Expression of swelling- and/or pH-regulated chloride channels (ClC-2, 3, 4 and 5) in human leukemic and normal immune cells

Life Sciences

Volumn 70, Issue 12, 2002, Pages 1383-1394

  Jiang, Baohong ^a   Hattori, Naoki ^a   Liu, Bing ^a   Kitagawa, Kaori ^a   Inagaki, Chiyoko ^a,b  

^a KANSAI MEDICAL UNIVERSITY   (Japan)

^b NONE   (Japan)

Author keywords

Chloride channels; Immune cells; Northern blot; RT PCR

Indexed keywords

CHLORIDE CHANNEL;

ADULT; ARTICLE; B LYMPHOCYTE; CANCER CELL CULTURE; CELL MATURATION; CELL SWELLING; CELL TYPE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; HUMAN; HUMAN CELL; IMMUNOCOMPETENT CELL; LEUKEMIA CELL; LYMPHOCYTE FUNCTION; NEUTROPHIL; NORMAL HUMAN; NORTHERN BLOTTING; PH; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; T LYMPHOCYTE;

ADULT; B-LYMPHOCYTES; BLOTTING, NORTHERN; CELL SEPARATION; CHLORIDE CHANNELS; HUMANS; JURKAT CELLS; LEUKOCYTES; NEUTROPHILS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, NEOPLASM; T-LYMPHOCYTES;

EID: 0037040014     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0024-3205(01)01517-X     Document Type: Article

References (22)

1. Small- conductance chloride channels in human peripheral T lymphocytes
2. - current in human T84 colonic and B-cell myeloma cell lines
3. 2+- activated ion channels in human neutrophils
4. Chloride-channel block inhibits T lymphocyte activation and signalling
5. Kuffer cells contain a glycine-gated chloride channel
6. Normotonic cell shrinkage because of disordered volume regulation is an early prerequisite to apoptosis
7. Triggering of chloride ion efflux from human neutrophils as a novel function of leukocyte β 2 integrins: Relationship with spreading and activation of the respiratory burst
8. + ion channel blockers
9. The CLC chloride channel family
10. Single-cell RT-PCR demonstrates expression of voltage-dependent chloride channels (ClC-1, ClC-2 and ClC-3) in outer hair cells of rat cochlea
11. Human lymphocytes express hGH-N gene transcripts of 22kDa, 20kDa and minor forms of GH, but not hGH-V gene
12. Cloning of a putative human voltage-gated chloride channel (ClC-2) cDNA widely expressed in human tissues
13. Characterization of a human and murine gene (CLCN3) sharing similarities to voltage-gated chloride channels and to a yeast integral membrane protein
14. A gene from the Xp22.3 region shares homology with voltage-gated chloride channels
15. Cloning and characterization of CLCN5, the human kidney chloride channel gene implicated in Dent disease (an X-linked hereditary nephrolithiasis)
16. Involvement of ion channels in human eosinophil respiratory burst
17. Expression of CLCN voltage-gated chloride channel genes in human blood vessels
18. Expression and canalicular localization of two isoforms of the ClC-3 chloride channel from rat hepatocytes
19. Ion permeation and selectivity in ClC-type chloride channels
20. Disruption of ClC-3, a chloride channel expressed on synaptic vesicles, leads to a loss of the hippocampus
21. Mutational analysis demonstrates that ClC-4 and ClC-5 directly mediate plasma membrane currents