The incremental direct costs associated with behavioral symptoms in AD

Neurology

Volumn 59, Issue 11, 2002, Pages 1721-1729

  Murman, Daniel L ^a   Chen, Q ^a   Powell, M C ^a   Kuo, S B ^a   Bradley, C J ^b   Colenda, C C ^b  

^a East Lansing   (United States)

^b MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGED; ALZHEIMER DISEASE; ARTICLE; BEHAVIOR; CAREGIVER; CLINICAL FEATURE; COGNITIVE DEFECT; COMORBIDITY; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; HEALTH CARE COST; HEALTH CARE UTILIZATION; HEALTH SERVICE; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTIPLE REGRESSION; PRIORITY JOURNAL;

EID: 0037058753     PISSN: 00283878     EISSN: None     Source Type: Journal    
DOI: 10.1212/01.WNL.0000036904.73393.E4     Document Type: Article

References (54)

1. Cummings JL. The Neuropsychiatric Inventory. Assessing psychopathology in dementia patients. Neurology 1997;48: S10-S16.
2. Mega MS, Cummings JL, Fiorello T, Gornbein J. The spectrum of behavioral changes in Alzheimer's disease. Neurology 1996;46:130-135.
3. Lyketsos CG, Steinberg M, Tschanz JT, Norton MC, Steffens DC, Breitner JCS. Mental and behavioral disturbances in dementia: Findings from the Cache County study on memory and aging. Am J Psychiatry 2000;157:708-714.
4. Kaufer DI, Cummings JL, Christine D, et al. Assessing the impact of neuropsychiatric symptoms in Alzheimer's disease: The Neuropsychiatric Inventory Caregiver Distress Scale. J Am Geriatr Soc 1998;46:210-215.
5. Schulz R, O'Brien AT, Bookwala J, Fleissner K. Psychiatric and physical morbidity effects of dementia caregiving: Prevalence, correlates, and causes. Gerontologist 1995;35:771-791.
6. Yaffe K, Fox P, Newcomer R, et al. Patient and caregiver characteristics and nursing home placement in patients with dementia. JAMA 2002;287:2090-2097.
7. Steele C, Rovner B, Chase GA, Folstein M. Psychiatric symptoms and nursing home placement of patients with Alzheimer's disease. Am J Psychiatry 1990;147:1049-1051.
8. O'Donnell BF, Drachman DA, Barnes HJ, Peterson KE, Swearer JM, Lew RA. Incontinence and troublesome behaviors predict institutionalization in dementia. J Geriatr Psychiatry Neurol 1992;5:45-52.
9. Stern Y, Tang MX, Albert MS, et al. Predicting time to nursing home care and death in individuals with Alzheimer disease. JAMA 1997;277:806-812.
10. Smith GE, O'Brien PC, Ivnik RJ, Kokmen E, Tangalos EG. Prospective analysis of risk factors for nursing home placement of dementia patients. Neurology 2001;57:1467-1473.
11. Ernst RL, Hay JW, Fenn C, Tinklenberg J, Yesavage JA. Cognitive function and the costs of Alzheimer disease. An exploratory study. Arch Neurol 1997;54:687-693.
12. Hux MJ, O'Brien BJ, Iskedjian M, Goeree R, Gagnon M, Gauthier S. Relation between severity of Alzheimer's disease and costs of caring. CMAJ 1998;159:457-465.
13. Small GW, McDonnell DD, Brooks RL, Papadopoulos G. The impact of symptom severity on the cost of Alzheimer's disease. J Am Geriatr Soc 2002;50:321-327.
14. Moore MJ, Zhu CW, Clipp EC. Informal costs of dementia care: Estimates from the National Longitudinal Caregiving Study. J Gerontol B Psychol Sci Soc Sci 2001;56:S219-S228.
15. Beeri MS, Werner P, Davidson M, Noy S. The cost of behavioral and psychological symptoms of dementia (BPSD) in community dwelling Alzheimer's disease patients. Int J Geriatr Psychiatry 2002;17:403-408.
16. McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM. Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's disease. Neurology 1984;34:939-944.
17. McKeith LG, Galasko D, Kosaka K, et al. Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB): Report of the consortium on DLB international workshop. Neurology 1996;47:1113-1124.
18. Tombaugh TN, McIntyre NJ. The mini-mental state examination: A comprehensive review. J Am Geriatr Soc 1992;40:922-935.
19. Parmelee PA, Thuras PD, Katz IR, Lawton MP. Validation of the Cumulative Illness Rating Scale in a geriatric residential population. J Am Geriatr Soc 1995;43:130-137.
20. Richards M, Marder K, Bell K, Dooneief G, Mayeux R, Stern Y. Interrater reliability of extrapyramidal signs in a group assessed for dementia. Arch Neurol 1991;48:1147-1149.
21. Clipp EC, Moore MJ. Caregiver time use: An outcome measure in clinical trial research on Alzheimer's disease. Clin Pharmacol Ther 1995;58:228-236.
22. Gold M, Siegel J, Russell L, Weinstein M. Cost-Effectiveness in Health and Medicine. New York: Oxford University Press, 1996.
23. US Department of Health and Human Services, Agency for Health Care Research and Quality. Expenses and Sources of Payment for Nursing Home Residents, 1996. AHRQ Pub. No. 01-0010. Washington, DC: US Department of Health and Human Services, 2000.
24. Leon J, Moyer D. Potential cost savings in residential care for Alzheimer's disease patients. Gerontologist 1999;39:440-449.
25. US Department of Health and Human Services, Agency for Health Care Research and Quality. Health Care Expenses in the United States, 1996. AHRQ Pub. No. 01-0009. Washington, DC: US Department of Health and Human Services, 2000.
