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Volumn 159, Issue 1, 2002, Pages 79-89

Calcium-regulated exocytosis of dense-core vesicles requires the activation of ADP-ribosylation factor (ARF)6 by ARF nucleotide binding site opener at the plasma membrane

Author keywords

ARF6; Exocytosis; PC12 cells; Phospholipase D; Secretory granule

Indexed keywords

ADENOSINE DIPHOSPHATE RIBOSYLATION FACTOR; ADENOSINE DIPHOSPHATE RIBOSYLATION FACTOR 6; CALCIUM; GUANINE NUCLEOTIDE EXCHANGE FACTOR; MEMBRANE PHOSPHOLIPID; PHOSPHOLIPASE D1; PROTEIN ARNO; UNCLASSIFIED DRUG;

EID: 0037078319     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.200203027     Document Type: Article
Times cited : (104)

References (54)
  • 1
    • 0030891289 scopus 로고    scopus 로고
    • N-terminal hydrophobic residues of the G-protein ADP-ribosylation factor-1 insert into membrane phospholipids upon GDP to GTP exchange
    • Antonny, B., S. Beraud-Dufour, P. Chardin, and M. Chabre. 1997. N-terminal hydrophobic residues of the G-protein ADP-ribosylation factor-1 insert into membrane phospholipids upon GDP to GTP exchange. Biochemistry. 36:4675-4684.
    • (1997) Biochemistry , vol.36 , pp. 4675-4684
    • Antonny, B.1    Beraud-Dufour, S.2    Chardin, P.3    Chabre, M.4
  • 2
    • 0023757432 scopus 로고
    • The cytoskeleton as a barrier to exocytosis in secretory cells
    • Aunis, D., and M.F. Bader. 1988. The cytoskeleton as a barrier to exocytosis in secretory cells. J. Exp. Biol. 139:253-266.
    • (1988) J. Exp. Biol. , vol.139 , pp. 253-266
    • Aunis, D.1    Bader, M.F.2
  • 3
    • 0029881303 scopus 로고    scopus 로고
    • A role for ADP-ribosylation factor 1, but not COP I, in secretory vesicle biogenesis from the trans-Golgi network
    • Barr, F.A., and W.B. Hutmer. 1996. A role for ADP-ribosylation factor 1, but not COP I, in secretory vesicle biogenesis from the trans-Golgi network. FEBS Lett. 384:65-70.
    • (1996) FEBS Lett. , vol.384 , pp. 65-70
    • Barr, F.A.1    Hutmer, W.B.2
  • 5
    • 0035853270 scopus 로고    scopus 로고
    • G protein betagamma subunit-mediated presynaptic inhibition: Regulation of exocytotic fusion downstream of calcium entry
    • Blackmer, T., E.C. Larsen, M. Takahashi, T.F. Martin, S. Alford, and H.E. Hamm. 2001. G protein betagamma subunit-mediated presynaptic inhibition: regulation of exocytotic fusion downstream of calcium entry. Science. 292:293-297.
    • (2001) Science , vol.292 , pp. 293-297
    • Blackmer, T.1    Larsen, E.C.2    Takahashi, M.3    Martin, T.F.4    Alford, S.5    Hamm, H.E.6
  • 6
    • 0034095215 scopus 로고    scopus 로고
    • ADP-ribosylation factor 6 regulates actin cytoskeleton remodeling in coordination with Rac1 and RhoA
    • Boshans, R.L., S. Szanto, L. van Aelst, and C. D'Souza-Schorey. 2000. ADP-ribosylation factor 6 regulates actin cytoskeleton remodeling in coordination with Rac1 and RhoA. Mol. Cell. Biol. 20:3685-3694.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 3685-3694
    • Boshans, R.L.1    Szanto, S.2    Van Aelst, L.3    D'Souza-Schorey, C.4
  • 7
    • 0031889838 scopus 로고    scopus 로고
    • Regulated exocytosis in chromaffin cells. Translocation of ARF6 stimulates a plasma membrane-associated phospholipase D
    • Caumont, A.S., M.C. Galas, N. Vitale, D. Aunis, and M.F. Bader. 1998. Regulated exocytosis in chromaffin cells. Translocation of ARF6 stimulates a plasma membrane-associated phospholipase D. J. Biol. Chem. 273:1373-1379.
