Hydration, slaving and protein function

Biophysical Chemistry

Volumn 98, Issue 1-2, 2002, Pages 35-48

  Frauenfelder, Hans ^a   Fenimore, P W ^a   McMahon, B H ^a  

^a LOS ALAMOS NATIONAL LABORATORY   (United States)

Author keywords

Hydration; Myoglobin; Protein dynamics; Protein function; Solvent influence; Trehalose

Indexed keywords

CARBON MONOXIDE; GLOBULAR PROTEIN; MYOGLOBIN; SOLVENT;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; HYDRATION; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN FUNCTION; SPECIES DIFFERENCE; TEMPERATURE DEPENDENCE; VISCOSITY; WILD TYPE;

ANIMALS; CARBON MONOXIDE; DATA INTERPRETATION, STATISTICAL; DIFFUSION; HORSES; KINETICS; MODELS, CHEMICAL; MYOGLOBIN; PHOTOLYSIS; PROTEIN CONFORMATION; SOLVENTS; TEMPERATURE; THERMODYNAMICS; TREHALOSE; VISCOSITY; WATER; WHALES;

CETACEA; EQUUS CABALLUS; PHYSETER CATODON;

EID: 0037054839     PISSN: 03014622     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0301-4622(02)00083-2     Document Type: Article

References (71)

1. From molecular to modular cell biology
2. Proteomics in genomeland
3. Nuclear structure: Protein dynamics: Implications for nuclear architecture and gene expression
4. Protein reaction-kinetics in a room-temperature glass
5. Geminate rebinding and conformational dynamics of myoglobin embedded in a glass at room temperature
6. Harmonic behavior of trehalose-coated carbonmonoxy myoglobin at high temperature
7. Structure of myoglobin
8. Structural dynamics of myoglobin
9. The role of structure, energy landscape, dynamics, and allostery in the enzymatic function of myoglobin
10. Does picosecond protein dynamics have survival value?
11. Dynamics of ligand-binding to myoglobin
12. Binding of xenon to sperm whale myoglobin
13. Cavities in proteins: Structure of a metmyoglobin-xenon complex solved to 1.9 Å
14. Structure and dynamics of water surrounding biomolecules
15. Protein hydration and function
16. Hydration in protein crystallography
17. Protein hydration in aqueous solution
18. Protein hydration dynamics in aqueous solution
19. Protein hydration in solution: Experimental observation by X-ray and neutron scattering
20. The temperature dependence of internal molecular motions in hydrated and dry alpha-amylase: The role of hydration water in the dynamical transition of proteins
21. Residence times of water molecules in the hydration sites of myoglobin
22. Neutron-diffraction study of carbonmonoxy myoglobin
23. A global-model of the protein-solvent interface
24. Using buried water molecules to explore the energy landscape of proteins
25. Time-resolved hole-burning study on myoglobin: Fluctuation of restricted water within distal pocket
26. Protein conformational relaxational and ligand migration in myoglobin: A nanosecond to millisecond molecular movie from time-resolved Laue X-ray diffraction
27. Viscosity-dependent structural fluctuations in enzyme catalysis
28. Solvent viscosity and protein dynamics
29. The role of solvent viscosity in the dynamics of protein conformational changes
30. Conformational relaxation and ligand-binding in myoglobin
31. 2 escape from respiratory proteins as a function of cosolvent molecular-weight
32. Solvent composition and viscosity effects on the kinetics of CO binding to horse myoglobin
33. Crystal structure of photolyzed carbonmonoxy myoglobin
34. X-Ray structure determination of a metastable state of carbonmonoxy myoglobin after photodissociation
35. Photolysis-induced structural changes in single crystals of carbonmonoxy myoglobin at 40 K
36. Initial trajectory of carbon monoxide after photodissociation from myoglobin at cryogenic temperatures
37. Structure of a ligand-binding intermediate in wild-type carbonmonoxy myoglobin
38. Ligand binding and conformational motions in myoglobin
39. 2 entry into and exit from myoglobin
40. The energy landscapes and motions of proteins
41. Energy landscape and fluctuations in proteins
42. Protein states and protein quakes
43. Infrared spectroscopy of photodissociated carboxymyoglobin at low temperatures
44. Rebinding and relaxation in the myoglobin pocket
45. Crystal structures of CO-, deoxy- and met-myoglobins at various pH values
46. Glassy behavior of a protein
47. Ligand binding to heme proteins. VI. Interconversion of taxonomic substates in carbonmonoxy myoglobin
48. Temperature-derivative spectroscopy: A tool for protein dynamics
49. Ligand binding to heme proteins: The effect of light on ligand binding in myoglobin
50. Ligand migration in sperm whale myoglobin
51. Spectroscopic effects of polarity and hydration in the distal heme pocket of deoxymyoglobin
52. A reduction of protein specific motions in co-ligated myoglobin embedded in a trehalose glass
53. Solvent mobility and the protein 'glass' transition
54. Dynamics of ligand binding to heme proteins
55. Multiple conformational states of proteins: A molecular-dynamics analysis of myoglobin
56. Structural basis of hierarchical multiple substates of a protein. II. Monte Carlo simulation of native thermal fluctuations and energy minimization
57. Brownian motion in a field of force and the diffusion model of chemical reactions
58. Rate theories and puzzles of heme protein kinetics
59. Reaction-rate theory: 50 years after Kramers
60. Viscosity scaling and protein dynamics
61. Solvent damping of internal processes in myoglobin studied by specific-heat spectroscopy and flash photolysis
62. Do vibrational spectroscopies uniquely describe protein dynamics? The case for myoglobin
63. Hole-burning spectroscopy and physics of proteins
64. CO binding to heme proteins: A model for barrier height distributions and slow conformational changes
65. A temperature-dependent effective potential explains CO is binding to myoglobin
66. Trehalose prevents myoglobin collapse and preserves its internal mobility
67. Ligand binding to heme proteins: Connection between dynamics and function
68. Geminate recombination of carbon monoxide to myoglobin