Phase II and biologic study of interferon alfa, retinoic acid, and cisplatin in advanced squamous skin cancer

Journal of Clinical Oncology

Volumn 20, Issue 2, 2002, Pages 364-370

  Shin, Dong M ^a   Glisson, Bonnie S ^a   Khuri, Fadlo R ^a   Clifford, John L ^a   Clayman, Gary ^a   Benner, Steven E ^a   Forastiere, Arlene A ^a   Ginsberg, Lawrence ^a   Liu, Diane ^a   Lee, J Jack ^a   Myers, Jeffrey ^a   Goepfert, Helmuth ^a   Lotan, Reuben ^a   Hong, Waun Ki ^a   Lippman, Scott M ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; CISPLATIN; ISOTRETINOIN; RETINOIC ACID;

ADULT; ADVANCED CANCER; AGED; ANEMIA; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER CHEMOTHERAPY; CANCER INHIBITION; CANCER SURVIVAL; CELL CYCLE; CLINICAL ARTICLE; CLINICAL TRIAL; DRUG MIXTURE; FATIGUE; FEBRILE NEUTROPENIA; FEMALE; HUMAN; HUMAN CELL; HYPERTRIGLYCERIDEMIA; MALE; METASTASIS; NEUTROPENIA; PERIPHERAL NEUROPATHY; PHASE 2 CLINICAL TRIAL; PRIORITY JOURNAL; SKIN CANCER; SQUAMOUS CELL CARCINOMA; SURVIVAL RATE; THROMBOCYTOPENIA; VOMITING; XEROSTOMIA;

ADULT; AGED; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; APOPTOSIS; CARCINOMA, SQUAMOUS CELL; CELL CYCLE; CISPLATIN; FATIGUE; FEMALE; FEVER; HUMANS; INJECTIONS, INTRAVENOUS; INJECTIONS, SUBCUTANEOUS; INTERFERON-ALPHA; ISOTRETINOIN; MALE; MIDDLE AGED; NEUTROPENIA; SKIN NEOPLASMS; SURVIVAL ANALYSIS; TREATMENT OUTCOME; TUMOR CELLS, CULTURED;

EID: 0037080124     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/JCO.20.2.364     Document Type: Article

References (34)

1. Cutaneous squamous-cell carcinoma
2. Increase in incidence rates of basal cell and squamous cell skin cancer in New Hampshire, USA: New Hampshire Skin Cancer Study Group
3. Chemotherapy and biologic response modifiers for advanced disease, part III: Squamous cell carcinoma
4. Nonsurgical treatments for skin cancer: Retinoids and alpha-interferon
5. Retinoids as preventive and therapeutic anticancer agents
6. Preoperative treatment of advanced skin carcinoma with cisplatin and bleomycin
7. Combination chemotherapy of head and neck cancer
8. Cisplatin-based chemotherapy in advanced basal and squamous cell carcinoma of the skin: Results in 28 patients including 13 patients receiving multimodality therapy
9. Treatment of advanced squamous cell carcinoma of the skin with cisplatin, 5-fluorouracil, and bleomycin
10. 13-cis-retinoic acid and interferon alpha-2a: Effective combination therapy for advanced squamous cell carcinoma of the skin
11. Antineoplastic activity of the combination of interferon and cytotoxic agents against experimental and human malignancies: A review
12. Retinoids and interferons: Combination studies in human cancer
13. A phase I trial of recombinant alpha-2a interferon (Roferon-A) with weekly cisplatinum
14. Phase I study of treatment with oral 13-cis-retinoic acid, subcutaneous interferon alfa-2a, cisplatin, and 24-hour infusion 5-fluorouracil/leucovorin
15. 13-cis retinoic acid exerts its specific activity on human sebocytes through selective intracellular isomerization to all-trans retinoic acid and binding to retinoid acid receptors
16. Phase I trial and pharmacokinetic study of all-trans-retinoic acid administered on an intermittent schedule in combination with interferon-alpha 2a in pediatric patients with refractory cancer
17. Phase I clinical and pharmacologic study of 13-cis-retinoic acid, interferon alfa, and paclitaxel in patients with prostate cancer and other advanced malignancies
18. Interferon alfa-2a and 13-cis-retinoic acid in renal cell carcinoma: Antitumor activity in a phase II trial and interactions in vitro
19. Multicenter phase II trial of interleukin-2, interferon-alpha, and 13-cis-retinoic acid in patients with metastatic renal cell carcinoma
20. Phase III trial of interferon alfa-2a with or without 13-cis-retinoic acid for patients with advanced renal cell carcinoma
21. 13-Cisretinoic acid plus interferon-alpha 2A in locally advanced squamous cell carcinoma of the cervix
22. Combined interferon-alfa, 13-cis-retinoic acid and alpha-tocopherol in locally advanced head and neck squamous cell carcinoma: Novel bioadjuvant phase II trial
23. Treatment of high-risk neuroblastoma with intensive chemotherapy, radiotherapy, autologous bone marrow transplantation, and 13-cis-retinoic acid: Children's Cancer Group
24. Reporting results of cancer treatment
25. Nonparametric estimation from incomplete observations
26. Comprehensive criteria for assessing therapy-induced toxicity
27. Probes for live cell function
28. Retinoid receptor-dependent and -independent effects of N-(4-hydroxyphenyl)retinamide in F 9 embryonal carcinoma cells
29. RXRalpha-null F9 embryonal carcinoma cells are resistant to the differentiation, antiproliferative and apoptotic effects of retinoids
30. Carcinoma of the skin (excluding eyelid, vulva, and penis)
31. Induction of apoptotic cell death in non-melanoma skin cancer by interferon-α
32. Expression of protein mediators of type I interferon signaling in human squamous cell carcinoma of the skin
33. Progressive decreases in nuclear retinoid receptors during skin squamous cell carcinogenesis
34. Expression of a retinoid inducible tumor suppressor, tazarotene inducible gene-3, is decreased in psoriasis and skin cancer