메뉴 건너뛰기




Volumn 87, Issue 6, 2002, Pages 591-599

Raltitrexed treatment promotes systemic inflammatory reaction in patients with colorectal carcinoma

Author keywords

5 fluorouracil; Carmofur; Colorectal cancer; Cytokine; Raltitrexed; Systemic inflammation

Indexed keywords

C REACTIVE PROTEIN; CARMOFUR; FLUOROURACIL; FOLINIC ACID; INTERLEUKIN 6; INTERLEUKIN 8; RALTITREXED; TUMOR NECROSIS FACTOR ALPHA;

EID: 0037048308     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjc.6600520     Document Type: Article
Times cited : (10)

References (34)
  • 2
  • 3
    • 0026874127 scopus 로고
    • Members of the American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference Committee: American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference: Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis
    • Anonymous (1992) Members of the American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference Committee: American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference: Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Crit Care Med 20: 864-874
    • (1992) Crit Care Med , vol.20 , pp. 864-874
  • 4
    • 34548470595 scopus 로고    scopus 로고
    • Drug-company decision to end cancer trial
    • Anonymous (1999) Drug-company decision to end cancer trial. Lancet 354: 1045
    • (1999) Lancet , vol.354 , pp. 1045
  • 5
    • 0031838984 scopus 로고    scopus 로고
    • Oxaliplatin plus 5-fluorouracil: Clinical experience in patients with advanced colorectal cancer
    • Bleiberg H, de Gramont A (1998) Oxaliplatin plus 5-fluorouracil: clinical experience in patients with advanced colorectal cancer. Semin Oncol 25: 32-39
    • (1998) Semin Oncol , vol.25 , pp. 32-39
    • Bleiberg, H.1    De Gramont, A.2
  • 6
    • 0030587937 scopus 로고    scopus 로고
    • Immunologic dissonance: A continuing evolution in our understanding of the systemic inflammatory response syndrome (SIRS) and the multiple organ dysfunction syndrome (MODS)
    • Bone RC (1996) Immunologic dissonance: a continuing evolution in our understanding of the systemic inflammatory response syndrome (SIRS) and the multiple organ dysfunction syndrome (MODS). Ann Intern Med 125: 680-687
    • (1996) Ann Intern Med , vol.125 , pp. 680-687
    • Bone, R.C.1
  • 8
    • 0031671255 scopus 로고    scopus 로고
    • Open, randomized, multicenter trial of raltitrexed versus fluorouracil plus high-dose leucovorin in patients with advanced colorectal cancer
    • Tomudex Colorectal Cancer Study Group
    • Cocconi G, Cunningham D, Van Cutsem E, Francois E, Gustavsson B, van Hazel G, Kerr D, Possinger K, Hietschold SM (1998) Open, randomized, multicenter trial of raltitrexed versus fluorouracil plus high-dose leucovorin in patients with advanced colorectal cancer. Tomudex Colorectal Cancer Study Group. J Clin Oncol 16: 2943-2952
    • (1998) J Clin Oncol , vol.16 , pp. 2943-2952
    • Cocconi, G.1    Cunningham, D.2    Van Cutsem, E.3    Francois, E.4    Gustavsson, B.5    Van Hazel, G.6    Kerr, D.7    Possinger, K.8    Hietschold, S.M.9
  • 9
    • 5544237608 scopus 로고    scopus 로고
    • Final results of a randomised trial comparing 'Tomudex' (raltitrexed) with 5-fluorouracil plus leucovorin in advanced colorectal cancer
    • 'Tomudex' Colorectal Cancer Study Group
    • Cunningham D, Zalcberg JR, Rath U, Oliver I, van Cutsem E, Svensson C, Seitz JF, Harper P, Kerr D, Perez-Manga G (1996) Final results of a randomised trial comparing 'Tomudex' (raltitrexed) with 5-fluorouracil plus leucovorin in advanced colorectal cancer. 'Tomudex' Colorectal Cancer Study Group. Ann Oncol 7: 961-965
    • (1996) Ann Oncol , vol.7 , pp. 961-965
    • Cunningham, D.1    Zalcberg, J.R.2    Rath, U.3    Oliver, I.4    Van Cutsem, E.5    Svensson, C.6    Seitz, J.F.7    Harper, P.8    Kerr, D.9    Perez-Manga, G.10
  • 10
    • 0031019918 scopus 로고    scopus 로고
    • Randomized trial comparing monthly low-dose leucovorin and fluorouracil bolus with bimonthly high-dose leucovorin and fluorouracil bolus plus continuous infusion for advanced colorectal cancer: A French intergroup study
