Systemic inflammatory response syndrome without systemic inflammation in acutely ill patients admitted to hospital in a medical emergency

Clinical Science

Volumn 96, Issue 3, 1999, Pages 287-295

  Takala, Annika ^a   Jousela, Irma ^a   Olkkola, Klaus T ^a   Jansson, Sten Erik ^a   Leirisalo Repo, Marjatta ^a,b   Takkunen, Olli ^a   Repo, Heikki ^a,b  

^a HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^b UNIVERSITY OF HELSINKI   (Finland)

Author keywords

Acute illness; C reactive protein; CD11b; Cytokine; Interleukin; Monocyte; Neutrophil; Systemic inflammatory response syndrome; Tumour necrosis factor

Indexed keywords

ANTIBODY; C REACTIVE PROTEIN; CD11B ANTIGEN; CITRIC ACID; CYTOKINE; DEXTRAN; DYE; INTERLEUKIN 1BETA; INTERLEUKIN 6; REAGENT; TUMOR NECROSIS FACTOR ALPHA;

ACUTE DISEASE; ADOLESCENT; ADULT; AGED; ANTIGEN EXPRESSION; ARTICLE; CLINICAL TRIAL; DEVICE; DIFFERENTIAL DIAGNOSIS; DISEASE SEVERITY; EMERGENCY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HOSPITAL ADMISSION; HUMAN; INFLAMMATION; MAJOR CLINICAL STUDY; MALE; MONOCYTE; NEUTROPHIL; PRIORITY JOURNAL; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME; TUBE;

EID: 0033052026     PISSN: 01435221     EISSN: None     Source Type: Journal    
DOI: 10.1042/cs0960287     Document Type: Article

References (43)

