An allele of HRAS1 3′variable number of tandem repeats is a frailty allele: Implication for an evolutionarily-conserved pathway involved in longevity

Gene

Volumn 286, Issue 1, 2002, Pages 121-126

  Bonafè, Massimiliano ^a   Barbi, Cristiana ^a   Olivieri, Fabiola ^b   Yashin, Anatoli ^c   Andreev, Kirill F ^c   Vaupel, James W ^c   De Benedictis, Giovanna ^d   Rose, Giuseppina ^d   Carrieri, Giuseppina ^d   Jazwinski, S Michal ^e   Franceschi, Claudio ^a,b  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b INRCA   (Italy)

^c MAX PLANCK INSTITUTE FOR DEMOGRAPHIC RESEARCH   (Germany)

^d UNIVERSITY OF CALABRIA   (Italy)

^e LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Aging; HRAS1 polymorphisms; Ras genes; Retrograde response; Stress response

Indexed keywords

MITOCHONDRIAL DNA;

ADULT; AGED; AGING; ALLELE; CELL NUCLEUS; CONFERENCE PAPER; CONTROLLED STUDY; FEMALE; GENE FREQUENCY; GENE LOCUS; GENETIC RISK; GENETIC VARIABILITY; GERM LINE; HAPLOIDY; HUMAN; HUMAN CELL; LIFESPAN; LONGEVITY; MALE; MITOCHONDRIAL GENETICS; MITOCHONDRION; MOLECULAR INTERACTION; MORTALITY; NORMAL HUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; STRESS; TANDEM REPEAT; YEAST;

ADULT; AGE FACTORS; AGED; AGED, 80 AND OVER; ALLELES; DNA, MITOCHONDRIAL; EVOLUTION, MOLECULAR; FEMALE; GENE FREQUENCY; GENES, RAS; GENOTYPE; HAPLOTYPES; HUMANS; ITALY; LONGEVITY; MALE; MIDDLE AGED; MINISATELLITE REPEATS;

SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

EID: 0037029127     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1119(01)00812-5     Document Type: Conference Paper

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