The mechanism of the irreversible inhibition of estrone sulfatase (ES) through the consideration of a range of methane- and amino-sulfonate-based compounds

Bioorganic and Medicinal Chemistry Letters

Volumn 12, Issue 9, 2002, Pages 1279-1282

  Ahmed, Sabbir ^a   James, Karen ^b   Owen, Caroline P ^a   Patel, Chirag K ^a   Sampson, Luther ^c  

^a KINGSTON UNIVERSITY   (United Kingdom)

^b INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^c NOVARTIS PHARMA AG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYL GROUP; BENZENE DERIVATIVE; ESTRONE SULFATASE; IMINE; MESYLIC ACID DERIVATIVE; PHENYL GROUP; SULFATASE; SULFONIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; DRUG ACTIVITY; ENZYME ACTIVE SITE; ENZYME INHIBITION; ENZYME MECHANISM; HYDROLYSIS;

ENZYME INHIBITORS; METHANE; SULFATASES; SULFONIC ACIDS;

EID: 0037029822     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(02)00137-3     Document Type: Article

References (12)