1. 1 The ACCP/SCCM Consensus Conference Committee. (1992) Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Chest 101, 1644-1655
2. 2 Rangel-Frausto, M. S., Pittet, D., Costigan, M., Hwang, T., Davis, C. S. and Wenzel, R. P. (1995) The natural history of the systemic inflammatory response syndrome (SIRS). A prospective study. J. Am. Med. Assoc. 273, 117-123
3. 3 Rosenbloom, A. J., Pinsky, M. R., Bryant, J. L., Shin, A., Tran, T. and Whiteside, T. (1995) Leukocyte activation in the peripheral blood of patients with cirrhosis of the liver and SIRS. Correlation with serum interleukin-6 levels and organ dysfunction. J. Am. Med. Assoc. 274, 58-65
4. 4 Salvo, I., de Cian, W., Musicco, M. et al. (1995) The Italian SEPSIS study: preliminary results on the incidence and evolution of SIRS, sepsis, severe sepsis and septic shock. Intensive Care Med. 21, S244-S249
5. 5 Smail, N., Messiah, A., Edouard, A. et al. (1995) Role of systemic inflammatory response syndrome and infection in the occurrence of early multiple organ dysfunction syndrome following severe trauma. Intensive Care Med. 21, 813-816
6. 6 Rixen, D., Siegel, J. H. and Friedman, H. P. (1996) 'Sepsis/SIRS,' physiologic classification, severity stratification, relation to cytokine elaboration and outcome prediction in posttrauma critical illness. J. Trauma 41, 581-598
7. 7 Headley, A. S., Tolley, E. and Meduri, U. (1997) Infections and the inflammatory response in acute respiratory distress syndrome. Chest 111, 1306-1321
8. 8 Bonten, M. J. M., Froon, A. H. M., Gaillard, C. A. et al. (1997) The systemic inflammatory response in the development of ventilator-associated pneumonia. Am. J. Respir. Crit. Care Med. 156, 1105-1113
9. 9 Hayden, W. R. (1993) Sepsis and organ failure definitions and guidelines. Crit. Care Med. 21, 1612-1613
10. 10 Bone, R. C. (1995) Sepsis, sepsis syndrome, and the systemic inflammatory response syndrome (SIRS). Gulliver in Laputa. J. Am. Med. Assoc. 273, 155-156
11. 11 Baue, A. E. (1997) Multiple organ failure, multiple organ dysfunction syndrome, and systemic inflammatory response syndrome. Why no magic bullets? Arch. Surg. 132, 703-707
12. 12 Tracey, K. J. (1991) Tumor necrosis factor (cachectin) in the biology of septic shock syndrome. Circ. Shock 35, 123-128
13. 13 Okusawa, S., Gelfand, J. A., Ikejima, T., Connolly, R. J. and Dinarello, D. A. (1988) Interleukin-1 induces a shock-like state in rabbits. Synergism with tumour necrosis factor and the effect of cyclooxygenase inhibition. J. Clin. Invest. 81, 1162-1172
14. 14 Damas, P., Ledoux, D., Nys, M. et al. (1992) Cytokine serum level during severe sepsis in human. IL-6 as a marker of severity. Ann. Surg. 215, 356-362
15. 15 Morley, J. J. and Kushner, I. (1982) Serum C-reactive protein levels in disease. Ann. N. Y. Acad. Sci. 389, 406-418
16. 16 Vedder, N. B. and Harlan, J. M. (1988) Increased surface expression of CD11b/CD18 (Mac-1) is not required for stimulated neutrophil adherence to cultured endothelium. J. Clin. Invest. 81, 676-682
17. 17 Freyer, D. R., Morganroth, M. L., Rogers, C. E., Arnaout, M. A. and Todd, III, R. F. (1988) Modulation of surface CD11/CD18 glycoproteins (Mol, LFA-1, p150,95) by human mononuclear phagocytes. Clin. Immunol. Immunopathol. 46, 272-283
18. 18 Repo, H., Jansson, S.-E. and Leirisalo-Repo, M. (1993) Flow cytometric determination of CD11b upregulation in vivo. J. Immunol. Methods 164, 193-202
19. 19 Lin, R. Y., Astiz, M. E., Saxon, J. C. and Rackow, E. C. (1993) Altered leukocyte immunophenotypes in septic shock. Studies of HLA-DR, CD11b, CD14, and IL-2R expression. Chest 104, 847-853
20. 2) upregulation on neutrophils and monocytes after coronary artery bypass grafting. Scand. J. Thorac. Cardiovasc. Surg. 30, 141-148
21. 21 Arnaout, M. A., Hakim, R. M., Todd, III, R. F., Dana, N. and Colten, H. R. (1985) Increased expression of an adhesion-promoting surface glycoprotein in the granulocytopenia of hemodialysis. N. Engl. J. Med. 312, 457-462
22. 22 Repo, H., Jansson, S.-E. and Leirisalo-Repo, M. (1995) Anticoagulant selection influences flow cytometric determination of CD11b upregulation in vivo and ex vivo. J. Immunol. Methods 185, 65-79