    • de Gramont A, Bosset JF, Milan C, Rougier P, Bouche O, Etienne PL, Morvan F, Louvet C, Guillot T, Francois E, Bedenne L (1997) Randomized trial comparing monthly low-dose leucovorin and fluorouracil bolus with bimonthly high-dose leucovorin and fluorouracil bolus plus continuous infusion for advanced colorectal cancer: a French intergroup study. J Clin Oncol 15: 808-815
    • (1997) J Clin Oncol , vol.15 , pp. 808-815
    • De Gramont, A.1    Bosset, J.F.2    Milan, C.3    Rougier, P.4    Bouche, O.5    Etienne, P.L.6    Morvan, F.7    Louvet, C.8    Guillot, T.9    Francois, E.10    Bedenne, L.11
  • 13
    • 0002639092 scopus 로고    scopus 로고
    • Qualitative and chronological assessment of toxicities during treatment with raltitrexed ('tomudex') in 861 patients: Implications for patient management
    • abstract 222
    • Garcia-Vargas JE, Sahmoud T, Smith MP, Green S (1999) Qualitative and chronological assessment of toxicities during treatment with raltitrexed ('tomudex') in 861 patients: Implications for patient management. Eur J Cancer 35:72 (abstract 222)
    • (1999) Eur J Cancer , vol.35 , pp. 72
    • Garcia-Vargas, J.E.1    Sahmoud, T.2    Smith, M.P.3    Green, S.4
  • 17
    • 0000820889 scopus 로고    scopus 로고
    • Preliminary results of a multicentre randomised trial comparing 3 chemotherapy regimens (de Gramont, Lokich and Raltitrexed) in metastatic colorectal cancer
    • abstract 1007
    • Maughan TS, James RD, Kerr D, McArdle C, Ledermann JA, Seymour M, Johnston C, Stephens R (1999) Preliminary Results of a Multicentre Randomised Trial Comparing 3 Chemotherapy Regimens (de Gramont, Lokich and Raltitrexed) in Metastatic Colorectal Cancer. Proc Am Soc Clin Oncol 18: 262a (abstract 1007)
    • (1999) Proc Am Soc Clin Oncol , vol.18
    • Maughan, T.S.1    James, R.D.2    Kerr, D.3    McArdle, C.4    Ledermann, J.A.5    Seymour, M.6    Johnston, C.7    Stephens, R.8
  • 18
    • 0023923359 scopus 로고
    • Synthesis and secretion of multiple forms of beta 2-interferon/B-cell differentiation factor 2/hepatocyte-stimulating factor by human fibroblasts and monocytes
    • May LT, Ghrayeb J, Santhanam U, Tatter SB, Sthoeger Z, Helfgott DC, Chiorazzi N, Grieninger G, Sehgal PB (1988) Synthesis and secretion of multiple forms of beta 2-interferon/B-cell differentiation factor 2/hepatocyte-stimulating factor by human fibroblasts and monocytes. J Biol Chem 263: 7760-7766
    • (1988) J Biol Chem , vol.263 , pp. 7760-7766
    • May, L.T.1    Ghrayeb, J.2    Santhanam, U.3    Tatter, S.B.4    Sthoeger, Z.5    Helfgott, D.C.6    Chiorazzi, N.7    Grieninger, G.8    Sehgal, P.B.9
  • 20
    • 0034114527 scopus 로고    scopus 로고
    • Bleomycin-mediated pulmonary toxicity: Evidence for a p53-mediated response
    • Mishra A, Doyle NA, Martin WJC (2000) Bleomycin-mediated pulmonary toxicity: evidence for a p53-mediated response. Am J Respir Cell Mol Biol 22: 543-549
    • (2000) Am J Respir Cell Mol Biol , vol.22 , pp. 543-549
    • Mishra, A.1    Doyle, N.A.2    Martin, W.J.C.3
  • 22
    • 0031202388 scopus 로고    scopus 로고
    • Apoptosis in cultured human colon cancer cells induced by combined treatments with 5-fluorouracil, tumor necrosis factor-alpha and interferon-alpha
    • Oka Y, Naomoto Y, Yasuoka Y, Hatano H, Haisa M, Tanaka N, Orita K (1997) Apoptosis in cultured human colon cancer cells induced by combined treatments with 5-fluorouracil, tumor necrosis factor-alpha and interferon-alpha. Jpn J Clin Oncol 27: 231-235
    • (1997) Jpn J Clin Oncol , vol.27 , pp. 231-235
    • Oka, Y.1    Naomoto, Y.2    Yasuoka, Y.3    Hatano, H.4    Haisa, M.5    Tanaka, N.6    Orita, K.7
  • 23
    • 0034860293 scopus 로고    scopus 로고
    • A phase I study of Raltitrexed (Tomudex) combined with Carmofur in Metastatic Colorectal Cancer
    • Osterlund P, Elomaa I, Virkkunen P, Joensuu H (2001) A phase I study of Raltitrexed (Tomudex) combined with Carmofur in Metastatic Colorectal Cancer. Ontology (Basel) 61: 113-119
