Thrombolytic therapy of pulmonary embolism: A meta-analysis

Journal of the American College of Cardiology

Volumn 40, Issue 9, 2002, Pages 1660-1667

  Thabut, Gabriel ^a   Thabut, Dominique ^b   Myers, Robert P ^b   Bernard Chabert, Brigitte ^b   Marrash Chahla, Rolana ^a   Mal, Hervé ^a   Fournier, Michel ^a  

^a BEAUJON HOSPITAL   (France)

^b PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ALTEPLASE; FIBRINOLYTIC AGENT; HEPARIN; STREPTOKINASE;

ARTICLE; BLEEDING; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFICACY; DRUG SAFETY; EMBASE; HUMAN; LUNG EMBOLISM; MEDLINE; META ANALYSIS; MORTALITY; OUTCOMES RESEARCH; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RECURRENCE RISK; SCISEARCH; STATISTICAL ANALYSIS;

FIBRINOLYTIC AGENTS; HEMORRHAGE; HEPARIN; HUMANS; PLASMINOGEN ACTIVATORS; PULMONARY EMBOLISM; RECURRENCE; RISK; STREPTOKINASE; TREATMENT OUTCOME; URINARY PLASMINOGEN ACTIVATOR;

EID: 0037032274     PISSN: 07351097     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0735-1097(02)02381-1     Document Type: Article

References (43)