26. Gonzalez M. Socioeconomic Characteristics of Medical Practice. Chicago: American Medical Association, 1995.
27. US Department of Labor, National Compensation Survey. Occupational Wages in the United States, 1999. Washington, DC: United States Government Printing Office, 2001.
28. Cox NJ, Reifler BV. Dementia care and respite services program. Alzheimer Dis Assoc Disord 1994;8:113-121.
29. Bureau of Labor Statistics, US Department of Labor. Consumer Price Indexes, 2001. Available at: http://www.bls.gov/cpi/. Accessed June 20, 2002.
30. Duan A. Smearing estimate: A nonparametric retransformation method. J Am Stat Assoc 1983;78:605-611.
31. Feldman H, Gauthier S, Hecker J, Vellas B, Subbiah P, Whalen E. A 24-week, randomized, double-blind study of donepezil in moderate to severe Alzheimer's disease. Neurology 2001;57:613-620.
32. Tariot PN, Solomon PR, Morris JC, Kershaw P, Lilienfeld S, Ding C. A 5-month, randomized, placebo-controlled trial of galantamine in AD. The Galantamine USA-10 Study Group. Neurology 2000;54:2269-2276.
33. De Deyn PP, Rabheru K, Rasmussen A, et al. A randomized trial of risperidone, placebo, and haloperidol for behavioral symptoms of dementia. Neurology 1999;53:946-955.
34. Katz IR, Jeste DV, Mintzer JE, Clyde C, Napolitano J, Brecher M. Comparison of risperidone and placebo for psychosis and behavioral disturbances associated with dementia: A randomized, double-blind trial. Risperidone Study Group J Clin Psychiatry 1999;60:107-115.
35. Street JS, Clark WS, Gannon KS, et al. Olanzapine treatment of psychotic and behavioral symptoms in patients with Alzheimer disease in nursing care facilities: A double-blind, randomized, placebo-controlled trial. The HGEU Study Group. Arch Gen Psychiatry 2000;57:968-976.
36. Nyth AL, Gottfries CG, Lyby K, et al. A controlled multicenter clinical study of citalopram and placebo in elderly depressed patients with and without concomitant dementia. Acta Psychiatr Scand 1992;86:138-145.
37. Taragano FE, Lyketsos CG, Mangone CA, Allegri RF, Comesana Diaz E. A double-blind, randomized, fixed-dose trial of fluoxetine vs. amitriptyline in the treatment of major depression complicating Alzheimer's disease. Psychosomatics 1997; 38:246-252.
38. Katona CL, Hunter BN, Bray J. A double-blind comparison of the efficacy and safely of paroxetine and imipramine in the treatment of depression with dementia. Int J Geriatr Psychiatry 1998;13:100-108.
39. Colenda CC. Managing agitated dementia patients: A decision analysis approach. J Pract Psych Behav Health 1997;3:156-164.
40. Bartels SJ, Colenda CC. Mental health services for Alzheimer's disease. Current trends in reimbursement and public policy, and the future under managed care. Am J Geriatr Psychiatry 1998;6:S85-100.
41. Frank RG, Goldman HH, McGuire TG. Will parity in coverage result in better mental health care? N Engl J Med 2001;345: 1701-1704.
42. Mintzer JE, Colenda C, Waid LR, et al. Effectiveness of a continuum of care using brief and partial hospitalization for agitated dementia patients. Psychiatr Serv 1997;48:1435-1439.
43. Henke CJ, Burchmore MJ. The economic impact of tacrine in the treatment of Alzheimer's disease. Clin Ther 1997;19:330-345.
44. Small GW, Donohue JA, Brooks RL. An economic evaluation of donepezil in the treatment of Alzheimer's disease. Clin Ther 1998;20:838-850.
45. Stewart A, Phillips R, Dempsey G. Pharmacotherapy for people with Alzheimer's disease: A Markov-cycle evaluation of five years' therapy using donepezil. Int J Geriatr Psychiatry 1998; 13:445-453.
46. Neumann PJ, Hermann RC, Kuntz KM, et al. Cost-effectiveness of donepezil in the treatment of mild or moderate Alzheimer's disease. Neurology 1999;52:1138-1145.
47. O'Brien BJ, Goeree R, Hux M, et al. Economic evaluation of donepezil for the treatment of Alzheimer's disease in Canada. J Am Geriatr Soc 1999;47:570-578.
48. Lamb HM, Goa KL. Rivastigmine. A pharmacoeconomic review of its use in Alzheimer's disease. Pharmacoeconomics 2001;19:303-318.
49. Getsios D, Caro JJ, Caro G, Ishak K. Assessment of health economics in Alzheimer's disease (AHEAD): Galantamine treatment in Canada. Neurology 2001;57:972-978.
50. McDaid D. Estimating the costs of informal care for people with Alzheimer's disease: Methodological and practical challenges. Int J Geriatr Psychiatry 2001;16:400-405.
51. Arno PS, Levine C, Memmott MM. The economic value of informal caregiving. Health Aff Millwood 1999;18:182-188.
52. Langa KM, Chernew ME, Kabeto MU, et al. National estimates of the quantity and cost of informal caregiving for the elderly with dementia. J Gen Intern Med 2001;16:770-778.
53. Chen JC, Borson S, Scanlan JM. Stage-specific prevalence of behavioral symptoms in Alzheimer's disease in a multi-ethnic community sample. Am J Geriatr Psychiatry 2000;8:123-133.
54. Corder LS, Woodbury MA, Manton KG. Proxy response patterns among the aged: Effects on estimates of health status and medical care utilization from the 1982-1984 long-term care survey. J Clin Epidemiol 1996;46:173-182.