Association between the ras p21 oncoprotein in blood samples and breast cancer

Cancer Letters

Volumn 185, Issue 1, 2002, Pages 71-78

  Rundle, Andrew ^a   Tang, Deliang ^a   Brandt Rauf, Paul ^a   Zhou, Jingzhi ^a   Kelly, Amalia ^b   Schnabel, Freya ^b   Perera, Frederica P ^a  

^a Columbia University ^*  (United States)

^b NEW YORK PRESBYTERIAN HOSPITAL   (United States)

Author keywords

Blood samples; Breast cancer; Ras p21

Indexed keywords

ONCOPROTEIN; PROTEIN P21; TUMOR MARKER;

ARTICLE; BLOOD SAMPLING; BREAST CARCINOMA; BREAST DISEASE; CANCER DIAGNOSIS; CANCER RISK; CLINICAL ARTICLE; CLINICAL TRIAL; COMPUTER ANALYSIS; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; EARLY DIAGNOSIS; FOLLOW UP; HUMAN; IMAGING; POSTOPERATIVE PERIOD; PREOPERATIVE EVALUATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BLOOD LEVEL; RISK FACTOR; SINGLE BLIND PROCEDURE; STAINING; BLOOD; BREAST; BREAST TUMOR; CANCER STAGING; CASE CONTROL STUDY; COMPARATIVE STUDY; FEMALE; METABOLISM; MUTATION; PAGET NIPPLE DISEASE; PROGNOSIS; WESTERN BLOTTING;

BLOTTING, WESTERN; BREAST; BREAST DISEASES; BREAST NEOPLASMS; CARCINOMA, INTRADUCTAL, NONINFILTRATING; CASE-CONTROL STUDIES; COMPARATIVE STUDY; FEMALE; HUMAN; MUTATION; NEOPLASM STAGING; ONCOGENE PROTEIN P21(RAS); PROGNOSIS; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, NON-P.H.S.; TUMOR MARKERS, BIOLOGICAL; HUMANS;

EID: 0037044566     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(02)00236-7     Document Type: Article

References (33)

1. Molecular epidemiology and the environmental carcinogenesis of the lung
2. Detection of increased amounts of the extracellular domain of the c-erb-2 oncoprotein in serum during pulmonary carcinogenesis in humans
3. Utility of c-erbB-2 in tissue and in serum in the early diagnosis of recurrence in breast cancer patients: Comparison with carcinoembryonic antigen and CA153
4. Signal transduction pathways involving ras
5. Immunodetection of the p21-ras products in human normal and preneoplastic tissues and solid tumors: A review
6. The role of p21 ras in receptor tyrosine kinase signaling
7. Ras activation in experimental carcinogenesis
8. Immunohistochemical study of the ras oncogene expression in human breast lesions
9. Advances in cancer biomarkers as applied to chemical exposures: The ras oncogene and p21 protein and pulmonary carcinogenesis
10. The role of ras and myc oncogenes in human solid tumors and their relevance in diagnosis and prognosis
11. Oncogene proteins as biomarkers in the molecular epidemiology of occupational carcinogenesis
12. Expression of p21 ras-related protein in the plasma and tissue of patients with adenomas and carcinomas of the colon
13. Mutant c-Ki-ras p21 protein in chemical carcinogenesis in humans exposed to vinyl chloride
14. Evaluation of oncogene-related proteins in serum
15. Competitive ELISA for detection of native ras gene-related products in sera of cancer patients
16. Serum oncoproteins and growth factors in asbestosis and silicosis patients
17. Measuring agreement between two judges on the presence or absence of a trait
18. Intra-class correlations: Uses in assessing rater reliability
19. The relationship between genetic damage from polycyclic aromatic hydrocarbons in breast tissue and breast cancer
20. Contribution of genetic and nutritional factors to DNA damage in heavy smokers
21. Standardization and validation of DNA adduct postlabelling methods: Report of interlaboratory trials and production of recommended protocols
22. Determination of a fragment of the c-erbB-2 translational product p185 in serum of breast cancer patients
23. C-erbB-2 protein in sera of breast cancer patients
24. Elevated erbB-2 oncoprotein levels in preoperative and follow-up serum samples define an aggressive disease course in patients with breast cancer
25. Detection of C-erbB-2 related protein in sera from breast cancer patients. Relationship to ERBB-2 gene amplification and c-erbB-2 protein overexpression in tumor
26. Serum c-erbB-2 in breast cancer patients
27. Levels of p53 antigen in the plasma of patients with adenomas and carcinomas of the colon
28. Detection of the extracellular domain of c-erbB-2 oncoprotein in sera from patients with various carcinomas: Correlation with tumor markers
29. Circulating tumor markers in breast cancer: Accepted utilities and novel prospects
30. The neu-oncogene product in serum and tissue of patients with breast carcinoma
31. Soluble c-erbB-2 fragment in serum correlates with disease stage and predicts for shortened survival in patients with early-stage and advanced breast cancer
32. The prognostic significance of c-erbB-2 serum protein in metastatic breast cancer