    • (1998) J. Biol. Chem. , vol.273 , pp. 1373-1379
    • Caumont, A.S.1    Galas, M.C.2    Vitale, N.3    Aunis, D.4    Bader, M.F.5
  • 8
    • 0034717061 scopus 로고    scopus 로고
    • Identification of a plasma membrane-associated guanine nucleotide exchange factor for ARF6 in chromaffin cells. Possible role in the regulated exocytotic pathway
    • Caumont, A.S., N. Vitale, M. Gensse, M.C. Galas, J.E. Casanova, and M.F. Bader. 2000. Identification of a plasma membrane-associated guanine nucleotide exchange factor for ARF6 in chromaffin cells. Possible role in the regulated exocytotic pathway. J. Biol. Chem. 275:15637-15644.
    • (2000) J. Biol. Chem. , vol.275 , pp. 15637-15644
    • Caumont, A.S.1    Vitale, N.2    Gensse, M.3    Galas, M.C.4    Casanova, J.E.5    Bader, M.F.6
  • 10
    • 0029844904 scopus 로고    scopus 로고
    • A human exchange factor for ARF proteins contains Sec7-and pleckstrin-homology domains
    • Chardin, P., S. Paris, B. Antonny, S. Béraud-Dufour, C.L. Jackson, and M. Chabre. 1996. A human exchange factor for ARF proteins contains Sec7-and pleckstrin-homology domains. Nature. 384:479-481.
    • (1996) Nature , vol.384 , pp. 479-481
    • Chardin, P.1    Paris, S.2    Antonny, B.3    Béraud-Dufour, S.4    Jackson, C.L.5    Chabre, M.6
  • 11
    • 0033180113 scopus 로고    scopus 로고
    • The role of ARF and Rab GTPases in membrane transport
    • Chavrier, P., and B. Goud. 1999. The role of ARF and Rab GTPases in membrane transport. Curr. Opin. Cell Biol. 11:466-475.
    • (1999) Curr. Opin. Cell Biol. , vol.11 , pp. 466-475
    • Chavrier, P.1    Goud, B.2
  • 14
    • 0033937941 scopus 로고    scopus 로고
    • Regulators and effectors of the ARF GTPases
    • Donaldson, J.G., and C.L. Jackson. 2000. Regulators and effectors of the ARF GTPases. Curr. Opin. Cell Biol. 12:475-482.
    • (2000) Curr. Opin. Cell Biol. , vol.12 , pp. 475-482
    • Donaldson, J.G.1    Jackson, C.L.2
  • 15
    • 0032498526 scopus 로고    scopus 로고
    • ARF6 targets recycling vesicles to the plasma membrane: Insights from an ultrastructural investigation
    • D'Souza-Schorey, C., E.L. Donselaar, V.W. Hsu, C.Y. Yang, P.D. Stahl, and P.J. Peters. 1998. ARF6 targets recycling vesicles to the plasma membrane: insights from an ultrastructural investigation. J. Cell Biol. 140:603-616.
    • (1998) J. Cell Biol. , vol.140 , pp. 603-616
    • D'Souza-Schorey, C.1    Donselaar, E.L.2    Hsu, V.W.3    Yang, C.Y.4    Stahl, P.D.5    Peters, P.J.6
  • 16
    • 0028301408 scopus 로고
    • ARF1(2-17) does not specifically interact with ARF1-dependent pathways. Inhibition by peptide of phospholipases C beta, D and exocytosis in HL60 cells
    • Fensome, A., E. Cunningham, O. Troung, and S. Cockcroft. 1994. ARF1(2-17) does not specifically interact with ARF1-dependent pathways. Inhibition by peptide of phospholipases C beta, D and exocytosis in HL60 cells. FEBS Lett. 349:34-38.
    • (1994) FEBS Lett. , vol.349 , pp. 34-38
    • Fensome, A.1    Cunningham, E.2    Troung, O.3    Cockcroft, S.4
  • 17
    • 0031739953 scopus 로고    scopus 로고
    • Remodeling of the actin cytoskeleton is coordinately regulated by protein kinase C and the ADP-ribosylation factor nucleotide exchange factor ARNO
    • Frank, S.R., J.C. Hatfield, and J.E. Casanova. 1998a. Remodeling of the actin cytoskeleton is coordinately regulated by protein kinase C and the ADP-ribosylation factor nucleotide exchange factor ARNO. Mol. Biol. Cell. 9:3133-3146.
