Efficient chemoenzymatic synthesis of (S)- and (R)-5-(1-aminoethyl)-2-(cyclohexylmethoxy)benzamide: Key intermediate for Src-SH2 inhibitor

Bioorganic and Medicinal Chemistry Letters

Volumn 12, Issue 13, 2002, Pages 1735-1738

  Kamal, Ahmed ^a   Sandbhor, Mahendra ^a  

^a INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

5 (1 AMINOMETHYL) 2 (CYCLOHEXYLMETHOXY)BENZAMIDE; BENZAMIDE DERIVATIVE; TRIACYLGLYCEROL LIPASE; UNCLASSIFIED DRUG; BENZOIC ACID DERIVATIVE; ENZYME INHIBITOR; IMMOBILIZED ENZYME; PROTEIN TYROSINE KINASE;

ACYLATION; ARTICLE; DRUG PURITY; DRUG SYNTHESIS; ENANTIOMER; ENANTIOSELECTIVITY; ENZYME IMMOBILIZATION; REDUCTION; BURKHOLDERIA CEPACIA; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; METABOLISM; SRC HOMOLOGY DOMAIN; STEREOISOMERISM; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ACYLATION; BENZAMIDES; BENZOATES; BURKHOLDERIA CEPACIA; ENZYME INHIBITORS; ENZYMES, IMMOBILIZED; LIPASE; SRC HOMOLOGY DOMAINS; SRC-FAMILY KINASES; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; SUPPORT, NON-U.S. GOV'T;

BURKHOLDERIA CEPACIA; PSEUDOMONAS;

EID: 0037042769     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(02)00256-1     Document Type: Article

References (20)