    • (2001) Ontology (Basel) , vol.61 , pp. 113-119
    • Osterlund, P.1    Elomaa, I.2    Virkkunen, P.3    Joensuu, H.4
  • 25
    • 0000269364 scopus 로고    scopus 로고
    • Raltitrexed (Tomudex®) versus 5-fluorouracil and leucovorin (5-FU + LV) in patients with advanced colorectal cancer (ACC): Results of a randomized, multicenter North American trial
    • abstract 801
    • Pazdur R, Vincent M (1997) Raltitrexed (Tomudex®) versus 5-fluorouracil and leucovorin (5-FU + LV) in patients with advanced colorectal cancer (ACC): results of a randomized, multicenter North American trial. Proc Am Soc Clin Oncol 16: 228a (abstract 801)
    • (1997) Proc Am Soc Clin Oncol , vol.16
    • Pazdur, R.1    Vincent, M.2
  • 27
    • 0028153776 scopus 로고
    • Immune function of patients receiving recombinant human interleukin-6 (IL-6) in a phase I clinical study: Induction of C-reactive protein and IgE and inhibition of natural killer and lymphokine-activated killer cell activity
    • Scheid C, Young R, McDermott R, Fitzsimmons L, Scarffe JH, Stern PL (1994) Immune function of patients receiving recombinant human interleukin-6 (IL-6) in a phase I clinical study: induction of C-reactive protein and IgE and inhibition of natural killer and lymphokine-activated killer cell activity. Cancer Immunol Immunother 38: 119-126
    • (1994) Cancer Immunol Immunother , vol.38 , pp. 119-126
    • Scheid, C.1    Young, R.2    McDermott, R.3    Fitzsimmons, L.4    Scarffe, J.H.5    Stern, P.L.6
  • 29
    • 0033052026 scopus 로고    scopus 로고
    • Systemic inflammatory response syndrome without systemic inflammation in acutely ill patients admitted to hospital in a medical emergency
    • Takala A, Jousela I, Olkkola KT, Jansson SE (1999) Systemic inflammatory response syndrome without systemic inflammation in acutely ill patients admitted to hospital in a medical emergency. Clin Sci (Colch) 96: 287-295
    • (1999) Clin Sci (Colch) , vol.96 , pp. 287-295
    • Takala, A.1    Jousela, I.2    Olkkola, K.T.3    Jansson, S.E.4
  • 30
    • 0034089252 scopus 로고    scopus 로고
    • Systemic inflammation in hemorrhagic fever with renal syndrome correlates with hypotension and thrombocytopenia but not with renal injury
    • Takala A, Lahdevirta J, Jansson SE, Vapalahti O, Orpana A, Karonen SL, Repo H (2000) Systemic inflammation in hemorrhagic fever with renal syndrome correlates with hypotension and thrombocytopenia but not with renal injury. J Infect Dis 181: 1964-1970
    • (2000) J Infect Dis , vol.181 , pp. 1964-1970
    • Takala, A.1    Lahdevirta, J.2    Jansson, S.E.3    Vapalahti, O.4    Orpana, A.5    Karonen, S.L.6    Repo, H.7
  • 31
    • 0030940081 scopus 로고    scopus 로고
    • The anti-human tumor effect and generation of human cytotoxic T cells in SCID mice given human peripheral blood lymphocytes by the in vivo transfer of the Interleukin-6 gene using adenovirus vector
    • Tanaka F, Abe M, Akiyoshi T, Nomura T, Sugimachi K, Kishimoto T, Suzuki T, Okada M (1997) The anti-human tumor effect and generation of human cytotoxic T cells in SCID mice given human peripheral blood lymphocytes by the in vivo transfer of the Interleukin-6 gene using adenovirus vector. Cancer Res 57: 1335-1343
    • (1997) Cancer Res , vol.57 , pp. 1335-1343
    • Tanaka, F.1    Abe, M.2    Akiyoshi, T.3    Nomura, T.4    Sugimachi, K.5    Kishimoto, T.6    Suzuki, T.7    Okada, M.8
  • 32
    • 0031743688 scopus 로고    scopus 로고
    • Clinical effects of exogenous/endogenous TNF therapy on metastatic lesions of 34 colorectal cancer patients
    • Tomita A, Fuchino Y, Otsuka K, Shinohara T, Tanaka SN, Umeno T, Ikeda S (1998) Clinical effects of exogenous/endogenous TNF therapy on metastatic lesions of 34 colorectal cancer patients. Anticancer Res 18: 3937-3939
    • (1998) Anticancer Res , vol.18 , pp. 3937-3939
    • Tomita, A.1    Fuchino, Y.2    Otsuka, K.3    Shinohara, T.4    Tanaka, S.N.5    Umeno, T.6    Ikeda, S.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.