    • (1998) Mol. Biol. Cell , vol.9 , pp. 3133-3146
    • Frank, S.R.1    Hatfield, J.C.2    Casanova, J.E.3
  • 18
    • 0031982629 scopus 로고    scopus 로고
    • ARNO is a guanine nucleotide exchange factor for ADP-ribosylation factor 6
    • Frank, S.R., S. Upendert, S.H. Hansen, and J.E. Casanova. 1998b. ARNO is a guanine nucleotide exchange factor for ADP-ribosylation factor 6. J. Biol. Chem. 278:23-27.
    • (1998) J. Biol. Chem. , vol.278 , pp. 23-27
    • Frank, S.R.1    Upendert, S.2    Hansen, S.H.3    Casanova, J.E.4
  • 20
    • 0031037998 scopus 로고    scopus 로고
    • Regulated exocytosis in chromaffin cells. A potential role for a secretory granule-associated ARF6 protein
    • Galas, M.C., J.B. Helms, N. Vitale, D. Thierse, D. Aunis, and M.F. Bader. 1997. Regulated exocytosis in chromaffin cells. A potential role for a secretory granule-associated ARF6 protein. J. Biol. Chem. 272:2788-2793.
    • (1997) J. Biol. Chem. , vol.272 , pp. 2788-2793
    • Galas, M.C.1    Helms, J.B.2    Vitale, N.3    Thierse, D.4    Aunis, D.5    Bader, M.F.6
  • 21
    • 0034284922 scopus 로고    scopus 로고
    • Regulation of exocytosis in chromaffin cells by phosducin-like protein, a protein interacting with G protein βγ subunits
    • Gensse, M., N. Vitale, S. Chasserot-Golaz, and M.F. Bader. 2000. Regulation of exocytosis in chromaffin cells by phosducin-like protein, a protein interacting with G protein βγ subunits. FEBS Lett. 480:184-188.
    • (2000) FEBS Lett. , vol.480 , pp. 184-188
    • Gensse, M.1    Vitale, N.2    Chasserot-Golaz, S.3    Bader, M.F.4
  • 22
    • 0028340317 scopus 로고
    • Evidence for the involvement of Rab3A in calcium-dependent exocytosis from adrenal chromaffin cells
    • Holz, R.W., W.H. Brondyk, R.A. Senter, L. Kuison, and I.G. Macara. 1994. Evidence for the involvement of Rab3A in calcium-dependent exocytosis from adrenal chromaffin cells. J. Biol. Chem. 269:10229-10234.
    • (1994) J. Biol. Chem. , vol.269 , pp. 10229-10234
    • Holz, R.W.1    Brondyk, W.H.2    Senter, R.A.3    Kuison, L.4    Macara, I.G.5
  • 25
    • 0032836484 scopus 로고    scopus 로고
    • Membrane fusion and exocytosis
    • Jahn, R., and T.C. Südhof. 1999. Membrane fusion and exocytosis. Annu. Rev. Biochem. 68:863-911.
    • (1999) Annu. Rev. Biochem. , vol.68 , pp. 863-911
    • Jahn, R.1    Südhof, T.C.2
  • 26
    • 0033166062 scopus 로고    scopus 로고
    • ADP ribosylation factor 1 mutants identify a phospholipase D effector region an reveal that phospholipase D participates in lysosomal secretion but is not sufficient for recruitment of coatomer I
    • Jones, D.H., B. Bax, A. Fensome, and S. Cockcroft. 1999. ADP ribosylation factor 1 mutants identify a phospholipase D effector region an reveal that phospholipase D participates in lysosomal secretion but is not sufficient for recruitment of coatomer I. Biochem. J. 341:185-192.
    • (1999) Biochem. J. , vol.341 , pp. 185-192
    • Jones, D.H.1    Bax, B.2    Fensome, A.3    Cockcroft, S.4
  • 27
    • 0034130493 scopus 로고    scopus 로고
    • Role of actin cortex in the subplasmalemmal transport of secretory granules in PC12 cells
    • Lang, T., I. Wacker, I. Wuderlinch, A. Rohrbach, G. Giese, T. Soldati, and W. Almers. 2000. Role of actin cortex in the subplasmalemmal transport of secretory granules in PC12 cells. Biophys. 178:2863-2877.