1. Arcasoy SM, Kreit JW. Thrombolytic therapy of pulmonary embolism: A comprehensive review of current evidence. Chest 1999;115:1695-707.
2. Goldhaber SZ. Pulmonary embolism. N Engl J Med 1998;339:93-104.
3. Barritt DW, Jordan SC. Anticoagulants drugs in the treatment of pulmonary embolism, Lancet 1960;1:1309-12.
4. Kasper W, Konstantinides S, Geibel A, et al. Management strategies and determinants of outcome in acute major pulmonary embolism: Results of a multicenter registry. J Am Coll Cardiol 1997;30:1165-71.
5. Goldhaber SZ, Visani L, De Rosa M. Acute pulmonary embolism: Clinical outcomes in the International Cooperative Pulmonary Embolism Registry (ICOPER). Lancet 1999;353:1386-9.
6. Ly B, Arnesen H, Eie H, Hol R. A controlled clinical trial of streptokinase and heparin in the treatment of major pulmonary embolism. Acta Med Scand 1978;203:465-70.
7. Marini C, Di Ricco G, Rossi G, Rindi M, Palla R, Giuntini C. Fibrinolytic effects of urokinase and heparin in acute pulmonary embolism: A randomized clinical trial. Respiration 1988;54:162-73.
8. Levine M, Hirsh J, Weitz J, et al. A randomized trial of a single bolus dosage regimen of recombinant tissue plasminogen activator in patients with acute pulmonary embolism. Chest 1990;98:1473-9.
9. Goldhaber SZ, Haire WD, Feldstein ML, et al. Alteplase versus heparin in acute pulmonary embolism: Randomised trial assessing right-ventricular function and pulmonary perfusion. Lancet 1993;341:507-11.
10. Dalla-Volta S, Palla A, Santolicandro A, et al. PAIMS 2: Alteplase combined with heparin versus heparin in the treatment of acute pulmonary embolism. Plasminogen Activator Italian Multicenter Study 2. J Am Coll Cardiol 1992;20:520-6.
11. Tibbutt DA, Davies JA, Anderson JA, et al. Comparison by controlled clinical trial of streptokinase and heparin in treatment of life-threatening pulmonary embolism. Br Med J 1974;1:343-7.
12. The Urokinase Pulmonary Embolism Trial: A national cooperative study. Circulation 1973;47 Suppl II:II1-108.
13. The PIOPED Investigators. Tissue plasminogen activator for the treatment of acute pulmonary embolism: a collaborative study by the PIOPED Investigators. Chest 1990;97:528-33.
14. Kasper W, Konstantinides S, Geibel A, Tiede N, Krause T, Just H. Prognostic significance of right ventricular afterload stress detected by echocardiography in patients with clinically suspected pulmonary embolism. Heart 1997;77:346-9.
15. Cannon CP, Goldhaber SZ. Cardiovascular risk stratification of pulmonary embolism. Am J Cardiol 1996;78:1149-51.
16. Goldhaber SZ. Pulmonary embolism thrombolysis: Broadening the paradigm for its administration. Circulation 1997;96:716-8.
17. Goldhaber SZ. Contemporary pulmonary embolism thrombolysis. Chest 1995;107:45S-51S.
18. Konstantinides S, Geibel A, Kasper W. Submassive and massive pulmonary embolism: a target for thrombolytic therapy? Thromb Haemost 1999;82 Suppl 1:104-8.
19. Konstantinides S, Geibel A, Olschewski M, et al. Association between thrombolytic treatment and the prognosis of hemodynamically stable patients with major pulmonary embolism: Results of a multicenter registry. Circulation 1997;96:882-8.
20. Dalen JE, Alpert JS, Hirsch J. Thrombolytic therapy for pulmonary embolism: Is it effective? Is it safe? When is it indicated? Arch Intern Med 1997;157:2550-6.
21. Moher D, Cook DJ, Eastwood S, Olkin I, Rennie D, Stroup DF. Improving the quality of reports of meta-analyses of randomised controlled trials: The QUality Of Reporting Of Meta-analyses (QUOROM) statement. Lancet 1999;354:1896-900.
22. L'Abbé KA, Detsky AS, O'Rourke K. Meta-analysis in clinical research. Ann Intern Med 1987;107:224-33.
23. Jadad AR, Moore RA, Carroll D, et al. Assessing the quality of reports of randomized clinical trials: is blinding necessary? Control Clin Trials 1996;17:1-12.
24. Demets DL. Methods for combining randomized clinical trials: Strengths and limitations. Stat Med 1987;6:341-50.
25. Petitti D. Meta-analysis, Decision Analysis, and Cost-effectiveness Analysis: Methods for Quantitative Synthesis in Medicine. New York, NY: Oxford University Press, 2000.
26. Sterne JA, Egger M. Funnel plots for detecting bias in meta-analysis: Guidelines on choice of axis. J Clin Epidemiol 2001;54:1046-55.
27. Egger M, Davey Smith G, Schneider M, Minder C. Bias in metaanalysis detected by a simple, graphical test. BMJ 1997;315:629-34.
28. Jerjes-Sanchez C, Ramirez-Rivera A, de Lourdes Garcia M, et al. Streptokinase and heparin versus heparin alone in massive pulmonary embolism: A randomized controlled trial. J Thromb Thrombolysis 1995;2:227-9.
29. Carson JL, Kelley MA, Duff A, et al. The clinical course of pulmonary embolism. N Engl J Med 1992;326:1240-5.
30. Lau J, Antman EM, Jimenez-Silva J, Kupelnick B, Mosteller F, Chalmers TC. Cumulative meta-analysis of therapeutic trials for myocardial infarction. N Engl J Med 1992;327:248-54.
31. Goldhaber SZ. Thrombolysis in pulmonary embolism: A debatable indication. Thromb Haemost 2001;86:444-51.
32. Goldhaber SZ. Pulmonary embolism thrombolysis: A clarion call for international collaboration. J Am Coll Cardiol 1992;19:246-7.
33. Goldhaber SZ. Thrombolysis in pulmonary embolism: A large-scale clinical trial is overdue. Circulation 2001;104:2876-8.
34. Hamel E, Pacouret G, Vincentelli D, et al. Thrombolysis or heparin therapy in massive pulmonary embolism with right ventricular dilation: Results from a 128-patient monocenter registry. Chest 2001;120:120-5.
35. Konstantinides S, Geibel A, Kasper W. Alteplase improves the clinical course of patients with major pulmonary embolism: A multicenter, randomized, placebo-controlled trial (Management Strategies and Prognosis in Pulmonary Embolism Study 3). J Am Coll Cardiol 2002;39 Suppl A:272A.
36. Kanter DS, Mikkola KM, Patel SR, Parker JA, Goldhaber SZ. Thrombolytic therapy for pulmonary embolism: Frequency of intracranial hemorrhage and associated risk factors. Chest 1997;111:1241-5.
37. Mikkola KM, Patel SR, Parker JA, Grodstein F, Goldhaber SZ. Increasing age is a major risk factor for hemorrhagic complications after pulmonary embolism thrombolysis. Am Heart J 1997;134:69-72.
38. Goldhaber SZ, Kessler CM, Heir JA, et al. Recombinant tissue-type plasminogen activator versus a novel dosing regimen of urokinase in acute pulmonary embolism: A randomized controlled multicenter trial. J Am Coll Cardiol 1992;20:24-30.
39. Meneveau N, Schiele F, Metz D, et al. Comparative efficacy of a two-hour regimen of streptokinase versus alteplase in acute massive pulmonary embolism: Immediate clinical and hemodynamic outcome and one-year follow-up. J Am Coll Cardiol 1998;31:1057-63.
40. LeLorier J, Gregoire G, Benhaddad A, Lapierre J, Derderian F. Discrepancies between meta-analyses and subsequent large randomized, controlled trials. N Engl J Med 1997;337:536-42.
41. Pogue J, Yusuf S. Overcoming the limitations of current meta-analysis of randomised controlled trials. Lancet 1998;351:47-52.
42. Flather MD, Farkouh ME, Pogue JM, Yusuf S. Strengths and limitations of meta-analysis: Larger studies may be more reliable. Control Clin Trials 1997;18:568-79 discussion 661-6.
43. Lambert PC, Sutton AJ, Abrams KR, Jones DR. A comparison of summary patient-level covariates in meta-regression with individual patient data meta-analysis. J Clin Epidemiol 2002;55:86-94.