23. 23 Damas, P., Canivet, J.-L., De Groote, D. et al. (1997) Sepsis and serum cytokine concentrations. Crit. Care Med. 25, 405-412
24. 24 Casey, L. C., Balk, R. B. and Bone, R. C. (1993) Plasma cytokine and endotoxin levels correlate with survival in patients with the sepsis syndrome. Ann. Intern. Med. 119, 771-778
25. 25 Pinsky, M. R., Vincent, J.-L., Deviere, J., Alegre, M., Kahn, R. J. and Dupont, E. (1993) Serum cytokine levels in human septic shock. Relation to multiple-system organ failure and mortality. Chest 103, 565-575
26. 26 Takala, A., Jousela, I., Olkkola, K. T. et al. (1997) Levels of CD11b expression and plasma interleukin-6 predict development of organ failure in sepsis. Shock (Suppl.) 7, 12
27. 27 Yentis, S. M., Soni, N. and Sheldon, J. (1995) C-reactive protein as an indicator of resolution of sepsis in the intensive care unit. Intensive Care Med. 21, 602-605
28. 28 Nakayama, T., Sonoda, S., Urano, T., Yamada, T. and Okada, M. (1993) Monitoring both serum amyloid protein A and C-reactive protein as inflammatory markers in infectious diseases. Clin. Chem. 39, 293-297
29. 29 Mustonen, J., Partanen, J., Kanerva, M. et al. (1996) Genetic susceptibility to severe course of nephropathia epidemica caused by Puumala hantavirus. Kidney Int. 49, 217-221
30. 30 Calafat, J., Kuijpers, T. W., Janssen, H., Borregaard, N., Verhoeven, A. J. and Roos, D. (1993) Evidence for small intracellular vesicles in human blood phagocytes containing cytochrome b558 and the adhesion molecule CD11b/CD18. Blood 81, 3122-3129
31. 31 Repo, H., Rochon, Y. P., Schwartz, B. R., Sharar, S. R., Winn, R. K. and Harlan, J. M. (1997) Binding of human peripheral blood polymorphonuclear leukocytes to E-selectin (CD62E) does not promote their activation. J. Immunol. 159, 943-951
32. 32 Rinder, C. S., Bonan, J. L., Rinder, H. M., Mathew, J., Hinds, R. and Smith, B. R. (1992) Cardiopulmonary bypass induces leukocyte-platelet adhesion. Blood 79, 1201-1205
33. 33 Lin, R. Y., Astiz, M. E., Saxon, J. C., Saha, D. C. and Rackow, E. C. (1994) Relationships between plasma cytokine concentrations and leukocyte functional antigen expression in patients with sepsis. Crit. Care Med. 22, 1595-1602
34. 34 Botha, A. J., Moore, F. A., Moore, E. E., Sauaia, A., Banerjee, A. and Peterson, V. M. (1995) Early neutrophil sequestration after injury: a pathogenic mechanism for multiple organ failure. J. Trauma 39, 411-417
35. 35 Nelson, R. D., Hasslen, S. R., Ahrenholz, D. H., Haus, E. and Solem, L. D. (1986) Influence of minor thermal injury on expression of complement receptor CR3 on human neutrophils. Am. J. Pathol. 125, 563-570
36. 36 Cremer, J., Martin, M., Redl, H. et al. (1996) Systemic inflammatory response syndrome after cardiac operations. Ann. Thorac. Surg. 61, 1714-1720
37. 37 Waage, A., Brandtzaeg, P., Halstensen, A., Kierulf, P. and Espevik, T. (1989) The complex pattern of cytokines in serum with meningococcal septic shock. Association between interleukin 6, interleukin 1, and fatal outcome. J. Exp. Med. 169, 333-338
38. 38 International Committee for Standardization in Haematology (expert panel on blood rheology). (1988) Guidelines on selection of laboratory tests for monitoring the acute phase response. J. Clin. Pathol. 41, 1203-1212
39. 39 Abrahamsson, J., Påhlman, M. and Mellander, L. (1997) Interleukin 6, but not tumour necrosis factor-α, is a good predictor of severe infection in febrile neutropenic and non-neutropenic children with malignancy. Acta Paediatr. 86, 1059-1064
40. 40 Selby, P., Hobbs, S., Viner, C. et al. (1987) Tumour necrosis factor in man: clinical and biological observations. Br. J. Cancer 56, 803-808
41. 41 Damas, P., Reuter, A., Gysen, P., Demonty, J., Lamy, M. and Franchimont, P. (1989) Tumor necrosis factor and interleukin-1 serum levels during severe sepsis in humans. Crit. Care Med. 17, 975-978
42. 42 Thijs, L. G. and Hack, C. E. (1995) Time course of cytokine levels in sepsis. Intensive Care Med. 21, S258-S263
43. 43 Guillen, I., Blanes, M., Gomez-Lechon, M. J. and Castell, J. V. (1995) Cytokine signaling during myocardial infarction: sequential appearance of IL-1beta and IL-6. Am. J. Physiol. 269, R229-R235