Hypotension caused by extracorporeal circulation: Serotonin from pump-activated platelets triggers nitric oxide release

Circulation

Volumn 106, Issue 20, 2002, Pages 2588-2593

  Borgdorff, Piet ^a   Fekkes, Durk ^a   Tangelder, Geert Jan ^a  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Endothelium; Platelets; Receptors; Stress; Vasodilation

Indexed keywords

NITRIC OXIDE; PIZOTIFEN; RITANSERIN; SEROTONIN; SEROTONIN RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARDIOPULMONARY BYPASS; CAROTID ARTERY; CONTROLLED STUDY; DRUG INHIBITION; DRUG RECEPTOR BINDING; EXTRACORPOREAL CIRCULATION; FEMORAL ARTERY; HEART PERFUSION; HEMODIALYSIS; HEMODYNAMICS; HYPOTENSION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR BLOCKING; SEROTONIN BLOOD LEVEL; SEROTONIN RELEASE; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION; VASODILATATION;

ANIMALS; BLOOD PRESSURE; ENZYME INHIBITORS; EXTRACORPOREAL CIRCULATION; HYPOTENSION; INFUSION PUMPS; KINETICS; MALE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PLATELET AGGREGATION; RATS; RATS, WISTAR; SEROTONIN; SEROTONIN ANTAGONISTS; VASCULAR RESISTANCE;

EID: 0037069340     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.0000036082.04708.83     Document Type: Article

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