Heparin-like polymer improved healing of gastric and colic ulceration

Journal of Biomedical Materials Research

Volumn 60, Issue 3, 2002, Pages 497-501

  Collier, T O ^a   Anderson, J M ^a  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

Colitis; Gastric ulceration; Heparin like molecule; RGTA; Synthetic polymer; Wound healing

Indexed keywords

BIOPOLYMERS; DERIVATIVES; DRUG DOSAGE;

ORAL ADMINISTRATION;

BODY FLUIDS;

ALCOHOL; DEXTRAN DERIVATIVE; HEPARIN DERIVATIVE; POLYMER; RGTA11; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COLON MUCOSA; COLON ULCER; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFECT; INJURY SCALE; MALE; NONHUMAN; RAT; STOMACH ACID SECRETION; STOMACH PROTECTION; STOMACH ULCER; ULCER HEALING; WOUND HEALING;

ANIMALS; COLITIS; HEPARIN; MALE; POLYMERS; RATS; RATS, SPRAGUE-DAWLEY; STOMACH ULCER; WOUND HEALING;

EID: 0037024112     PISSN: 00219304     EISSN: None     Source Type: Journal    
DOI: 10.1002/jbm.1293     Document Type: Article

References (30)

1. Optimizing the pharmacology of acid control in acid-related disorders
2. Proton pump inhibitors. Pharmacology and rationale for use in gastrointestinal disorders
3. Ulcerogenesis: Iintegrating the roles of helicobacter pylori and acid secretion in duodenal ulcer
4. Inflammatory mediators in gastrointestinal defense and injury
5. Unfractioned heparin in the therapy of patients with highly active inflammatory bowel disease
6. Paradoxical response to heparin in 10 patients with ulcerative colitis
7. Different molecular forms of basic fibroblast growth factor (BFGF) accelerate duodenal ulcer healing in rats
8. Accelerated healing of duodenal ulcers by oral administration of a mutein of basic fibroblast growth factor in rats
9. Fibroblast growth factor in gastroprotection and ulcer healing: Interaction with sucralfate
10. Short report: Effect of sucralfate on angiogenesis in granulation tissue of acetic acid-induced gastric ulcers in rats
11. Control of angiogenesis by heparin and other sulfated polysaccharides
12. Derivatized dextrans mimic heparin as stabilizers, potentiators and protectors of acidic or basic FGFs
13. New concepts in tissue repair: Skin as an example
14. FGF protection and inhibition of human neutrophil elastase by carboxymethyl benzylamide sulfonate dextran derivatives
15. Inhibition by dextran derivatives of FGF-2 plasmin-mediated degradation
16. Modulation of cranial bone healing with a heparin-like dextran derivative
17. A single low dose of RGTA, a new healing agent, hastens wound maturation and enhances bone deposition in rat craniotomy defects
18. RGTA11, a new healing agent, triggers developmental events during healing of craniotomy defects in adult rats
19. A substituted dextran enhances muscle fiber survival and regeneration in ischemic and denervated rat EDL muscle
20. New agents for the treatment of infarcted myocardium
21. Heparin-like polymers derived from dextran enhance colonic anastomosis resistance to leakage
22. Anticoagulant activity of dextran derivatives. I. Synthesis and characterization
23. Heparin in inflammation: Potential therapeutic applications beyond anticoagulation
24. Cytoprotection by prostaglandins in rats
25. New approaches to tissue regeneration and repair
26. Human plasmin enzymatic activity is inhibited by chemically modified dextrans
27. Structural studies of the binding of the anti-ulcer drug sucrose octasulfate to acidic fibroblast growth factor
28. Inflammatory bowel disease: Potential therapeutic strategies
29. Medical therapy of inflammatory bowel disease for the 21st century
30. Anti-complementary activity of dextran derivatives