MMP-8: A new target for atherosclerosis?

Drug Discovery Today

Volumn 7, Issue 2, 2002, Pages 86-88

  Fricker, Janet ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA ACTIN; CD40 ANTIGEN; CHLORDANE; COLLAGEN TYPE 1; COLLAGENASE 3; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; INTERLEUKIN 1BETA; INTERSTITIAL COLLAGENASE; LOW DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN RECEPTOR; METALLOPROTEINASE INHIBITOR; NEUTROPHIL COLLAGENASE; STATIN; TUMOR NECROSIS FACTOR ALPHA;

ARTERY THROMBOSIS; ATHEROGENESIS; ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; DNA MICROARRAY; DRUG EFFECT; DRUG TARGETING; ENZYME ACTIVITY; ENZYME INHIBITION; GENE EXPRESSION; HEART INFARCTION; HUMAN; LIVER DISEASE; MUSCLE DISEASE; PROTEIN EXPRESSION; SHORT SURVEY; STROKE; ARTERIOSCLEROSIS; ARTICLE; DRUG ANTAGONISM; GENETICS; PHYSIOLOGY;

ARTERIOSCLEROSIS; HUMAN; NEUTROPHIL COLLAGENASE; HUMANS; MATRIX METALLOPROTEINASE 8;

EID: 0037079602     PISSN: 13596446     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1359-6446(01)02148-1     Document Type: Short Survey

References (5)

1. Expression of neutrophil collagenase (matrix metalloproteinase-8) in human atheroma: A novel collagenolytic pathway suggested by transcriptional profiling
2. Risk of thrombosis in human atherosclerotic plaques: Role of extracellular lipid, macrophage, and smooth muscle cell content
3. Role of inflammation and metalloproteinases in plaque disruption and thrombosis
4. Development of matrix metalloproteinase inhibitors in cancer therapy
5. Matrix metalloproteinase hypothesis of plaque rupture: Players keep piling up but questions remain