Predicting amino acid residues responsible for enzyme specificity solely from protein sequences

Biotechnology and Bioengineering

Volumn 79, Issue 3, 2002, Pages 295-300

  Shaw, Eudean ^a   Dordick, Jonathan S ^a  

^a RENSSELAER POLYTECHNIC INSTITUTE   (United States)

Author keywords

Bioinformatics; Enzymic substrate specificity; Multiple sequence alignment; Predicting functional residues from protein sequence

Indexed keywords

AMINO ACIDS; BIOCATALYSTS; CHEMICAL BONDS; PROTEINS; STRUCTURE (COMPOSITION); SUBSTRATES;

BINDING SPECIFICITY; SUBSTITUTION MATRIX;

BIOTECHNOLOGY;

AMINO ACID; PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; BINDING AFFINITY; BIOCATALYST; ENZYME SPECIFICITY; ENZYME SUBSTRATE COMPLEX; METHODOLOGY; PREDICTION; PROTEIN FAMILY; SEQUENCE ALIGNMENT;

ADENYLATE CYCLASE; ALGORITHMS; AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; CARRIER PROTEINS; CLUSTER ANALYSIS; DATABASES, PROTEIN; DIMETHYLALLYLTRANSTRANSFERASE; FATTY ACID-BINDING PROTEINS; GUANYLATE CYCLASE; MODELS, STATISTICAL; MOLECULAR SEQUENCE DATA; NEOPLASM PROTEINS; NERVE TISSUE PROTEINS; PROTEINS; RATS; RETINOL-BINDING PROTEINS; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS, PROTEIN; SUBSTRATE SPECIFICITY;

EID: 0037026230     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/bit.10289     Document Type: Article

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