    • (2000) Biophys. , vol.178 , pp. 2863-2877
    • Lang, T.1    Wacker, I.2    Wuderlinch, I.3    Rohrbach, A.4    Giese, G.5    Soldati, T.6    Almers, W.7
  • 28
    • 0034529457 scopus 로고    scopus 로고
    • Phospholipase D in rat myometrium: Occurence of a membrane-bound ARF6 (ADP-ribosylation factor 6)-regulated activity controlled by βγ subunits of heterotrimeric G-proteins
    • Le Stunff, H., L. Dokhac, S. Bourgoin, M.F. Bader, and S. Harbon. 2000. Phospholipase D in rat myometrium: occurence of a membrane-bound ARF6 (ADP-ribosylation factor 6)-regulated activity controlled by βγ subunits of heterotrimeric G-proteins. Biochem. J. 352:491-499.
    • (2000) Biochem. J. , vol.352 , pp. 491-499
    • Le Stunff, H.1    Dokhac, L.2    Bourgoin, S.3    Bader, M.F.4    Harbon, S.5
  • 29
    • 0027986677 scopus 로고
    • Activation of rat brain phospholipase D by ADP-ribosylation factors 1, 5, and 6: Separation of ADP-ribosylation factor-dependent and oleate-dependent enzymes
    • Massenburg, D., J.S. Han, M. Liyanage, W.A. Patton, S.G. Rhe, J. Moss, and M. Vaughan. 1994. Activation of rat brain phospholipase D by ADP-ribosylation factors 1, 5, and 6: separation of ADP-ribosylation factor-dependent and oleate-dependent enzymes. Proc. Natl. Acad. Sci. USA. 91:11718-11722.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 11718-11722
    • Massenburg, D.1    Han, J.S.2    Liyanage, M.3    Patton, W.A.4    Rhe, S.G.5    Moss, J.6    Vaughan, M.7
  • 30
    • 0033580823 scopus 로고    scopus 로고
    • Evidence for a role for ADP-ribosylation factor 6 in insulin-stimulated glucose transporter-4 (GLUT4) trafficking in 3T3-L1 adipocytes
    • Millar, C.A., K.A. Powell, G.X.R. Hickson, M.F. Bader, and G.W. Gould. 1999. Evidence for a role for ADP-ribosylation factor 6 in insulin-stimulated glucose transporter-4 (GLUT4) trafficking in 3T3-L1 adipocytes. J. Biol. Chem. 274:17619-17625.
    • (1999) J. Biol. Chem. , vol.274 , pp. 17619-17625
    • Millar, C.A.1    Powell, K.A.2    Hickson, G.X.R.3    Bader, M.F.4    Gould, G.W.5
  • 31
    • 0028353472 scopus 로고
    • The exocytotic fusion pore and neurotransmitter release
    • Monck, J.R., and J.M. Fernandez. 1994. The exocytotic fusion pore and neurotransmitter release. Neuron. 12:707-716.
    • (1994) Neuron , vol.12 , pp. 707-716
    • Monck, J.R.1    Fernandez, J.M.2
  • 32
    • 0035933883 scopus 로고    scopus 로고
    • Invovement of ADP-ribosylation factor 1 in cholera toxin-induced morphological changes in Chinese hamster ovary cells
    • Morinaga, N., Y. Kaihou, N. Vitale, J. Moss, and M. Noda. 2001. Invovement of ADP-ribosylation factor 1 in cholera toxin-induced morphological changes in Chinese hamster ovary cells. J. Biol. Chem. 276:22838-22843.
    • (2001) J. Biol. Chem. , vol.276 , pp. 22838-22843
    • Morinaga, N.1    Kaihou, Y.2    Vitale, N.3    Moss, J.4    Noda, M.5
  • 33
    • 0032555493 scopus 로고    scopus 로고
    • Molecules in the ARF orbit
    • Moss, J., and M. Vaughan. 1998. Molecules in the ARF orbit. J. Biol. Chem. 273:21431-21434.
    • (1998) J. Biol. Chem. , vol.273 , pp. 21431-21434
    • Moss, J.1    Vaughan, M.2
  • 36
    • 0028951905 scopus 로고
    • Overexpression of wild-type and mutant ARF1 and ARF6: Distinct perturbations of nonoverlapping membrane compartments
    • Peters, P.J., V.W. Hsu, C.E. Ooi, D. Finazzi, S.B. Teal, V. Oorscht, J.G. Donaldson, and R.D. Klausner. 1995. Overexpression of wild-type and mutant ARF1 and ARF6: distinct perturbations of nonoverlapping membrane compartments. J. Cell Biol. 128:1003-1017.
