunity and intracellular infection: Resistance to bacteria in mice infected with a protozoan
3. Resistance to virus challenge in mice infected with protozoa or bacteria
4. Studies on the mechanisms of resistance to phylogenetically diverse intracellular organisms
5. Resistance to murine tumors conferred by chronic infection with intracellular protozoa, Toxoplasma gondii and Besnoitia jellisoni
6. Possible role of macrophage mediated nonspecific cytotoxicity in tumor resistance
7. Control of carcinogenesis: A possible role of the activated macrophage
8. In vitro nonimmunologic destruction of cells with abnormal growth characteristics by adjuvant activated macrophages
9. Macrophage tumor killing: Influence of the local environment
10. Modulation of macrophage tumoricidal capability by components of normal serum: A central role for lipid
11. Characterization of the effects of endotoxin on macrophage tumor cell killing
12. Functional characterization of a stable, noncytolytic stage of macrophage activation in tumors
13. Macrophage activation for tumor cytotoxicity: Development of macrophage cytotoxic activity requires completion of a sequence of short-lived intermediary reactions
14. Cytostatic elimination of syngeneic rat tumor cells in vitro by non-specifically activated macrophages
15. The role of activated macrophages in specific and nonspecific cytostasis of tumor cells
16. Injury of neoplastic cells by murine macrophages leads to inhibition of mitochondrial respiration
17. Iron depletion: Possible cause of tumor cell cytotoxicity induced by activated macrophages
18. Murine cytotoxic activated macrophages inhibit aconitase in tumor cells. Inhibition involves the iron-sulfur prosthetic group and is reversible
19. Sites of inhibition of mitochondrial electron transport in macrophage-injured neoplastic cells
20. Endocytosis of red blood cells or haemoglobin by activated macrophages inhibits their tumoricidal effect
21. L-Arginine is required for expression of the activated macrophage effector mechanism causing selective metabolic inhibition in target cells
22. Macrophage cytotoxlicity: Role for L-arginine deiminase activity and imino nitrogen oxidation to nitrite
23. Mammalian nitrate biosynthesis: Mouse macrophages produce nitrite and nitrate in response to Escherichia coli lipopolysaccharide
24. Macrophage synthesis of nitrite, nitrate, and N-nitrosamines: Precursors and role of the respiratory burst
25. Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor
26. Endothelium-derived relaxing factor from pulmonary artery and vein possesses pharmacological and chemical properties that are identical to those for nitric oxide radical
27. Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide
28. Vascular endothelial cells synthesize nitric oxide from L-arginine
29. Nitric oxide: A cytotoxic activated macrophage effector molecule
30. Macrophage oxidation of L-arginine to nitrite and nitrate: Nitric oxide is an intermediate
31. Interferon-gamma and tumor necrosis factor induce the L-arginine-dependent cytotoxic effector mechanism in murine macrophages
32. Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages
33. Differentiation of murine macrophages to express nonspecific cytotoxicity for tumor cells results in L-arginine-dependent inhibition of mitochondrial iron-sulfur enzymes in the macrophage effector cells
34. The L-arginine dependent effector mechanism is induced in murine adenocarcinoma cells by culture supernatant from cytotoxic activated macrophages
35. Cytokines induce an L-arginine-dependent effector system in nonmacrophage cells
36. Specific amino acid (L-arginine) requirement for the microbiostatic activity of murine macrophages
37. NMDA receptor activation induces nitric oxide synthesis from L-arginine in rat brain slices
38. Nitric oxide in listeriosis
39. Reactive oxygen and nitrogen intermediates in the relationship between mammalian hosts and microbial pathogens
40. Evidence for cytokine-inducible nitric oxide synthesis from L-arginine in patients receiving interleukin-2 therapy
41. Urinary nitrate excretion in relation to murine macrophage activation
42. Effect of in vivo inhibition of nitric oxide production in murine leishmaniasis
43. Human mononuclear phagocyte nitric oxide production and inducible nitric oxide synthase expression
44. Molecular regulation of the human inducible nitric oxide synthase (iNOS) gene
45. Chemical biology of nitric oxide: Insights into regulatory, cytotoxic and cytoprotective mechanisms of nitric oxide
46. EPR demonstration of iron-nitrosyl complex formation by cytotoxic activated macrophages
47. IFN-gamma activated macrophage: Detection by electron paramagnetic resonance of complexes between L-arginine-derived nitric oxide and non-heme iron proteins
48. Induction of iron-derived EPR signals in murine cancers by nitric oxide