    • (1995) J. Cell Biol. , vol.128 , pp. 1003-1017
    • Peters, P.J.1    Hsu, V.W.2    Ooi, C.E.3    Finazzi, D.4    Teal, S.B.5    Oorscht, V.6    Donaldson, J.G.7    Klausner, R.D.8
  • 37
    • 0032476669 scopus 로고    scopus 로고
    • Regulation of exocytosis from rat peritoneal mast cells by G protein βγ-subunits
    • Pinxteren, J.A., A.J. O'Sullivan, P.E.R. Tatham, and B.G. Gomperts. 1998. Regulation of exocytosis from rat peritoneal mast cells by G protein βγ-subunits. EMBO J. 17:6210-6218.
    • (1998) EMBO J. , vol.17 , pp. 6210-6218
    • Pinxteren, J.A.1    O'Sullivan, A.J.2    Tatham, P.E.R.3    Gomperts, B.G.4
  • 38
    • 0030816319 scopus 로고    scopus 로고
    • ADP-ribosylation factor 6 regulates a novel plasma membrane recycling pathway
    • Radhakrishna, H., and J.G. Donaldson. 1997. ADP-ribosylation factor 6 regulates a novel plasma membrane recycling pathway. J. Cell Biol. 139:49-61.
    • (1997) J. Cell Biol. , vol.139 , pp. 49-61
    • Radhakrishna, H.1    Donaldson, J.G.2
  • 39
    • 0032900498 scopus 로고    scopus 로고
    • ARF6 requirement for Rac ruffling suggests a role for membrane trafficking in cortical actin rearrangements
    • Radhakrishna, H., O. Al-Awar, Z. Khachikian, and J.G. Donaldson. 1999. ARF6 requirement for Rac ruffling suggests a role for membrane trafficking in cortical actin rearrangements. J. Cell Sci. 112:855-866.
    • (1999) J. Cell Sci. , vol.112 , pp. 855-866
    • Radhakrishna, H.1    Al-Awar, O.2    Khachikian, Z.3    Donaldson, J.G.4
  • 40
    • 0035817625 scopus 로고    scopus 로고
    • Activation of ARF6 by ARNO stimulates epithelial cell migration through downstream activation of both Rac1 and phospholipase D
    • Santy, L.C., and J.E. Casanova. 2001. Activation of ARF6 by ARNO stimulates epithelial cell migration through downstream activation of both Rac1 and phospholipase D. J. Cell Biol. 154:599-610.
    • (2001) J. Cell Biol. , vol.154 , pp. 599-610
    • Santy, L.C.1    Casanova, J.E.2
  • 42
    • 0037155210 scopus 로고    scopus 로고
    • Mechanism of ARF-stimulated phosphatidylinositol 4,5-bisphosphate synthesis in HL60 cells
    • Skippen, A., D.H. Jones, C.P. Morgan, M. Li, and S. Cockcroft. 2002. Mechanism of ARF-stimulated phosphatidylinositol 4,5-bisphosphate synthesis in HL60 cells. J. Biol. Chem. 277:5823-5831.
    • (2002) J. Biol. Chem. , vol.277 , pp. 5823-5831
    • Skippen, A.1    Jones, D.H.2    Morgan, C.P.3    Li, M.4    Cockcroft, S.5
  • 43
    • 0031690587 scopus 로고    scopus 로고
    • Localization of endogenous ARF6 to sites of cortical actin rearrangement and involvement of ARF6 in cell spreading
    • Song, J., Z. Khachikian, H. Radhakrishna, and J.G. Donaldson. 1998. Localization of endogenous ARF6 to sites of cortical actin rearrangement and involvement of ARF6 in cell spreading. J. Cell Sci. 111:2257-2267.
    • (1998) J. Cell Sci. , vol.111 , pp. 2257-2267
    • Song, J.1    Khachikian, Z.2    Radhakrishna, H.3    Donaldson, J.G.4
  • 45
    • 0034043451 scopus 로고    scopus 로고
    • Two pathways control chromaffin cell cortical F-actin dynamics during exocytosis
    • Trifaro, J.M., S.D. Rosé, T. Lejen, and A. Elzagallai. 2000. Two pathways control chromaffin cell cortical F-actin dynamics during exocytosis. Biochimie. 82:339-352.
    • (2000) Biochimie , vol.82 , pp. 339-352
    • Trifaro, J.M.1    Rosé, S.D.2    Lejen, T.3    Elzagallai, A.4
  • 46
    • 0031054516 scopus 로고    scopus 로고
    • Interaction of the GTP-binding and the GTPase-activating domains of ARD1 involves the effector region of the ADP-ribosylation factor domain
    • Vitale, N., J. Moss, and M. Vaughan. 1997. Interaction of the GTP-binding and the GTPase-activating domains of ARD1 involves the effector region of the ADP-ribosylation factor domain. J. Biol. Chem. 272:3897-3904.
    • (1997) J. Biol. Chem. , vol.272 , pp. 3897-3904
    • Vitale, N.1    Moss, J.2    Vaughan, M.3
  • 47
    • 0033826667 scopus 로고    scopus 로고
    • Identification of lysosomal and Golgi signals in GAP and ARF domains of ARF-domain protein 1 (ARD1)
    • Vitale, N., V.J. Ferrans, J. Moss, and M. Vaughan. 2000a. Identification of lysosomal and Golgi signals in GAP and ARF domains of ARF-domain protein 1 (ARD1). Mol. Cell Biol. 20:7342-7352.
    • (2000) Mol. Cell Biol. , vol.20 , pp. 7342-7352
    • Vitale, N.1    Ferrans, V.J.2    Moss, J.3    Vaughan, M.4
  • 48
    • 0034607876 scopus 로고    scopus 로고
    • GIT proteins, a novel family of P1P3-Stimulated GTPase-activating proteins for ARF6
    • Vitale, N., W.A. Paton, J. Moss, M. Vaughan, R.J. Lefkowitz, and R.T. Premont. 2000b. GIT proteins, a novel family of P1P3-Stimulated GTPase-activating proteins for ARF6. J. Biol. Chem. 275:13901-13906.
    • (2000) J. Biol. Chem. , vol.275 , pp. 13901-13906
    • Vitale, N.1    Paton, W.A.2    Moss, J.3    Vaughan, M.4    Lefkowitz, R.J.5    Premont, R.T.6
  • 51
    • 0000036684 scopus 로고    scopus 로고
    • ADP-ribosylation factor 6 (ARF6) defines two insulin-regulated secretory pathways in adipocytes
    • Yang, C.Z., and M. Muekler. 1999. ADP-ribosylation factor 6 (ARF6) defines two insulin-regulated secretory pathways in adipocytes. J. Biol. Chem. 274:25297-25300.
    • (1999) J. Biol. Chem. , vol.274 , pp. 25297-25300
    • Yang, C.Z.1    Muekler, M.2
  • 52
    • 0035119307 scopus 로고    scopus 로고
    • A novel procedure for pre-embedding double immuno-gold-silver labeling at the ultrastructural level
    • Yi, H., J.L.M. Leunissen, G.M. Shi, C.A. Gutekunst, and S.M. Hersch. 2001. A novel procedure for pre-embedding double immuno-gold-silver labeling at the ultrastructural level. J. Histochem. Cytochem. 49:279-283.
    • (2001) J. Histochem. Cytochem. , vol.49 , pp. 279-283
    • Yi, H.1    Leunissen, J.L.M.2    Shi, G.M.3    Gutekunst, C.A.4    Hersch, S.M.5
  • 53
    • 0033512845 scopus 로고    scopus 로고
    • ARF6 is required for growth factor- and rac-mediated membrane ruffling in macrophages at a stage distal to rac membrane targeting
    • Zhang, Q., J. Calafat, H. Jansen, and S. Greenberg. 1999a. ARF6 is required for growth factor- and rac-mediated membrane ruffling in macrophages at a stage distal to rac membrane targeting. Mol. Cell. Biol. 12:8158-8168.
    • (1999) Mol. Cell. Biol. , vol.12 , pp. 8158-8168
    • Zhang, Q.1    Calafat, J.2    Jansen, H.3    Greenberg, S.4
  • 54
    • 0033570923 scopus 로고    scopus 로고
    • Loss of receptor regulation by a phospholipase D1 mutant unresponsive to protein kinase C
    • Zhang, Y., Y.A. Altshuller, S.A. Hammond, F. Hayes, A.J. Morris, and M.A. Frohman. 1999b. Loss of receptor regulation by a phospholipase D1 mutant unresponsive to protein kinase C. EMBO J. 18:6339-6348.
    • (1999) EMBO J. , vol.18 , pp. 6339-6348
    • Zhang, Y.1    Altshuller, Y.A.2    Hammond, S.A.3    Hayes, F.4    Morris, A.J.5    Frohman, M.A.6


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